An Association between the Radiation-Induced Arrest of G2-Phase Cells and Low-Dose Hyper-Radiosensitivity: A Plausible Underlying Mechanism?

2003 ◽  
Vol 160 (1) ◽  
pp. 38-45 ◽  
Author(s):  
B. Marples ◽  
B. G. Wouters ◽  
M. C. Joiner
Keyword(s):  
Low Dose ◽  
Underlying Mechanism ◽  
Radiation Induced ◽  
G2 Phase

Enhanced levels of radiation-induced G2 phase delay in ataxia telangiectasia heterozygotes

1992 ◽  
Vol 60 (2) ◽  
pp. 183-187 ◽  
Author(s):  
Martin F. Lavin ◽  
Priscilla Le Poidevin ◽  
Paul Bates
Keyword(s):  
Ataxia Telangiectasia ◽  
Phase Delay ◽  
Radiation Induced ◽  
G2 Phase

scholarly journals A novel role for bone marrow-derived cells to recover damaged keratinocytes from radiation-induced injury

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Junko Okano ◽  
Yuki Nakae ◽  
Takahiko Nakagawa ◽  
Miwako Katagi ◽  
Tomoya Terashima ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Underlying Mechanism ◽  
Basal Cells ◽  
Barrier Dysfunction ◽  
Skin Injury ◽  
Accelerated Proliferation ◽  
Radiation Induced ◽  
Bone Marrow Derived Cells ◽  
Injury Recovery

AbstractExposure to moderate doses of ionizing radiation (IR), which is sufficient for causing skin injury, can occur during radiation therapy as well as in radiation accidents. Radiation-induced skin injury occasionally recovers, although its underlying mechanism remains unclear. Moderate-dose IR is frequently utilized for bone marrow transplantation in mice; therefore, this mouse model can help understand the mechanism. We had previously reported that bone marrow-derived cells (BMDCs) migrate to the epidermis-dermis junction in response to IR, although their role remains unknown. Here, we investigated the role of BMDCs in radiation-induced skin injury in BMT mice and observed that BMDCs contributed to skin recovery after IR-induced barrier dysfunction. One of the important mechanisms involved the action of CCL17 secreted by BMDCs on irradiated basal cells, leading to accelerated proliferation and recovery of apoptosis caused by IR. Our findings suggest that BMDCs are key players in IR-induced skin injury recovery.

Low-dose radiation-induced acute pericarditis (AP) in breast cancer patient

2013 ◽  
Vol 18 ◽  
pp. S179-S180 ◽  
Author(s):  
I. Alastuey ◽  
A. Noé ◽  
C. Chiaramello ◽  
S. Montemuiño ◽  
J. Pardo
Keyword(s):  
Breast Cancer ◽  
Cancer Patient ◽  
Breast Cancer Patient ◽  
Low Dose ◽  
Low Dose Radiation ◽  
Acute Pericarditis ◽  
Radiation Induced ◽  
Dose Radiation

Radiation-induced hypersensitivity from low dose exposures

1998 ◽  
Vol 42 (1) ◽  
pp. 191
Author(s):  
Lewis G. Smith ◽  
Richard C. Miller ◽  
Marcia Richards ◽  
Eric J. Hall
Keyword(s):  
Low Dose ◽  
Radiation Induced

scholarly journals Induction of somatic mutations by low-dose X-rays: the challenge in recognizing radiation-induced events

2017 ◽  
Vol 59 (suppl_2) ◽  
pp. ii11-ii17 ◽  
Author(s):  
Haruki Nagashima ◽  
Kumiko Shiraishi ◽  
Saori Ohkawa ◽  
Yuki Sakamoto ◽  
Kenshi Komatsu ◽  
...  
Keyword(s):  
Low Dose ◽  
Somatic Mutations ◽  
X Rays ◽  
Radiation Induced
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