scholarly journals Idiopathic: Prenatal closure of the ductus arteriosus causing fetal hydrops

2020 ◽  
Vol 5 (2) ◽  
Author(s):  
Sandeep M ◽  
Patil US ◽  
Pawer RS ◽  
Gavade VK
2016 ◽  
Vol 27 (4) ◽  
pp. 634-638 ◽  
Author(s):  
Hidekazu Ishida ◽  
Yukiko Kawazu ◽  
Futoshi Kayatani ◽  
Noboru Inamura

AbstractBackgroundA number of case reports show various outcomes of premature closure of the ductus arteriosus in utero, including persistent pulmonary hypertension of the newborn and fetal or neonatal death; however, no study clarifies the clinical observations that are related to their prognoses. We aimed to clarify the prognostic factors of intrauterine ductal closure by a systematic literature review.Data sourcesWe searched PubMed database (1975–2014) to identify case reports and studies on intrauterine closure of the ductus arteriosus, including maternal, fetal, and neonatal clinical information and their prognoses.ResultsWe analysed the data of 116 patients from 39 articles. Of these, 12 (10.3%) died after birth or in utero. Fetal or neonatal death was significantly correlated with fetal hydrops (odds ratio=39.6, 95% confidence interval=4.6–47.8) and complete closure of the ductus arteriosus (odds ratio=5.5, 95% confidence interval=1.2–15.1). Persistent pulmonary hypertension was observed in 33 cases (28.4%), and was also correlated with fetal hydrops (odds ratio=4.2, 95% confidence interval=1.3–4.6) and complete closure of the ductus arteriosus (odds ratio=5.5, 95% confidence interval=1.6–6.0). Interestingly, maternal drug administration was not correlated with the risk of death and persistent pulmonary hypertension.ConclusionsFetal hydrops and complete ductal closure are significant risk factors for both death and persistent pulmonary hypertension. Cardiac or neurological prognoses could be favourable if the patients overcome right heart failure during the perinatal period.


2006 ◽  
Vol 56 (9) ◽  
pp. 554-557 ◽  
Author(s):  
Takeshi Kondo ◽  
Riko Kitazawa ◽  
Naoko Noda-Maeda ◽  
Sohei Kitazawa

2012 ◽  
Vol 15 (1) ◽  
pp. 79-85 ◽  
Author(s):  
Rachel M. Sheridan ◽  
Erik C. Michelfelder ◽  
Kyuran A. Choe ◽  
Allison Divanovic ◽  
Cong Liu ◽  
...  

Ductus arteriosus aneurysm (DAA) is a rare cardiovascular lesion usually diagnosed within the first 2 months of life, or less frequently in the 3rd trimester, by antenatal sonography. The true in utero incidence of DAA is unknown, as most affected fetuses are asymptomatic at birth. Potential complications include thromboembolism, rupture, and death. We report a unique lethal case of a large DAA detected by mid–2nd trimester fetal echocardiography, complicated by stricture and massive occlusive thrombosis extending into the pulmonary artery branches. Stricture and thrombosis of the DAA led to interruption of fetal circulation, cardiac failure, and fetal hydrops, ultimately resulting in fetal demise.


Author(s):  
Vijay K. Gavade ◽  
Ravindra S. Pawar ◽  
Uday S. Patil ◽  
Sandeep M ◽  
Prabhu Teja M

Spontaneous premature closure of the human fetal ductus arteriosus is an uncommon event that often results in significant morbidity and mortality. We present a case of a neonate with prenatal previously not detected intrauterine closure of the ductus arteriosus in a 21-year-old ,G3P1A2L1 mother with type 2 consanguinity at 39 weeks of gestation, with previous scans showing placenta previa grade 1 at  21weeks and Doppler study showing  pericardial effusion at 36weeks.Caesarean section was performed in view of absent progression of labour. A male newborn weighing 4100gm, required bag and mask and intubation. With an excellent neonatal outcome. Finally we suggest that fetal echo in third trimester & maternal education programs to avoid  self-medication and provide training for good diet is necessary.


2008 ◽  
Vol 68 (S 01) ◽  
Author(s):  
DJ Kersten ◽  
J McDougall ◽  
C Schuller ◽  
JP Pfammatter ◽  
L Raio ◽  
...  

2010 ◽  
Vol 222 (S 01) ◽  
Author(s):  
K Echtler ◽  
K Stark ◽  
M Lorenz ◽  
M Schwaiger ◽  
O Genzel-Boroviczény ◽  
...  
Keyword(s):  

Author(s):  
DR Hartge ◽  
A Schroeer ◽  
J Weichert
Keyword(s):  

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