scholarly journals Genetic Analysis of ABO and Rh Blood Groups in Backward Caste Population of Uttar Pradesh, India

2011 ◽  
Vol 3 (3) ◽  
pp. 07-14 ◽  
Author(s):  
Vandana RAI ◽  
Pradeep KUMAR
Keyword(s):  
Blood Group ◽  
Uttar Pradesh ◽  
Blood Groups ◽  
Blood Type ◽  
Allele Frequency Distribution ◽  
Blood Group System ◽  
Blood Group Antigens ◽  
Group System ◽  
Rhesus Blood Group ◽  
Rhesus Blood Group System

A series of glycoproteins and glycolipids on red blood cell surface constitute blood group antigens. These are AB, A, B and O in ABO blood group system and Rh in rhesus blood group system. A total of 1065 unrelated Backward Caste (OBC) individuals from Uttar Pradesh were studied for the phenotype and allele frequency distribution of ABO and Rh (D) blood groups. Total 1065 samples analyzed, phenotype B blood type has the highest frequency 36.81% (n=392), followed by O (32.68%; n=348), A (23.66%; n=252) and AB (6.85%; n=73). The overall phenotypic frequencies of ABO blood groups were B>O>A>AB. The allelic frequencies of O, A, and B alleles were 0.5819, 0.1674 and 0.2506 respectively. Out of total 1065 samples, 1018 (95.59%) samples were Rh-positive and 47 (4.41%) were Rh-negative. Phenotypic frequency of Rh-negative in Koari, Yadav, Kurmi and Maurya samples were 0.99%, 4%, 1.4% and 7.6% respectively.

scholarly journals Identification and partial characterization of the human erythrocyte membrane component(s) that express the antigens of the LW blood-group system

1986 ◽  
Vol 234 (3) ◽  
pp. 649-652 ◽  
Author(s):  
G Mallinson ◽  
P G Martin ◽  
D J Anstee ◽  
M J A Tanner ◽  
A H Merry ◽  
...  
Keyword(s):  
Blood Group ◽  
Polyacrylamide Gel Electrophoresis ◽  
Broad Band ◽  
Osmotic Fragility ◽  
Human Erythrocytes ◽  
Blood Group System ◽  
Group System ◽  
Normal Human ◽  
Rhesus Blood Group ◽  
Rhesus Blood Group System

Rhnull human erythrocytes lack the antigens of the Rhesus blood-group system, have an abnormal shape, have an increased osmotic fragility, and are associated with mild chronic haemolytic anaemia. Rhnull erythrocytes also lack all antigens of the LW blood-group system, but the functional significance of this deficiency is unknown. We have identified, by immunoblotting with two mouse monoclonal antibodies (BS46 and BS56), the LW-active component(s) in normal human erythrocytes as a broad band of Mr 37 000-47 000 on SDS/polyacrylamide-gel electrophoresis. Treatment of intact human erythrocytes with endoglycosidase F preparation destroyed the epitopes recognized by antibodies BS46 and BS56, suggesting that one or more N-glycosidically linked oligosaccharides are required for the formation of the LW antigens. Estimation of the number of LW antigen sites per erythrocyte by using radioiodinated purified antibody BS46 gave average values of 4400 molecules/cell for Rh(D)-positive adult erythrocytes and 2835 molecules/cell for Rh(D)-negative adult erythrocytes. Like the Rh(D) polypeptide, the LW polypeptide(s) is (are) associated with the cytoskeleton of normal erythrocytes. These results suggest the possibility that the absence of the LW polypeptide may also contribute to the functional and/or morphological abnormalities of Rhnull erythrocytes.

BLOOD GROUP PROBABILITIES BY NEXT OF KIN

2018 ◽  
Vol 34 (3) ◽  
pp. 343-363
Author(s):  
Joost H. J. van Sambeeck ◽  
Nico M. van Dijk ◽  
Wim L. A. M. de Kort ◽  
Henk Schonewille ◽  
Mart P. Janssen
Keyword(s):  
Blood Group ◽  
Mathematical Formulation ◽  
Blood Groups ◽  
Point Of View ◽  
Blood Group System ◽  
Genotype Distribution ◽  
Next Of Kin ◽  
Quadratic Stochastic Operators ◽  
Rhesus Blood Group ◽  
Rhesus Blood Group System

For rare blood groups the recruitment of donor relatives, for example siblings, is expected to be effective, since the probability of a similar rare blood group is likely. However, the likelihood differs between blood groups and is not commonly available. This paper provides a unified mathematical formulation to calculate such likelihoods. From a mathematical and probabilistic point of view, it is shown that these likelihoods can be obtained from the computation of a stationary genotype distribution. This, in turn, can be brought down to a system of quadratic stochastic operators. A generic mathematical approach is presented which directly leads to a stationary genotype distribution for arbitrary blood groups. The approach enables an exact computation for the effectiveness of recruiting next of kin for blood donorship. Next to an illustration of computations for ‘standard’ ABO and Rhesus-D blood groups, it is particularly illustrated for the extended Rhesus blood group system. Also other applications requiring next of kin blood group associations can be solved directly by using the unified mathematical formulation.

scholarly journals ABO blood group system and occurrence of ischemic stroke

2021 ◽  
Author(s):  
Rafaella Chiodini LOTZ ◽  
Carolina da Silveira WELTER ◽  
Silvia Aparecida RAMOS ◽  
Leslie Ecker FERREIRA ◽  
Norberto Luiz CABRAL ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Blood Group ◽  
Cerebrovascular Diseases ◽  
Blood Groups ◽  
Blood Type ◽  
Control Group ◽  
Abo Blood Group ◽  
Blood Group System ◽  
Abo Blood Groups ◽  
Group System

ABSTRACT Background: Ischemic stroke (IS) is a multifactorial disease that presents high rates of morbimortality in Brazil. Several studies proved that there is a link between the ABO blood group system and the occurrence of thrombotic events. Nonetheless, its association with IS is not well established. Objective: For that reason, the purpose hereof was to investigate the relation between the ABO blood groups and the occurrence of IS in a Brazilian cohort of cerebrovascular diseases. Methods: Five hundred and twenty-nine subjects were included over 12 months, from which 275 presented an IS episode and 254 composed the control group. Blood samples were drawn for direct and reverse serotyping. The control and IS groups were compared regarding the traditional risk factors and the distribution of the ABO blood groups. Results: The IS group presented a higher prevalence of systemic arterial hypertension (SAH), diabetes mellitus, smoking habits, family history, cardiopathy, and sedentary lifestyle in comparison with the control group. The AB blood type prevailed among the patients (5.1 vs. 1.6%; p<0.05) and this group had more SAH cases in comparison with the O type group (92.9 vs. 67.3%; p<0.05). Conclusions: Our results suggest that the occurrence of IS is more frequent among patients of the AB blood type.

Seed Agglutinin with Specificity within the Rhesus Blood Group System

Nature ◽  
1968 ◽  
Vol 219 (5154) ◽  
pp. 653-653 ◽  
Author(s):  
G. W. G. BIRD ◽  
JUNE WINGHAM
Keyword(s):  
Blood Group ◽  
Blood Group System ◽  
Group System ◽  
Rhesus Blood Group ◽  
Rhesus Blood Group System

Molecular genetic basis of the human Rhesus blood group system

1993 ◽  
Vol 5 (1) ◽  
pp. 62-65 ◽  
Author(s):  
Isabelle Mouro ◽  
Yves Colin ◽  
Baya Chérif-Zahar ◽  
Jean-Pierre Cartron ◽  
Caroline Le Van Kim
Keyword(s):  
Blood Group ◽  
Genetic Basis ◽  
Molecular Genetic ◽  
Blood Group System ◽  
Group System ◽  
Molecular Genetic Basis ◽  
Rhesus Blood Group ◽  
Rhesus Blood Group System
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