ABSENCE OF ACUTE TOXICITY OF A SINGLE INTRAMUSCULAR INJECTION OF MELOXICAM IN GOLDFISH (CARASSIUS AURATUS AURATUS): A RANDOMIZED CONTROLLED TRIAL

2018 ◽  
Vol 49 (3) ◽  
pp. 617-622
Author(s):  
Cédric B. Larouche ◽  
Marie-Josée Limoges ◽  
Stéphane Lair
Keyword(s):  
Randomized Controlled Trial ◽  
Acute Toxicity ◽  
Carassius Auratus ◽  
Intramuscular Injection ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
Goldfish Carassius Auratus ◽  
Single Intramuscular Injection

scholarly journals Does an integrated boost increase acute toxicity in prone hypofractionated breast irradiation? A randomized controlled trial

2017 ◽  
Vol 122 (1) ◽  
pp. 30-36 ◽  
Author(s):  
Leen Paelinck ◽  
Akos Gulyban ◽  
Ferenc Lakosi ◽  
Tom Vercauteren ◽  
Werner De Gersem ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Acute Toxicity ◽  
Controlled Trial ◽  
Breast Irradiation ◽  
Randomized Controlled ◽  
Integrated Boost

scholarly journals Let’s Prefer the Pain Reducing Intervention, Buzzy or ShotBlocker: A Randomized Controlled Trial

2020 ◽  
Author(s):  
Burcu Aykanat Girgin ◽  
Eda Aktaş ◽  
Derya Kılınç ◽  
Duygu Gözen
Keyword(s):  
Randomized Controlled Trial ◽  
Intramuscular Injection ◽  
Rating Scale ◽  
Controlled Trial ◽  
Pediatric Emergency ◽  
Parental Satisfaction ◽  
University Hospital ◽  
Control Group ◽  
Randomized Controlled ◽  
Lower Pain

INTRODUCTION: The aim of this study was to detect and compare the effects of ShotBlocker and Buzzy methods on pain, fear, and parental satisfaction during intramuscular injection. METHODS: This study was an experimental randomized controlled trial. The sample included 90 children at the ages of 6 and 12 to whom intramuscular injection was administered in the pediatric emergency department of a university hospital. The participants were randomly assigned to ShotBlocker (n=30), Buzzy (n=30), and control (n=30) groups. Child Information Form, Wong-Baker FACES Pain Rating Scale, Children’s Fear Scale, and Parental Satisfaction Questionnaire were used to collect the data. RESULTS: ShotBlocker and Buzzy groups had significantly lower pain and fear scores and higher parental satisfaction than control group after the procedure (p=0.0001). The lowest pain and fear score and the highest parental satisfaction score were observed in Buzzy group (p=0.0001). DISCUSSION AND CONCLUSION: Both ShotBlocker and Buzzy methods reduce pain and fear of children during intramuscular injection and increasing satisfaction of their parents. However, when compared to ShotBlocker, Buzzy method is more effective in reducing intramuscular injection-related pain and fear and should be preferred primarily.

scholarly journals Effectiveness of PainAway® on hepatitis B intramuscular injection in term neonates: a randomized controlled trial

2010 ◽  
Vol 50 (4) ◽  
pp. 214 ◽  
Author(s):  
Susilawati Susilawati ◽  
Soetjiningsih Soetjiningsih ◽  
Bagus Ngurah Putu Arhana ◽  
Ida Bagus Subanada
Keyword(s):  
Randomized Controlled Trial ◽  
Hepatitis B ◽  
Intramuscular Injection ◽  
Controlled Trial ◽  
Pain Response ◽  
Term Neonates ◽  
Randomized Controlled ◽  
Distress Level ◽  
Short And Long Term

Background Routine immunization injections are the mostcommon painful procedure in childhood and most of theseinjections are administered in early life. Immunizations can causenegative short- and long-term consequences for children. Childrenwho experience high levels of pain during an immunizationare more likely to have elevated distress level of subsequentinjections.Objective To evaluate the effectiveness of pain away in reducingpain associated with hepatitis B intramuscular injection in termneonates.Methods An open randomized controlled trial on healthy termneonates was conducted between November 2009 and December2009 at Sanglah Hospital in Denpasar, Bali. Subject were selectedrandomized using six-blocked randomization. The sampleswere divided into two groupsto either recieve intramuscularhepatitis B injection using PainAway® and or standard hepatitisB intramuscular injection. The pain response was assessed usingDouleur Aiquedu Noureanu-né(DAN) scale. Mann-Whitney testwas used to analyze the data. The confounding factor that mayhave influenced the pain response was analyzed using multivariateanalysis (ANCOVA).Results Out of 66 subject, DAN scale was significantly lower inintervention group (median 5.0) compared to control (median 7.0)with P < 0.0001. Multivariate analysis showed that the differencein the intervention given was the only variable that influencedthe pain response (P < 0.0001).Conclusion PainAway® can reduce the pain secondary tohepatitis B intramuscular injection on term neonates.

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