The dynamics of humoral protection factors in broilers under the conditions of probiotic preparations application
The health of farm poultry depends on the balance between normal and potentially pathogenic intestinal microflora. Any changes in this equilibrium are accompanied by functional impairments, which, in turn, lead to a decrease in productivity. The use of probiotics helps to avoid imbalance of intestinal microflora and death of young animals. In this connection, it is relevant to study the effects of probiotic drugs to improve the vitality and immune function of the poultry. The purpose of the research was to clarify the effect of BPS-44 and different amounts of yeast Saccharomyces cerevisiae on the activity of the humoral level of natural resistance in chicken broilers. Experiments were carried out on broiler chicks-308 grown in the Fedyuk M farm in the Zolochiv district of Lviv oblast. The maintenance of the chickens was cellular with free access to feed and water. Technological parameters of broiler cultivation (temperature and light regime) were in accordance with the norms of ONTP-2005. Experiments were conducted in 4 groups of broiler chickens of 100 chicks in each according to the scheme: the control group was fed with the standard feed (SC) according to the existing norms recommended for the ROSS-308 cross; the experimental group I in addition to the SC received a probiotic BPS-44 (registration certificate No. 2154-04-0254-06 dated November 24, 2006), based on the production strain of bacteria Bacillus subtilis ssp. subtilis 44-p, dose 0.21 g/kg, the experimental group II – 1% yeast Saccharomyces cerévisiae; the experimental group III of chickens – 2% yeast Saccharomyces cerévisiae. Blood was taken from chickens in order to carry out immunological research at different age intervals: 11, 27, 34 and 41 days of age. Blood serum was determined by bactericidal and lysozyme activity and the content of circulating immune complexes. The stimulatory effect of BPS-44 and yeast Saccharomyces cerеvisiae in the composition of mixed fodder for broiler chickens on the dynamics of the formation of humoral protection factors in the bird organism was established. At the same time, in the conditions of use of yeast Saccharomyces cerэvisiae in the composition of mixed fodder, a higher level of indices of the humoral level of non-specific resistance was recorded, than the preparation BPS-44.