Synthesis and characterization of magnetite nanoparticles modified with PEG-based amphiphilic copolymers

2012 ◽  
Vol 1386 ◽  
Author(s):  
Ryo Kasuya ◽  
Teppei Kikuchi ◽  
Jeyadevan Balachandran ◽  
Yutaka Tai
Keyword(s):  
Oleic Acid ◽  
Magnetite Nanoparticles ◽  
Average Diameter ◽  
Magnetic Suspension ◽  
Amphiphilic Copolymers ◽  
Buffer Solution ◽  
Cross Linker ◽  
Surface Modified ◽  
Glycol Methyl Ether

ABSTRACTAn aqueous magnetic suspension was prepared by dispersing amphiphilic co-polymer (ACP) coated monodispersed magnetite nanoparticles (MNPs) synthesized through thermal decomposition of iron(III) acetylacetonate in a mixture of oleic acid and oleylamine. ACP composed of poly (maleic anhydride-alt-1-octadecene) and polyethylene glycol methyl ether was applied to disperse MNPs in water and buffer solution. The average diameter of MNPs increased from 6.6 to 12.5 nm with increasing reaction temperature from 200 to 250°C. Infrared spectra and elemental analysis revealed that the surface modified MNPs contain carboxyl groups originated from oleic acid and ACP. The conjugation of MNPs and bovine serum albumin (BSA) antibody was examined. As a result, the as-synthesized MNPs adsorbed BSA antibody effectively than the surface modified MNPs: the BSA antibody adsorption decreased with increasing cross-linker concentration.

scholarly journals Synthesis of Magnetite Nanoparticles by Top-Down Approach from a High Purity Ore

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Gayan Priyadarshana ◽  
Nilwala Kottegoda ◽  
Atula Senaratne ◽  
Ajith de Alwis ◽  
Veranja Karunaratne
Keyword(s):  
Oleic Acid ◽  
Magnetite Nanoparticles ◽  
High Purity ◽  
Magnetic Domain ◽  
Analysis Data ◽  
X Ray Diffraction ◽  
Top Down ◽  
Coated Nanoparticles ◽  
Natural Iron ◽  
Surface Modified

This study attempts to synthesize magnetite nanoparticles from a high purity natural iron oxide ore found in Panvila, Sri Lanka, following a novel top-down approach. Powder X-Ray diffraction, elemental analysis, and chemical analysis data confirmed the ore to be exclusively magnetite with Fe2+ : Fe3+ratio of 1 : 2. Surface modified magnetite nanoparticles were synthesized by destructuring of this ore using a top-down approach in the presence of oleic acid. These oleic acid coated nanoparticles were further dispersed in ethanol resulting in stable nanomagnetite dispersion. Interestingly, the nanoparticles demonstrated a spherical morphology with a particle size ranging from 20 to 50 nm. Magnetic force microscopic data was used to confirm the topography of the nanoparticles and to study the magnetic domain structure.

Synthesis and Structural Characterization of Surface-Modified TiO2

2010 ◽  
Vol 129-131 ◽  
pp. 154-158 ◽  
Author(s):  
Bao Wei Hao ◽  
Yuan Li ◽  
Shi Zhao Wang
Keyword(s):  
Titanium Dioxide ◽  
Oleic Acid ◽  
Structural Characterization ◽  
Sol Gel ◽  
Tetrabutyl Titanate ◽  
Nano Structure ◽  
Gel Method ◽  
Surface Modified ◽  
Nano Titanium Dioxide

oleic acid-modified nano-titanium dioxide were synthesized by Oleic acid and tetrabutyl titanate via the sol-gel method, and characterized by IR TEM TG-DT A and XPS. Comparison with the data of the IR, the combination of carboxyl is chelating with Ti atoms. Based on the analysis of IR, TG-DTA and XPS, this paper suggests a model about the oleic acid-modified titanium dioxide nano-structure, and to provide a basis for future applications.

Biopolymers with Medical Applications Optimized method for obtaining chitosan-based delivery systems

2018 ◽  
Vol 69 (7) ◽  
pp. 1756-1759 ◽  
Author(s):  
Luminita Confederat ◽  
Iuliana Motrescu ◽  
Sandra Constantin ◽  
Florentina Lupascu ◽  
Lenuta Profire
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Average Diameter ◽  
Delivery Systems ◽  
Cross Linking ◽  
Low Molecular Weight ◽  
Polymeric Systems ◽  
Chitosan Microparticles ◽  
Degree Of Swelling

The aim of this study was to optimize the method used for obtaining microparticles based on chitosan � a biocompatible, biodegradable, and nontoxic polymer, and to characterize the developed systems. Chitosan microparticles, as drug delivery systems were obtained by inotropic gelation method using pentasodiumtripolyphosphate (TPP) as cross-linking agent. Chitosan with low molecular weight (CSLMW) in concentration which ranged between 0.5 and 5 %, was used while the concentration of cross-linking agent ranged between 1 and 5%. The characterization of the microparticles in terms of shape, uniformity and adhesion was performed in solution and dried state. The size of the microparticles and the degree of swelling were also determined. The structure and the morphology of the developed polymeric systems were analyzed by Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM).The average diameter of the chitosan microparticles was around 522 �m. The most stable microparticles were obtained using CSLMW 1% and TPP 2% or CSLMW 0.75%and TPP 1%. The micropaticles were spherical, uniform and without flattening. Using CSLMW in concentration of 0.5 % poorly cross-linked and crushed microparticles have been obtained at all TPP concentrations. By optimization of the method, stable chitosan-based micropaticles were obtained which will be used to develop controlled release systems for drug delivery.

Isolasi Dan Karakterisasi Bentonit Alam Menjadi Nanopartikel Monmorillonit

2018 ◽  
Vol 3 (1) ◽  
pp. 12 ◽  
Author(s):  
Zaimahwati Zaimahwati ◽  
Yuniati Yuniati ◽  
Ramzi Jalal ◽  
Syahman Zhafiri ◽  
Yuli Yetri
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Particle Size ◽  
Surface Morphology ◽  
Average Diameter ◽  
Particle Size Analyzer ◽  
Ft Ir ◽  
Scanning Electron ◽  
Sedimentation Processes

<p>Pada penelitian ini telah dilakukan isolasi dan karakterisasi bentonit alam menjadi nanopartikel montmorillonit. Bentonit alam yang digunakan diambil dari desa Blangdalam, Kecamatan Nisam Kabupaten Aceh Utara.  Proses isolasi meliputi proses pelarutan dengan aquades, ultrasonic dan proses sedimentasi. Untuk mengetahui karakterisasi montmorillonit dilakukan uji FT-IR, X-RD dan uji morfologi permukaan dengan Scanning Electron Microscopy (SEM). Partikel size analyzer untuk menganalisis dan menentukan ukuran nanopartikel dari isolasi bentonit alam. Dari hasil penelitian didapat ukuran nanopartikel montmorillonit hasil isolasi dari bentonit alam diperoleh berdiameter rata-rata 82,15 nm.</p><p><em>In this research we have isolated and characterized natural bentonite into montmorillonite nanoparticles. Natural bentonite used was taken from Blangdalam village, Nisam sub-district, North Aceh district. The isolation process includes dissolving process with aquades, ultrasonic and sedimentation processes.  The characterization of montmorillonite, FT-IR, X-RD and surface morphology test by Scanning Electron Microscopy (SEM). Particle size analyzer to analyze and determine the size of nanoparticles from natural bentonite insulation. From the research results obtained the size of montmorillonite nanoparticles isolated from natural bentonite obtained an average diameter of 82.15 nm.</em></p>

Formulation and Characterization of Oleic Acid Magnetic PEG PLGA Nanoparticles for Targeting Glioblastoma Multiforme

2021 ◽  
pp. 167970
Author(s):  
Khushboo Jani ◽  
Neeraj Kaushal ◽  
Mostafa Sadoqi ◽  
Gen Long ◽  
Zhe-Sheng Chen ◽  
...  
Keyword(s):  
Oleic Acid ◽  
Glioblastoma Multiforme ◽  
Plga Nanoparticles

scholarly journals Synthesis and Characterization of a Bioconjugate Based on Oleic Acid and L-Cysteine

Polymers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 1791
Author(s):  
Marco Vizcarra-Pacheco ◽  
María Ley-Flores ◽  
Ana Mizrahim Matrecitos-Burruel ◽  
Ricardo López-Esparza ◽  
Daniel Fernández-Quiroz ◽  
...  
Keyword(s):  
Oleic Acid ◽  
Materials Science ◽  
Critical Micellar Concentration ◽  
Synthesis And Characterization ◽  
New Materials ◽  
Visible Spectroscopy ◽  
Amide Bonds ◽  
Transmission Electron ◽  
Self Assembled

One of the main challenges facing materials science today is the synthesis of new biodegradable and biocompatible materials capable of improving existing ones. This work focused on the synthesis of new biomaterials from the bioconjugation of oleic acid with L-cysteine using carbodiimide. The resulting reaction leads to amide bonds between the carboxylic acid of oleic acid and the primary amine of L-cysteine. The formation of the bioconjugate was corroborated by Fourier transform infrared spectroscopy (FTIR), Raman spectroscopy, and nuclear magnetic resonance (NMR). In these techniques, the development of new materials with marked differences with the precursors was confirmed. Furthermore, NMR has elucidated a surfactant structure, with a hydrophilic part and a hydrophobic section. Ultraviolet-visible spectroscopy (UV-Vis) was used to determine the critical micellar concentration (CMC) of the bioconjugate. Subsequently, light diffraction (DLS) was used to analyze the size of the resulting self-assembled structures. Finally, transmission electron microscopy (TEM) was obtained, where the shape and size of the self-assembled structures were appreciated.

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