scholarly journals Cytotoxic Effects of Thiazolo[3,2-C]Pyrimidines Against Mcf-7 And Hepg2/C3a Carcinoma Cell Lines

2018 ◽  
Vol 2 (46) ◽  
pp. 237-246 ◽  
Author(s):  
Arzu Birinci Yıldırım ◽  
Esra Mutlu ◽  
Muhammet Yıldırım
Keyword(s):  
Cell Lines ◽  
Carcinoma Cell ◽  
Cytotoxic Effects ◽  
Carcinoma Cell Lines ◽  
Mcf 7

Cytotoxic Effects of the Therapeutic Radionuclide Rhenium-188 Combined with Taxanes in Human Prostate Carcinoma Cell Lines

2017 ◽  
Vol 32 (1) ◽  
pp. 16-23 ◽  
Author(s):  
Rogier Lange ◽  
Rob ter Heine ◽  
Wessel N. van Wieringen ◽  
Adrienne M. Tromp ◽  
Mayke Paap ◽  
...  
Keyword(s):  
Cell Lines ◽  
Prostate Carcinoma ◽  
Carcinoma Cell ◽  
Human Prostate ◽  
Cytotoxic Effects ◽  
Carcinoma Cell Lines ◽  
Human Prostate Carcinoma ◽  
Prostate Carcinoma Cell

Anticancer Activity of Some Bisbenzimidazoles

2011 ◽  
Vol 66 (9-10) ◽  
pp. 465-470 ◽  
Author(s):  
İlhan Işıkdağ ◽  
Yusuf Özkay ◽  
Zerrin İncesu ◽  
Gülşen Akalın
Keyword(s):  
Anticancer Activity ◽  
Cell Lines ◽  
Topoisomerase I ◽  
Carcinoma Cell ◽  
Dna Topoisomerase ◽  
Carcinoma Cell Lines ◽  
Activity Screening ◽  
Breast Carcinoma Cell Lines ◽  
Ht 29 ◽  
Mcf 7

The discovery of DNA topoisomerases has added a new dimension to the study of anticancer drugs. Bisbenzimidazole derivatives are important compounds known as DNA topoisomerase I inhibitors. In the present study, some symmetrical bisbenzimidazole derivatives were synthesized and investigated for their anticancer activity. Anticancer activity screening was applied on HT-29 (colon carcinoma) and MCF-7 (breast carcinoma) cell lines by investigation of cytotoxicity, analysis of DNA synthesis, and DNA fragmentation assays. One of the seven compounds tested showed signifi cant cytotoxicity in both cell lines and caused DNA degradation in the HT-29 cell line.

Antiproliferative activity of lignans against the breast carcinoma cell lines MCF 7 and BT 20

2011 ◽  
Vol 285 (4) ◽  
pp. 1145-1151 ◽  
Author(s):  
Sibylle Abarzua ◽  
Tatsuo Serikawa ◽  
Marlen Szewczyk ◽  
Dagmar-Ulrike Richter ◽  
Birgit Piechulla ◽  
...  
Keyword(s):  
Breast Carcinoma ◽  
Cell Lines ◽  
Antiproliferative Activity ◽  
Carcinoma Cell ◽  
Carcinoma Cell Lines ◽  
Breast Carcinoma Cell Lines ◽  
Mcf 7
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