scholarly journals ОСНОВНІ НЕВРОЛОГІЧНІ СИМТОМИ ТА ЇХ ПОШИРЕННЯ У СОБАК

2016 ◽  
Vol 18 (3(71)) ◽  
pp. 240-243
Author(s):  
V. Fedorovych ◽  
L. Slivinska ◽  
N. Fedorovych
Keyword(s):  
Nervous System ◽  
Pathological Process ◽  
Neurological Symptoms ◽  
Nervous System Diseases ◽  
Anatomical Localization ◽  
Neurological Research ◽  
The Brain

As a result of the ambulatory reception it was investigated 12233 animals, of which 5653 (46.2%) were dogs. In the neurological research it had shown the symptoms of the nervous system damage in 653 dogs (11.5%). In particular it was found that paresis and paralysis (23.4%) were the most common neurological symptoms in dogs. Number of animals with inclination of head, ataxia, myoclonus and epileptiform state was respectively 19.8; 14.7; 11.7 and 10.5%. The manifestations of the nervous system damage as nystagmus, tremor and lameness were registered in accordance with 8.3; 4.4 and 4.1% of sick dogs. The least number of dogs were with a disorder of vision (2,8%) and hearing (0,3%), which was associated with the pathology of the nervous system. The above mentioned symptoms of the nervous system diseases do not occur as a symptom, but it was marked their combination – syndromes. The conducted neurological research makes it possible to establish the location of the pathological process in the departments of nervous system (neurons anatomical localization).As a result of the research and the results found that most dogs manifest the symptoms of damage to the brain and spinal mozkupaytiyi. Based on the results of verification of the diagnosis will be made using the methods of visual diagnostics. 

Neurological symptoms of COVID-19

2021 ◽  
Vol 36 (4) ◽  
pp. 285-296
Author(s):  
Adriana Wawer ◽  
Agnieszka Piechal
Keyword(s):  
Nervous System ◽  
Viral Infections ◽  
Harmful Effect ◽  
Neurological Complications ◽  
Neurological Symptoms ◽  
Acute Respiratory Disease ◽  
Neurological Damage ◽  
Impaired Consciousness ◽  
Potential Impact ◽  
The Brain

Objective. Some viral infections can have a harmful effect on the functioning of the nervous system and can even cause serious neurological damage. This work aims to review the results of studies published so far concerning neurological complications in people infected with coronaviruses, especially SARS-CoV-2, and possible mechanisms responsible for nervous system damage. Literature review. Recently, there have been reports that coronaviruses, including SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), cause acute respiratory disease, exhibit neurotropic properties and can also cause neurological symptoms. There are studies published showing that these viruses may penetrate to the brain and cerebrospinal fluid. Conclusions. Coronaviruses are still poorly understood, so it seems important to study the potential impact of SARS-CoV-2 infections on the nervous system. It seems appropriate that patients infected with SARS-CoV-2 should be early evaluated for neurological symptoms, including headache and impaired consciousness.

scholarly journals Exosomes as cell-derivative carriers in the diagnosis and treatment of central nervous system diseases

2021 ◽  
Author(s):  
Gayatri Gopal Shetgaonkar ◽  
Shirleen Miriam Marques ◽  
Cleona E. M. DCruz ◽  
R. J. A. Vibhavari ◽  
Lalit Kumar ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Brain Parenchyma ◽  
Brain Diseases ◽  
Nervous System Diseases ◽  
Central Nervous System Diseases ◽  
Diagnosis And Prognosis ◽  
Potential Biomarker ◽  
Treatment And Diagnosis ◽  
The Brain

AbstractExosomes are extracellular vesicles with the diameter ranging from 50 to 100 nm and are found in different body fluids such as blood, cerebrospinal fluid (CSF), urine and saliva. Like in case of various diseases, based on the parent cells, the content of exosomes (protein, mRNA, miRNA, DNA, lipids and metabolites) varies and thus can be utilized as potential biomarker for diagnosis and prognosis of the brain diseases. Furthermore, utilizing the natural potential exosomes to cross the blood–brain barrier and by specifically decorating it with the ligand as per the desired brain sites therapeutics can be delivered to brain parenchyma. This review article conveys the importance of exosomes and their use in the treatment and diagnosis of brain/central nervous system diseases. Graphical abstract

Role of neurological research in rehabilitation after central nervous system diseases

1996 ◽  
Vol 17 (3) ◽  
pp. 255-256
Author(s):  
F. Mari ◽  
L. Provinciali ◽  
Luigi Tesio ◽  
Chiara Gamba ◽  
Angelo Capelli ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Nervous System Diseases ◽  
Central Nervous System Diseases ◽  
Neurological Research

scholarly journals Tembusu Virus entering the central nervous system caused nonsuppurative encephalitis without disrupting the blood-brain barrier

2021 ◽  
Author(s):  
Sheng Yang ◽  
Yufei Huang ◽  
Yonghong Shi ◽  
Xuebing Bai ◽  
Ping Yang ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Blood Brain Barrier ◽  
Neurological Symptoms ◽  
Brain Barrier ◽  
Poultry Industry ◽  
Blood Brain ◽  
The Central Nervous System ◽  
Tembusu Virus ◽  
The Brain

Tembusu Virus (TMUV) is an emerging and re-emerging zoonotic pathogen that adversely affects poultry industry in recent years. TMUV disease is characterized by nonsuppurative encephalitis in ducklings. The duckling infection model was established to study the mechanism of TMUV crossing the blood-brain barrier (BBB) into the central nervous system (CNS). Here, we showed that no obvious clinical symptoms and enhancement of BBB permeability occurred at the early stage of infection (3∼5 dpi). While simultaneously virus particles were observed by transmission electron microscopy in the brain, inducing the accumulation of inflammatory cytokines. Neurological symptoms and disruption of BBB appeared at the intermediate stage of infection (7∼9 dpi). It was confirmed that TMUV could survive and propagate in brain microvascular endothelial cells (BMECs), but did not affect the permeability of BBB in vivo and in vitro at an early date. In conclusion, TMUV enters the CNS then causes encephalitis, and finally destruct the BBB, which may be due to the direct effect of TMUV on BMECs and the subsequent response of “inflammatory storm”. IMPORTANCE The TMUV disease has caused huge losses to the poultry industry in Asia, which is potentially harmful to public health. Neurological symptoms and their sequelae are the main characters of this disease. However, the mechanism of how this virus enters the brain and causes encephalitis is unclear. In this study, we confirmed that the virus entered the CNS and then massively destroyed BBB and the BBB damage was closely associated with the subsequent outbreak of inflammation. TMUV may enter the CNS through the transcellular and “Trojan horse” pathways. These findings can fill the knowledge gap in the pathogenesis of TMUV-infected poultry and be benefit for the treatment of TMUV disease. What’s more, TMUV is a representative to study the infection of avian flavivirus. Therefore, our studies have significances both for understanding of the full scope of mechanisms of TMUV and other flavivirus infection, and conceivably, for therapeutics.

scholarly journals The clinical manifestations of nervous system mesenchyme syphilis

2002 ◽  
Vol 1 (2) ◽  
pp. 77-82
Author(s):  
T. A. Valikova ◽  
V. M. Alifirova ◽  
I. M. Fyodorova ◽  
N. Yu. Paimursina
Keyword(s):  
Nervous System ◽  
Progressive Disease ◽  
Clinical Manifestations ◽  
Pathological Process ◽  
Acute Stage ◽  
Pathologic Process ◽  
First Case ◽  
Brain Substance ◽  
Chronic Progressive Disease ◽  
The Brain

Nervous system syphilis — neurosyphilis (NS) belongs to rather rare diseases. According to the different authors data available it comes to about 1% of the nervous system organic disturbances and develops by 5—10% syphilous patients not having been treated in the acute stage of the pathological process. The syphilitic disturbance of the nervous system is a chronic progressive disease caused by the pale spirochaeta. The nervous system disturbance occurs basically in two ways: secondary one, because of brain shells, vessels, gummatous manifestations involving in the pathologic process; or primary one, when the causative agent affects directly the brain substance. In the first case syphilis is called rnesodermic or early one; in the second case — parenchymatous or late, primary one. In the article the analysis of two clinical cases of mesenchyme neurosyphilis is carried out: latent neurosyphilis and syphilitic meningomyelitis. Neurosyphilis classification is applied to clinical manifestatons of syphilitic arachnoiditis and vasculitis are described. The methods of specific and nonspecific therapy of mesenchyme syphilis are stated in detail.

scholarly journals Human Chronic Necrotizing Granulomatous Meningoencephalitis: A Novel Case Report

2018 ◽  
Vol 10 (3) ◽  
pp. 302-308
Author(s):  
Alexus P. Taddonio ◽  
Eric J. Veloso ◽  
Kelly J. Baldwin
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Case Report ◽  
Female Patient ◽  
Treatment Options ◽  
Neurological Symptoms ◽  
Nervous System Diseases ◽  
Central Nervous System Diseases ◽  
New Onset

Necrotizing and granulomatous meningoencephalitis are common central nervous system diseases known to affect canines. To date, necrotizing granulomatous meningoencephalitis has yet to be described in humans. Current studies of presumed pathogenesis and possible treatment options have only been described in canines. This is a case report of a 55-year-old female patient who was diagnosed with necrotizing granulomatous meningoencephalitis in the setting of new-onset neurological symptoms without any infectious or malignant source.

Sign in / Sign up

Export Citation Format

Share Document