Secondary syphilis with unusual clinical and laboratory findings

1969 ◽  
Vol 99 (2) ◽  
pp. 240-243
Author(s):  
L. Biro
Keyword(s):  
Secondary Syphilis ◽  
Laboratory Findings

scholarly journals A Stubborn Case of Syphilitic Hepatitis

2017 ◽  
Vol 1 (1) ◽  
Author(s):  
Marco Campitelli ◽  
Hassan Al Moussawi ◽  
Nabil Zeineddine ◽  
Stephen Maslak
Keyword(s):  
Intramuscular Injection ◽  
Secondary Syphilis ◽  
Penicillin G ◽  
Hiv Viral Load ◽  
Laboratory Findings ◽  
Case Presentation ◽  
Penicillin Therapy ◽  
Hiv Antibodies ◽  
Macular Rash ◽  
Significant Clinical Improvement

Background Syphilitic hepatitis is a rare occurrence, but delay in its diagnosis can expose patient to unnecessary testing. The treatment available for this condition can also vary from one intramuscular injection of Penicillin G to a 2-weeks course of intravenous penicillin. Case presentation: A 53 years old male, presented for fever and abdominal pain, was found on physical examination to have a macular rash on the palms and soles, with fever and abdominal tenderness. Laboratory findings revealed AST 199 IU/L, ALT 132 IU/L, positive RPR, FTA-ABS and HIV antibodies test and a high HIV viral load. He was diagnosed with secondary syphilis and HIV co-infection. His hepatitis did not improve after intramuscular injection of penicillin G, his symptoms continued to worsen. A liver biopsy was done and revealed acute hepatitis and canalicular cholestasis, without evidence of treponemes. Patient was started on intravenous penicillin. He showed significant clinical improvement, and his LFT normalized. Conclusion: This case describes severe syphilitic hepatitis with unusual cytolytic disturbance of the liver function that failed to improve with one intramuscular penicillin injection. It demonstrates the need of intravenous penicillin therapy to achieve adequate clinical response, particularly in patients with severe laboratory evidence of liver inflammation.

Hypertrophic glossitis in secondary syphilis

1980 ◽  
Vol 116 (10) ◽  
pp. 1103a-1104 ◽  
Author(s):  
D. Kahn
Keyword(s):  
Secondary Syphilis

541 Prognostic signifcance of bedside clinical, electrocardiographic and laboratory findings in patients with congestive heart failure

2003 ◽  
Vol 2 (1) ◽  
pp. 114
Author(s):  
M SHTAINSHNAIDER ◽  
D ALMOZNINOSARAFIAN ◽  
I ALON ◽  
O GORELIC ◽  
S CHACHASHVILY ◽  
...  
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Laboratory Findings
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