Arginine Exchange and Nitric Oxide Synthesis in Youths under Adaptation to Physical Exercise in Training and Competitive Periods

2011 ◽  
Vol 2 (4) ◽  
pp. 309-319
Author(s):  
Nadezhda V. Bogdanovskaya ◽  
Anatolii V. Kotsiuruba ◽  
Nik V. Malikov
Keyword(s):  
Nitric Oxide ◽  
Physical Exercise ◽  
Nitric Oxide Synthesis ◽  
Adaptation To Physical Exercise

Interleukin-1β-induced nitric oxide synthesis in aortic rings from normal and hyperinsulinaemic rats: effect of physical exercise

1999 ◽  
Vol 360 (1) ◽  
pp. 63-68
Author(s):  
M. Kähönen ◽  
X. Wu ◽  
V.B. Schini-Kerth ◽  
O. Ylikotila ◽  
P. Arvola ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Physical Exercise ◽  
Interleukin 1Β ◽  
Nitric Oxide Synthesis

Age-Dependence in Alterations in Nitric Oxide Synthesis in Cardiovascular System during Adaptation to Physical Training

2010 ◽  
Vol 1 (4) ◽  
pp. 345-356 ◽  
Author(s):  
O. V. Bazilyuk ◽  
Anatolii V. Kotsuruba ◽  
Lyubov. G. Stepanenko ◽  
Sergey A. Talanov ◽  
Yu. P. Korchak ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Cardiovascular System ◽  
Physical Training ◽  
Nitric Oxide Synthesis ◽  
Age Dependence

Chronic Inhibition of Endothelium-Derived Nitric Oxide Synthesis Causes Coronary Microvascular Structural Changes and Hyperreactivity to Serotonin in Pigs

Circulation ◽  
1995 ◽  
Vol 92 (9) ◽  
pp. 2636-2644 ◽  
Author(s):  
Akira Ito ◽  
Kensuke Egashira ◽  
Toshiaki Kadokami ◽  
Yoshihiro Fukumoto ◽  
Tsuneo Takayanagi ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Structural Changes ◽  
Nitric Oxide Synthesis

Effects of Long-term Nitric Oxide Synthesis Inhibition on Plasma Volume Expansion and Fetal Growth in the Pregnant Rat

Hypertension ◽  
1995 ◽  
Vol 26 (6) ◽  
pp. 1019-1023 ◽  
Author(s):  
Sofía P. Salas ◽  
Fernando Altermatt ◽  
Mauricio Campos ◽  
Andrea Giacaman ◽  
Pedro Rosso
Keyword(s):  
Nitric Oxide ◽  
Fetal Growth ◽  
Plasma Volume ◽  
Volume Expansion ◽  
Nitric Oxide Synthesis ◽  
Plasma Volume Expansion ◽  
Pregnant Rat ◽  
Synthesis Inhibition

Arginine Vasopressin Increases Nitric Oxide Synthesis in Cytokine-Stimulated Rat Cardiac Myocytes

Hypertension ◽  
1997 ◽  
Vol 30 (5) ◽  
pp. 1112-1120 ◽  
Author(s):  
Keiji Yamamoto ◽  
Uichi Ikeda ◽  
Koji Okada ◽  
Toshikazu Saito ◽  
Yasuhiro Kawahara ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Cardiac Myocytes ◽  
Arginine Vasopressin ◽  
Nitric Oxide Synthesis ◽  
Rat Cardiac Myocytes

Parathyroid Hormone–Related Protein Upregulates Interleukin-1β–Induced Nitric Oxide Synthesis

Hypertension ◽  
1997 ◽  
Vol 30 (4) ◽  
pp. 922-927 ◽  
Author(s):  
Bingbing Jiang ◽  
Shigeto Morimoto ◽  
Jin Yang ◽  
Keisuke Fukuo ◽  
Atsushi Hirotani ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Parathyroid Hormone ◽  
Interleukin 1Β ◽  
Nitric Oxide Synthesis ◽  
Related Protein ◽  
Parathyroid Hormone Related Protein

scholarly journals Physical Exercise and Cardiac Repair: The Potential Role of Nitric Oxide in Boosting Stem Cell Regenerative Biology

Antioxidants ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 1002
Author(s):  
Fabiola Marino ◽  
Mariangela Scalise ◽  
Eleonora Cianflone ◽  
Luca Salerno ◽  
Donato Cappetta ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Stem Cell ◽  
Physical Exercise ◽  
Cell Biology ◽  
Molecular Mechanisms ◽  
Heart Function ◽  
Stem Cell Biology ◽  
Myocardial Repair ◽  
Beneficial Effects

Over the years strong evidence has been accumulated showing that aerobic physical exercise exerts beneficial effects on the prevention and reduction of cardiovascular risk. Exercise in healthy subjects fosters physiological remodeling of the adult heart. Concurrently, physical training can significantly slow-down or even reverse the maladaptive pathologic cardiac remodeling in cardiac diseases, improving heart function. The underlying cellular and molecular mechanisms of the beneficial effects of physical exercise on the heart are still a subject of intensive study. Aerobic activity increases cardiovascular nitric oxide (NO) released mainly through nitric oxidase synthase 3 activity, promoting endothelium-dependent vasodilation, reducing vascular resistance, and lowering blood pressure. On the reverse, an imbalance between increasing free radical production and decreased NO generation characterizes pathologic remodeling, which has been termed the “nitroso-redox imbalance”. Besides these classical evidence on the role of NO in cardiac physiology and pathology, accumulating data show that NO regulate different aspects of stem cell biology, including survival, proliferation, migration, differentiation, and secretion of pro-regenerative factors. Concurrently, it has been shown that physical exercise generates physiological remodeling while antagonizes pathologic remodeling also by fostering cardiac regeneration, including new cardiomyocyte formation. This review is therefore focused on the possible link between physical exercise, NO, and stem cell biology in the cardiac regenerative/reparative response to physiological or pathological load. Cellular and molecular mechanisms that generate an exercise-induced cardioprotective phenotype are discussed in regards with myocardial repair and regeneration. Aerobic training can benefit cells implicated in cardiovascular homeostasis and response to damage by NO-mediated pathways that protect stem cells in the hostile environment, enhance their activation and differentiation and, in turn, translate to more efficient myocardial tissue regeneration. Moreover, stem cell preconditioning by and/or local potentiation of NO signaling can be envisioned as promising approaches to improve the post-transplantation stem cell survival and the efficacy of cardiac stem cell therapy.

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