scholarly journals Secondary syphilis: Hepatitis, rashes and prozone phenomenon

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Abdurrahman Kaya ◽  
Sibel Yıldız Kaya ◽  
Ahmet Furkan Kurt ◽  
Meryem Şahin ◽  
Ali Can
Keyword(s):  
Secondary Syphilis ◽  
Prozone Phenomenon

scholarly journals Periostitis in secondary syphilis with prozone phenomenon

Rheumatology ◽  
2016 ◽  
Vol 55 (11) ◽  
pp. 1931-1931
Author(s):  
Thibault Mahévas ◽  
Johan Chanal ◽  
Nathalie Franck ◽  
Sara Laurent ◽  
Marie Françoise Avril ◽  
...  
Keyword(s):  
Secondary Syphilis ◽  
Prozone Phenomenon

Case report and evaluation of the frequency of the prozone phenomenon in syphilis serology - an infrequent but important laboratory phenomenon

Sexual Health ◽  
2012 ◽  
Vol 9 (5) ◽  
pp. 488 ◽  
Author(s):  
Jeffrey J. Post ◽  
Candice Khor ◽  
Virginia Furner ◽  
Don E. Smith ◽  
L. Ross Whybin ◽  
...  
Keyword(s):  
Previous History ◽  
Treponema Pallidum ◽  
Delayed Diagnosis ◽  
Secondary Syphilis ◽  
Serum Samples ◽  
Syphilis Infection ◽  
Reactive Sample ◽  
Assay Result ◽  
History Of ◽  
Prozone Phenomenon

Background Treponema pallidum specific serology generally remains reactive for life. Therefore, the diagnosis of syphilis reinfection relies on clinical assessment and nontreponemal (reagin) serologic testing. The prozone phenomenon can lead to a falsely nonreactive rapid plasma reagin (RPR) assay result. Methods: We report a case of secondary syphilis in a HIV infected patient with a previous history of syphilis infection, where a falsely nonreactive RPR assay was associated with a delayed diagnosis of reinfection and infectious syphilis. The prozone phenomenon was detected in several of the patient’s serum samples collected around this time. We subsequently undertook a prospective evaluation for the prozone phenomenon in 3222 consecutive sera, which were assayed using the RPR assay for clinical purposes over a 10-month period. Results: The overall rate of the prozone phenomenon was 2 out of 3222 samples (0.06%; 95% confidence interval (CI): 0.02–0.22%) and the rate per reactive sample was 2 out of 397 (0.5%; 95% CI: 0.14–1.81%). Conclusion: Clinicians should request RPR testing at dilutions of sera when syphilis is suspected clinically and the RPR assay is nonreactive.

Extensive Nodular Secondary Syphilis With Prozone Phenomenon

2008 ◽  
Vol 144 (8) ◽  
Author(s):  
Maxime Battistella ◽  
Laurence Le Cleach ◽  
Aymeric Lacert ◽  
Pascal Perrin
Keyword(s):  
Secondary Syphilis ◽  
Prozone Phenomenon

scholarly journals Prozone phenomenon in secondary syphilis

2011 ◽  
Vol 32 (1) ◽  
pp. 47 ◽  
Author(s):  
Ruchi Sidana ◽  
HC Mangala ◽  
SB Murugesh ◽  
K Ravindra
Keyword(s):  
Secondary Syphilis ◽  
Prozone Phenomenon

Hypertrophic glossitis in secondary syphilis

1980 ◽  
Vol 116 (10) ◽  
pp. 1103a-1104 ◽  
Author(s):  
D. Kahn
Keyword(s):  
Secondary Syphilis
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