Exemplar Abstract for Streptomyces bikiniensis Johnstone and Waksman 1947 (Approved Lists 1980) emend. Nouioui et al. 2018.

2003 ◽  
Author(s):  
Charles Thomas Parker ◽  
Dorothea Taylor ◽  
George M Garrity
Keyword(s):  
Streptomyces Bikiniensis

scholarly journals LACCASE PRODUCING STREPTOMYCES BIKINIENSIS CSC12 ISOLATED FROM COMPOST

2016 ◽  
Vol 6 (2) ◽  
pp. 794-798 ◽  
Author(s):  
P. Devi ◽  
Sujatha Kandasamy ◽  
Sivakumar Uthandi
Keyword(s):  
Streptomyces Bikiniensis

CHARACTERIZATION OF CELL BOUND GLUCOSE ISOMERASE OF Streptomyces bikiniensis

1976 ◽  
Vol 41 (6) ◽  
pp. 1383-1386 ◽  
Author(s):  
Y. K. PARK ◽  
C. CHISAKI ◽  
R. H. MORETTI
Keyword(s):  
Glucose Isomerase ◽  
Streptomyces Bikiniensis

scholarly journals The cloned Streptomyces bikiniensis A-factor determinant.

1985 ◽  
Vol 38 (5) ◽  
pp. 636-641 ◽  
Author(s):  
SUEHARU HORINOUCHI ◽  
MAKOTO NISHIYAMA ◽  
HIDEKI SUZUKI ◽  
YOICHI KUMADA ◽  
TERUHIKO BEPPU
Keyword(s):  
Streptomyces Bikiniensis

A Subtilisin Inhibitor Produced by Streptomyces bikiniensis Possesses a Glutamine Residue at Reactive Site P11

1995 ◽  
Vol 117 (3) ◽  
pp. 609-613 ◽  
Author(s):  
Mahito Terabe ◽  
Shuichi Kojima ◽  
Seiichi Taguchi ◽  
Haruo Momose ◽  
Kin-ichiro Miura
Keyword(s):  
Reactive Site ◽  
Glutamine Residue ◽  
Subtilisin Inhibitor ◽  
Streptomyces Bikiniensis

Screening of melanin biosynthesis inhibitors from marine microalgae using Streptomyces bikiniensis bioassay

1995 ◽  
Vol 9 (9) ◽  
pp. 633-636 ◽  
Author(s):  
Yoji Wachi ◽  
Koji Sode ◽  
Kenichi Horikoshi ◽  
Haruko Takeyama ◽  
Tadashi Matsunaga
Keyword(s):  
Marine Microalgae ◽  
Melanin Biosynthesis ◽  
Biosynthesis Inhibitors ◽  
Streptomyces Bikiniensis

scholarly journals Chalcomycin Biosynthesis Gene Cluster from Streptomyces bikiniensis: Novel Features of an Unusual Ketolide Produced through Expression of the chm Polyketide Synthase in Streptomyces fradiae

2004 ◽  
Vol 48 (12) ◽  
pp. 4703-4712 ◽  
Author(s):  
Shannon L. Ward ◽  
Zhihao Hu ◽  
Andreas Schirmer ◽  
Ralph Reid ◽  
W. Peter Revill ◽  
...  
Keyword(s):  
Double Bond ◽  
Polyketide Synthase ◽  
Amino Sugar ◽  
Open Reading Frames ◽  
Neutral Sugar ◽  
Streptomyces Fradiae ◽  
Biosynthesis Gene Cluster ◽  
Genes Encoding ◽  
Enol Tautomer ◽  
Streptomyces Bikiniensis

ABSTRACT Chalcomycin, a 16-membered macrolide antibiotic made by the bacterium Streptomyces bikiniensis, contains a 2,3-trans double bond and the neutral sugar d-chalcose in place of the amino sugar mycaminose found in most other 16-membered macrolides. Degenerate polyketide synthase (PKS)-specific primers were used to amplify DNA fragments from S. bikiniensis with very high identity to a unique ketosynthase domain of the tylosin PKS. The resulting amplimers were used to identify two overlapping cosmids encompassing the chm PKS. Sequencing revealed a contiguous segment of >60 kb carrying 25 putative genes for biosynthesis of the polyketide backbone, the two deoxysugars, and enzymes involved in modification of precursors of chalcomycin or resistance to it. The chm PKS lacks the ketoreductase and dehydratase domains in the seventh module expected to produce the 2,3-double bond in chalcomycin. Expression of PKS in the heterologous host Streptomyces fradiae, from which the tyl genes encoding the PKS had been removed, resulted in production of at least one novel compound, characterized as a 3-keto 16-membered macrolactone in equilibrium with its 3-trans enol tautomer and containing the sugar mycaminose at the C-5 position, in agreement with the structure predicted on the basis of the domain organization of the chm PKS. The production of a 3-keto macrolide from the chm PKS indicates that a discrete set of enzymes is responsible for the introduction of the 2,3-trans double bond in chalcomycin. From comparisons of the open reading frames to sequences in databases, a pathway for the synthesis of nucleoside diphosphate-d-chalcose was proposed.

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