scholarly journals Role of frozen section in evaluating follicular neoplasms of thyroid

2019 ◽  
Vol 6 (2) ◽  
pp. 1-4
Author(s):  
P. Veda ◽  
R. Usha Rani ◽  
S. Lakkanna
Keyword(s):  
Frozen Section

scholarly journals Preoperative and intraoperative assesment of myometrial invasion and histological grade in endometrial cancer: Role of MRI and frozen section

2016 ◽  
Author(s):  
Rohit Raghunath Ranade
Keyword(s):  
Endometrial Cancer ◽  
Tumor Size ◽  
Early Stage ◽  
Frozen Section ◽  
Myometrial Invasion ◽  
Tumor Grade ◽  
Endometrial Biopsy ◽  
Intraoperative Frozen Section ◽  
Cervical Involvement

Introduction: The role of systematic lymphadenectomy in clinically early stage endometrial cancer is controversial. A number of factors can predict lymph node metastasis including myometrial invasion, tumor grade in endometrial cancers. The purpose of the present study is to evaluate the accuracy of preoperative MRI and intraoperative frozen section in determining the depth of myometrial invasion, cervical involvement, tumor size and lymph nodal status. We also studied the accuracy of preoperative endometrial biopsy and intraoperative frozen section in determining the grade of the tumor. Materials and Methods: Medical records of 235 consecutive cases of clinically early stage endometrial cancer were reviewed retrospectively. A record of depth of myometrial invasion, tumor size, cervical involvement and presence of enlarged lymph nodes was made on a preoperative MRI. Similarly depth of myometrial invasion, tumor size, cervical involvement and grade of the tumor were recorded on an intraoperative frozen section. The grade of the tumor was also recorded on a preoperative endometrial biopsy. Standard statistical calculations were used. Results: The sensitivity and specificity of MRI for myometrial invasion for the first 160 cases were 81.3 and 75%, respectively while that for frozen section were 80 and 96.2%, respectively. For tumor grade the sensitivity and specificity of preoperative endometrial biopsy were 60 and 95.6%, respectively while that of frozen section were 53.8 and 97.6%, respectively. For cervical involvement the sensitivity of MRI and frozen section was 62.5 and 98.4%, respectively. Updated results of the entire cohort of 235 cases will be presented at the conference if selected. Conclusion: Although the sensitivity of both frozen section and MRI for predicting deep myometrial invasion was similar (80 vs 81.3%) but the specificity (96.2 vs 75%) and negative predictive value (92.7 vs 88.2%) of frozen section were superior to MRI. Both preoperative biopsy and intraoperative frozen section had low sensitivity (60 vs 53.8%) for detecting a high grade lesion.

690 ROLE OF FROZEN SECTION ANALYSIS DURING RADICAL PROSTATECTOMY A 2,641-CASE EXPERIENCE

2012 ◽  
Vol 187 (4S) ◽  
Author(s):  
Yasuhiro Kakiuchi ◽  
Bonnie Choy ◽  
Jennifer Gordetsky ◽  
Guan Wu ◽  
Hani Rashid ◽  
...  
Keyword(s):  
Radical Prostatectomy ◽  
Frozen Section ◽  
Frozen Section Analysis ◽  
Section Analysis

Coccidioides, Cryptococcus, or Blastomyces? A Diagnostic Dilemma Encountered during Frozen Section Evaluation

2012 ◽  
Vol 15 (1) ◽  
pp. 71-75 ◽  
Author(s):  
Colt M. McClain ◽  
Gerald T. Van Horn ◽  
James D. Chappell ◽  
Charles W. Stratton
Keyword(s):  
Frozen Section ◽  
Surgical Pathology ◽  
Fungal Culture ◽  
Diagnostic Dilemma ◽  
Simple Task ◽  
Proximal Ulna ◽  
Irrigation And Debridement ◽  
Fungal Osteomyelitis ◽  
The Right

Intraoperative consultation via frozen section is an important part of modern day surgical pathology. Recognizing fungi in tissues on frozen and permanent sections is not always a simple task, and correctly identifying the agent can be a significant challenge, even for experienced microscopists. We present a case of a 17-year-old boy with chronic osteomyelitis involving the right proximal ulna. During an irrigation and debridement operation, a frozen section was sent to surgical pathology for evaluation. A limited patient history coupled with sparse organisms present in the frozen section led to the diagnosis of fungal osteomyelitis, favor Coccidioides. Follow-up permanent sections with special staining and successful fungal culture clarified the causal agent to be Blastomyces dermatitidis. The role of frozen sections is not to perfectly speciate the fungal pathogen but to describe the morphology and infectious process and provide a differential diagnosis of the candidate fungi. The importance of intraoperative culture in infectious cases cannot be understated, and it is the responsibility of pathologists to inform surgeons that tissue is needed for culture. A brief overview of Blastomyces, including histopathologic features and key microscopic differences from Coccidioides and Cryptococcus, is discussed.

scholarly journals Role of frozen section in the intraoperative management of ovarian masses

2015 ◽  
Vol 20 (2) ◽  
pp. 97-101 ◽  
Author(s):  
Abdel-Baset F. Mohammed ◽  
Vijay K. Ahuja ◽  
Hanan Farghaly
Keyword(s):  
Frozen Section ◽  
Intraoperative Management ◽  
Ovarian Masses

The role of frozen section examination (FSE) during inguinal exploration in 1052 patients with inconclusive testicular lesions

2018 ◽  
Vol 17 (14) ◽  
pp. e3005
Author(s):  
C. Fankhauser ◽  
L. Roth ◽  
N. Grossmann ◽  
B. Kranzbühler ◽  
D. Eberli ◽  
...  
Keyword(s):  
Frozen Section ◽  
Frozen Section Examination ◽  
Testicular Lesions

Assessment of the Role of Intraoperative Frozen Section in Guiding Surgical Staging for Endometrial Cancer

2016 ◽  
Vol 26 (5) ◽  
pp. 918-923 ◽  
Author(s):  
Xiaoyuan Wang ◽  
Li Li ◽  
Janiel M. Cragun ◽  
Setsuko K. Chambers ◽  
Kenneth D. Hatch ◽  
...  
Keyword(s):  
Risk Factors ◽  
Endometrial Cancer ◽  
Tumor Size ◽  
Frozen Section ◽  
Medical Center ◽  
Myometrial Invasion ◽  
Surgical Staging ◽  
Endometrioid Adenocarcinoma ◽  
Intraoperative Frozen Section

ObjectiveThe aim of this study was to assess the role of intraoperative frozen section (FS) in guiding decision making for surgical staging of endometrioid endometrial cancer (EC).MethodsMedical records were collected retrospectively on 112 patients with endometrioid EC, who underwent total hysterectomy and bilateral salpingo-oophorectomy at the University of Arizona Medical Center from January 1, 2010, to December 31, 2014. Only patients with endometrioid adenocarcinoma, grade 1, less than 50% myometrial invasion, and tumor size less than 2 cm determined by intraoperative FS omitted lymphadenectomy; otherwise, surgical staging was performed with lymph node dissection. The FS results were compared with the permanent paraffin sections (PSs) to assess the diagnostic accuracy.ResultsThe concordance rate of different variables between FS and PS in EC was 100%, 89.3% (100/112), 97.3% (109/112), and 95.5% (107/112), respectively, with respecting to histological subtype, grade, myometrial invasion, and tumor size. Diagnostic accurate rate of combined risk factors deciding surgical staging at the time of FS was 95.5% (107/112), and the discordance rate of all risk factors considered between FS and PS was 4.5%, resulting 3 cases (2.7%) undertreated and 2 cases (1.8%) overtreated.ConclusionsDespite nonideal FS evaluation, intraoperative FS diagnosis for EC is highly reliable by providing guidance for the intraoperative decisions of surgical staging at our institution, and such guidelines may be referenced by the institutions with sufficient gynecologic pathology expertise.

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