Adenoid cystic carcinoma of the uterine cervix

2012 ◽  
Vol 153 (11) ◽  
pp. 435-437
Author(s):  
Péter Sámuel Nagy ◽  
Zoltán Tóth ◽  
Péter Gőcze ◽  
László Ádám
Keyword(s):  
Cervical Cancer ◽  
Adenoid Cystic Carcinoma ◽  
Rare Disease ◽  
Uterine Cervix ◽  
Poor Prognosis ◽  
Stage Iiib ◽  
Cancer Stage ◽  
Adenoid Cystic ◽  
Irradiation Therapy ◽  
History Of

This report presents the history of a 35-year-old patient with adenoid cystic cervical cancer stage IIIB. Adenoid cystic carcinoma of the uterine cervix is a rare disease with poor prognosis. Following irradiation therapy, the patient was declared tumor free, and 20 years after diagnosis and treatment, she has no pathological signs or symptoms. Orv. Hetil., 2012, 153, 435–437.

Case Report: Coexistence of Adenoid Cystic Carcinoma and Adenoid Basal Carcinoma in the Uterine Cervix

2020 ◽  
Vol 154 (Supplement_1) ◽  
pp. S44-S45
Author(s):  
T T Tran ◽  
R Bhuyan ◽  
S Peng
Keyword(s):  
Adenoid Cystic Carcinoma ◽  
Tumor Cells ◽  
Uterine Cervix ◽  
Poor Prognosis ◽  
Histopathological Examination ◽  
Punch Biopsy ◽  
Good Prognosis ◽  
Positive Staining ◽  
Invasive Squamous Cell Carcinoma ◽  
Adenoid Cystic

Abstract Introduction/Objective Adenoid cystic carcinoma (ACC) and adenoid basal carcinoma (ABC) are very rare tumors, accounting for less than 1% of all cervical adenocarcinomas. ACC is an aggressive neoplasm and has poor prognosis while ABC has a favorable prognosis. Coexistence of ACC or ABC and squamous intraepithelial lesion/invasive squamous cell carcinoma in the uterine cervix has been reported in the literature; however, coexistence of ACC and ABC in the uterine cervix is very rare. Methods Case presentation: Here we present a case of coexistence ACC and ABC in a 66-year-old woman who suffered from heavy bloody vaginal discharge for one year with weight fluctuations. The cervical exam and CT scan showed a friable mass at the uterine cervix, measuring up to 5.5 cm, and cervical mass punch biopsy was performed. Histopathological examination of the specimen revealed an intact nonkeratinizing stratified squamous epithelium overlying proliferation of nests punctuated by small round spaces, resembling cribriform pattern in the stroma. The tumor cells were small and basaloid with hyperchromatic nuclei and scant cytoplasm. Palisading of tumor cells at the peripheral of the tumor nests were observed in some areas. Mitotic figures and necrosis were not seen. Immunohistochemical stains were performed and showed two distinct patterns of ACC and ABC. ACC tumor cells were positive for CD117, focally positive for CAM5.2 and S100, and negative for p63. ABC tumor cells were positive for p63 and EMA and negative for CD117 and S100. Both ACC and ABC components were positive for p16, Sox 10, BCL-2 and vimentin and negative for CK7, p40, CEA and ER. PAS stain showed positive staining in the basement membrane-like material in ACC component. A final pathologic diagnosis of coexistence of ACC and ABC of the uterine cervix were made. Conclusion Literature review revealed that this was an exceedingly rare case of coexistence of ACC and ABC in the uterine cervix. It is extremely important to correctly diagnose ACC and ABC as there is very poor prognosis in the former and good prognosis in the latter.

Adenoid Cystic Carcinoma of Lacrimal Gland

JMS SKIMS ◽  
2012 ◽  
Vol 15 (1) ◽  
pp. 76-77
Author(s):  
Mohd Athar ◽  
K S Sodhi ◽  
S Kala ◽  
R K Maurya ◽  
S Chauhan ◽  
...  
Keyword(s):  
Local Recurrence ◽  
Natural History ◽  
Adenoid Cystic Carcinoma ◽  
Salivary Glands ◽  
Hard Palate ◽  
Clinical Course ◽  
Fatal Outcome ◽  
Minor Salivary Glands ◽  
Adenoid Cystic ◽  
History Of

Adenoid cystic carcinoma is a relatively uncommon tumour of salivary, glands and is characterised by a prolonged clinical course and a fatal outcome. It was first described as `cylindroma' by Billroth in 1859. Half of these tumors occur in glandular tissues other than the major salivary glands; principally in the hard palate, but they can also arise in the tongue and minor salivary glands. Unusual locations include the external auditory canal, nasopharynx, lacrimal glands, breast, vulva, esophagus, cervix and Cowper glands. The long natural history of this tumor and its tendency for local recurrence are well known. JMS 2012;15(1):76-77.

Adenoid cystic carcinoma of the labium oris with rare metastasis to the pleural cavity

2021 ◽  
Vol 14 (1) ◽  
pp. e237622
Author(s):  
Osama Mosalem ◽  
Anas Alsara ◽  
Fawzi Abu Rous ◽  
Borys Hrinczenko
Keyword(s):  
Side Effects ◽  
Adenoid Cystic Carcinoma ◽  
Pleural Cavity ◽  
Epigastric Pain ◽  
Asian Woman ◽  
Upper Lip ◽  
Adenoid Cystic ◽  
History Of ◽  
The Right

A 57-year-old Southeast Asian woman with a remote history of adenoid cystic carcinoma (ACC) of the right labium superius oris (upper lip) presented to the hospital with vague epigastric pain. On workup, she was found to have multiple pleural nodules. Histopathology confirmed the diagnosis of metastatic ACC. After 8 months of active surveillance, evidence of disease progression was found and the patient was started on pembrolizumab. Follow-up after starting pembrolizumab showed stable disease with no significant side effects.

Adenoid Cystic Carcinoma With Sialolithiasis of the Left Submandibular Gland: A Case Report and Literature Review

2018 ◽  
Vol 27 (3) ◽  
pp. 305-310 ◽  
Author(s):  
Satoru Miyabe ◽  
Kenichiro Ishibashi ◽  
Kosuke Saida ◽  
Yukio Fujiyoshi ◽  
Hideo Fukano ◽  
...  
Keyword(s):  
Adenoid Cystic Carcinoma ◽  
Submandibular Gland ◽  
Surgical Specimen ◽  
Adenoid Cystic ◽  
History Of ◽  
Supraomohyoid Neck Dissection ◽  
Additional Procedure ◽  
Long Term Prognosis ◽  
Attending Physician

Adenoid cystic carcinoma is one of the most common salivary gland malignancies with poor long-term prognosis, but the coexistence of sialoliths is extraordinarily rare. In this article, we report a case of 30-year-old woman with a history of submandibular area swelling with intermittent pain increasing during mealtimes that had led her attending physician to diagnose a sialolith in the left submandibular gland on a radiograph 10 years before. However, the surgical specimen proved to be an adenoid cystic carcinoma accompanied with a sialolith. Histopathologically, the submandibular gland was displaced with a fibrous granulation tissue containing a small cribriform carcinoma invading the extracapsular region of the gland. We performed fluorescence in situ hybridization examination with an MYB-NFIB fusion probe of the lesion, with positive results. The patient underwent a supraomohyoid neck dissection as additional procedure because of the possibility of the extracapsular cancer nest remaining around the submandibular gland, but she remains well and disease free 11 years after the first operation.

scholarly journals Adenoid cystic carcinoma of external auditory canal: A rare disease

2021 ◽  
pp. 1-8
Author(s):  
Abdul Basit Vardag ◽  
Muhammad Hassan Danish ◽  
Muhammad Sohail Awan ◽  
Muhammad Usman Tariq ◽  
Omaima Anis Bhatti ◽  
...  
Keyword(s):  
Adenoid Cystic Carcinoma ◽  
Neck Dissection ◽  
Rare Disease ◽  
External Auditory Canal ◽  
Squamous Cell Carcinomas ◽  
Rare Occurrence ◽  
Limited Data ◽  
Aggressive Approach ◽  
Adenoid Cystic

Abstract External auditory canal, like other epithelialized surfaces is predisposed to malignancies such as Squamous cell carcinomas (SCC), melanomas and adenocarcinomas. In this background, malignancies like adenoid cystic carcinoma (ACC) are a rare occurrence and need to be thoroughly evaluated both locally and for distant extension. The malignancy needs to be addressed with an aggressive approach surgically with adequate marginal clearance. The role of radiation is debatable considering the outcomes in the limited data. Here we present a case of a 35-year-old female who presented with otalgia and otorrhea associated a mass in the external auditory canal. After biopsy and imaging, a diagnosis of adenoid cystic carcinoma was made, and the patient was managed accordingly. Keywords: Adenoid cystic carcinoma, External auditory canal, Neck dissection Continuous...

scholarly journals Management of cervical cancer stage Ib1 with poor prognosis during pregnancy: two

2012 ◽  
Vol 4 ◽  
pp. 291-295 ◽  
Author(s):  
Maja Kufelnicka-Babout ◽  
Dorota Kolasa-Zwierzchowska ◽  
Grzegorz Stachowiak ◽  
Małgorzata Zielińska ◽  
Hanna Romanowicz-Makowska ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Poor Prognosis ◽  
Cancer Stage

Cyclooxygenase-2 expression in an adenoid cystic carcinoma of the uterine cervix

2001 ◽  
Author(s):  
O. Ishiko ◽  
T. Sumi ◽  
H. Yoshida ◽  
O. Tokuyama ◽  
K. Wakasa ◽  
...  
Keyword(s):  
Adenoid Cystic Carcinoma ◽  
Uterine Cervix ◽  
Cyclooxygenase 2 ◽  
Adenoid Cystic

scholarly journals Adenoid Cystic Carcinoma of the Lacrimal Gland in a 45 Years Old Male: Case Report and Review of Literature

2019 ◽  
Vol 9 (1) ◽  
pp. 49-53
Author(s):  
Akhlaque Hossain Khan ◽  
Nazmin Ahmed ◽  
Narendra Shalike ◽  
Abul Bashar Md Abdul Matin ◽  
Firoj Ahmed Al Amin ◽  
...  
Keyword(s):  
Adenoid Cystic Carcinoma ◽  
Lacrimal Gland ◽  
Perineural Invasion ◽  
Adult Population ◽  
Treatment Options ◽  
Current Treatment ◽  
Adenoid Cystic ◽  
History Of ◽  
Lacrimal Fossa ◽  
Pathologic Analysis

Adenoid cystic carcinoma (ACC) is a rare malignant tumor that can manifests as proptosis in adult population. They account for 1.6% of all orbital tumors. Despite their rarity, they are the second most frequent epithelial neoplasms occurring in the lacrimal gland after pleomorphic adenomas. This kind of tumors are commonly occur in the salivary glands but can metastasize to lung, breast ,brain and sinuses in hematogenous route.We describe a patient who presented with protrusion of right eyeball, developing over 8 years with history of intermittent watery discharge for 4 years. His magnetic resonance imaging showed a retrobulbarextraconal soft tissue lesion around the lacrimal fossa with invasion and erosion of the adjacent bone. The patient underwent right sided orbito-pterional craniotomy and gross total removal of tumor. Pathologic analysis showed neoplastic cells in a predominantly cribriform pattern with features of perineural invasion and diagnosed as a case adenoid cystic carcinoma of the lacrimal gland. We review the incidence, clinical features, radiographic and histopathologic features of these rare, aggressive malignancies along with current treatment options with reference to the relevant literatures. Bang. J Neurosurgery 2019; 9(1): 49-53

HPV-negative carcinoma of the uterine cervix: a distinct type of cervical cancer with poor prognosis

2014 ◽  
Vol 122 (1) ◽  
pp. 119-127 ◽  
Author(s):  
L Rodríguez-Carunchio ◽  
I Soveral ◽  
RDM Steenbergen ◽  
A Torné ◽  
S Martinez ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Uterine Cervix ◽  
Poor Prognosis ◽  
Distinct Type

Histological changes during progression of adenoid cystic carcinoma

1992 ◽  
Vol 106 (11) ◽  
pp. 1016-1020 ◽  
Author(s):  
Yuzo Yamamoto ◽  
Tetsuro Saka ◽  
Kazuo Makimoto ◽  
Hiroaki Takahashi
Keyword(s):  
Adenoid Cystic Carcinoma ◽  
Poor Prognosis ◽  
Early Stage ◽  
Primary Tumour ◽  
Reverse Direction ◽  
Histological Changes ◽  
Histological Features ◽  
Metastatic Lesions ◽  
Adenoid Cystic ◽  
Histological Transformation

AbstractEight cases of adenoid cystic carcinoma were reviewed to determine whether and how the histological features of the tumour vary with the progress of the disease. The tumours were classified by their histological patterns as tubular, cribriform, trabecular or solid. The relative amount of each pattern seen in routine light microscopic sections was calculated histomorphometrically and compared in the primary tumour and recurrent and/or metastatic lesions in the same case. In the early stage, the tubular pattern predominated. Later, the highest percentage shifted to the cribriform, then to the trabecular and finally, in the late stage, to the solid pattern. There was no reverse direction of histological transformation from the solid to the tubular pattern. These results may help to explain previous reports that the tubular pattern usually represents a favourable prognosis, the solid pattern a poor prognosis and the cribriform pattern an intermediate prognosis.

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