Antibiotic Intravenous Regional Perfusion for Successful Resolution of Distal Limb Infections: Two Cases

2008 ◽  
Vol 39 (3) ◽  
pp. 438-444 ◽  
Author(s):  
Christine V. Fiorello ◽  
Janet Beagley ◽  
Scott B. Citino
2016 ◽  
Vol 45 (1) ◽  
pp. 125-132 ◽  
Author(s):  
Margaux L. Edwards-Milewski ◽  
Samantha L. Morello ◽  
Qianqian Zhao ◽  
Cynthia Mattan-Bell

To investigate the normal anatomical distribution of the arterial blood supply, venous drainage and innervation on both the dorsal and plantar aspects of pes region including the level of tarsal joint due to its clinical importance with a little data available. Methods: Ten hind paws of five adult apparently healthy domestic dogs of both sexes; six paws injected, through blood vessels with colored latex neoprene for anatomical dissection and the other four paws injected a contrast mixture of red lead oxide and turpentine oil for the radiographic investigation of blood vessels. In addition to five live dogs used to apply the distal limb local anesthesia with the aid of Needle-Guided Ultrasonography. Results: This investigation revealed that the dorsal and plantar aspects of dog pes region supplied by superficial and deep sets of arteries, veins and nerves. The three dorsal metatarsal arteries originated from the arcuate artery. The medial tarsal vein forming characteristic venous arcades. The 3rd plantar metatarsal artery divided into two axial arteries while the 2nd and 4th continued axially without division. The plantar common digital and metatarsal nerves II, III, IV communicated to give origins of the axial and abaxial plantar proper digital nerves except the abaxials of the 2nd and 5th digits which supplied by a branch from medial plantar nerve and lateral plantar nerve respectively. Conclusion: There were little differences between dogs and other carnivores in vascularization of hind paw with the recommendation of using Needle-Guided Ultrasonography in the distal limb local anesthesia to avoid vascular puncture or damage.


Author(s):  
Dante Cicchetti ◽  
Fred A. Rogosch

In this chapter, a developmental psychopathology conceptualization of child maltreatment is presented as an overarching heuristic with relevance for understanding the development of alcohol and substance use and abuse. This chapter also provides illustrations from research on how child maltreatment contributes to problem substance use in adolescence. Child maltreatment represents an extreme failure of the caregiving environment to provide many of the expectable experiences necessary to facilitate normal developmental processes. Maltreatment ushers in a probabilistic epigenesis for children characterized by an increased likelihood of failure and disruption in the successful resolution of major developmental tasks. These repeated disruptions lead to compromised developmental organizations of diverse developmental systems that increase the probability of the emergence of maladaptation, psychopathology, and substance abuse as negative transactions between the child and the environment ensue. Person-centered personality organizations and genetic moderation of maltreatment risk on substance use outcomes are also highlighted.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Florian Bitsch ◽  
Philipp Berger ◽  
Andreas Fink ◽  
Arne Nagels ◽  
Benjamin Straube ◽  
...  

AbstractThe ability to generate humor gives rise to positive emotions and thus facilitate the successful resolution of adversity. Although there is consensus that inhibitory processes might be related to broaden the way of thinking, the neural underpinnings of these mechanisms are largely unknown. Here, we use functional Magnetic Resonance Imaging, a humorous alternative uses task and a stroop task, to investigate the brain mechanisms underlying the emergence of humorous ideas in 24 subjects. Neuroimaging results indicate that greater cognitive control abilities are associated with increased activation in the amygdala, the hippocampus and the superior and medial frontal gyrus during the generation of humorous ideas. Examining the neural mechanisms more closely shows that the hypoactivation of frontal brain regions is associated with an hyperactivation in the amygdala and vice versa. This antagonistic connectivity is concurrently linked with an increased number of humorous ideas and enhanced amygdala responses during the task. Our data therefore suggests that a neural antagonism previously related to the emergence and regulation of negative affective responses, is linked with the generation of emotionally positive ideas and may represent an important neural pathway supporting mental health.


2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Alfredo Páez-Carpio ◽  
Elena Serrano ◽  
Federico Zarco ◽  
Constantino Fondevila ◽  
Marta Burrel

Abstract Background The formation of a hepatic artery pseudoaneurysm in a liver implant is a rare but potentially fatal complication. Fistulization of such pseudoaneurysms into the bile duct is sporadic. The most common causes of hepatic artery pseudoaneurysm are infection at the anastomosis site, inadequate surgical technique, and an iatrogenic origin due to minimally invasive procedures. Currently, there is no standardized treatment in neither of these complications, with surgery and various endovascular procedures among the alternatives available. None of these therapeutic approaches has demonstrated a significant increase in long-term liver implant preservation. Case presentation A 56-year-old man with a two-month liver transplant presented with massive upper gastrointestinal bleeding and hemobilia shortly after the performance of an endoscopic retrograde cholangiopancreatography due to the presence of a hepatic artery pseudoaneurysm with fistulization into the bile duct. This case report describes the successful treatment of both complications, the hepatic artery pseudoaneurysm and the arterio-biliary fistula, using a covered coronary stent placed in the hepatic artery. A year and a half after treatment, the patient maintains a preserved liver implant and a patent hepatic artery. Conclusions Treatment of a hepatic artery pseudoaneurysm with fistulization into bile duct using a covered coronary stent allowed the correct repair of the defect, adequate hemorrhage control, and long-term liver implant preservation.


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