Analysis of Boron DistributionIn Vivofor Boron Neutron Capture Therapy using Two Different Boron Compounds by Secondary Ion Mass Spectrometry

2007 ◽  
Vol 167 (1) ◽  
pp. 102-109 ◽  
Author(s):  
Kunio Yokoyama ◽  
Shin-Ichi Miyatake ◽  
Yoshinaga Kajimoto ◽  
Shinji Kawabata ◽  
Atsushi Doi ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Boron Neutron Capture Therapy ◽  
Neutron Capture ◽  
Secondary Ion Mass Spectrometry ◽  
Neutron Capture Therapy ◽  
Boron Compounds ◽  
Boron Neutron Capture ◽  
Ion Mass Spectrometry ◽  
Secondary Ion

scholarly journals Microdistribution and quantification of the boron neutron capture therapy drug BPA in primary cell cultures of human glioblastoma tumour by NanoSIMS

The Analyst ◽  
2019 ◽  
Vol 144 (21) ◽  
pp. 6214-6224
Author(s):  
Samar Aldossari ◽  
Greg McMahon ◽  
Nicholas P. Lockyer ◽  
Katie L. Moore
Keyword(s):  
Neutron Capture ◽  
Secondary Ion Mass Spectrometry ◽  
Drug Distribution ◽  
High Sensitivity ◽  
Biological Tissues ◽  
Neutron Capture Therapy ◽  
Boron Neutron Capture ◽  
Medium Mass ◽  
Distribution Studies ◽  
Secondary Ion

The ability of secondary ion mass spectrometry (SIMS) to provide high sensitivity imaging of elements and small-medium mass molecules in biological tissues and cells, makes it a very powerful tool for drug distribution studies.

Intracellular target delivery of cell-penetrating peptide-conjugated dodecaborate for boron neutron capture therapy (BNCT)

2019 ◽  
Vol 55 (93) ◽  
pp. 13955-13958 ◽  
Author(s):  
Ikuhiko Nakase ◽  
Miku Katayama ◽  
Yoshihide Hattori ◽  
Miki Ishimura ◽  
Shunsuke Inaura ◽  
...  
Keyword(s):  
Boron Neutron Capture Therapy ◽  
Neutron Capture ◽  
Cell Penetrating Peptides ◽  
Cell Penetrating Peptide ◽  
Neutron Capture Therapy ◽  
Boron Compounds ◽  
Target Delivery ◽  
Boron Neutron Capture ◽  
Cell Penetrating ◽  
Intracellular Target

Boron neutron capture therapy (BNCT) technology using cell-penetrating peptides (CPPs) for enhanced cellular uptake of boron compounds and their controlled localization inside cells.

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