Role of neurological research in rehabilitation after central nervous system diseases

1996 ◽  
Vol 17 (3) ◽  
pp. 255-256
Author(s):  
F. Mari ◽  
L. Provinciali ◽  
Luigi Tesio ◽  
Chiara Gamba ◽  
Angelo Capelli ◽  
...  
2021 ◽  
Vol 22 (24) ◽  
pp. 13427
Author(s):  
Ivan Emmanuel Ramos-Martínez ◽  
María Carmen Rodríguez ◽  
Marco Cerbón ◽  
Juan Carlos Ramos-Martínez ◽  
Edgar Gustavo Ramos-Martínez

In several central nervous system diseases, it has been reported that inflammation may be related to the etiologic process, therefore, therapeutic strategies are being implemented to control inflammation. As the nervous system and the immune system maintain close bidirectional communication in physiological and pathological conditions, the modulation of inflammation through the cholinergic anti-inflammatory reflex has been proposed. In this review, we summarized the evidence supporting chemical stimulation with cholinergic agonists and vagus nerve stimulation as therapeutic strategies in the treatment of various central nervous system pathologies, and their effect on inflammation.


2019 ◽  
Vol 31 (11) ◽  
pp. 697-714 ◽  
Author(s):  
Jean-Philippe Auger ◽  
Marie-Odile Benoit-Biancamano ◽  
Christian Bédard ◽  
Mariela Segura ◽  
Marcelo Gottschalk

MyD88 signaling modulates the outcome of Streptococcus suis infection


Author(s):  
Wanying Liu ◽  
Xiaodan Bai ◽  
Ao Zhang ◽  
Juanjuan Huang ◽  
Shixin Xu ◽  
...  

2019 ◽  
Vol 73 ◽  
pp. 865-886
Author(s):  
Aleksandra Szewczyk ◽  
Apolonia Witecka ◽  
Anna Kiersztan

According to current knowledge, the number of microorganisms living in our body slightly exceeds the number of our own cells, and most of them occupy the large intestine. New methods for analyzing microorganisms residing in our intestine (intestinal microbiota) enable a better understanding of their metabolic, protective and structural functions as well as complex interactions with the host. The development of microbiota is dynamic, and its composition may change during our lifetime. Many factors can affect the composition of microbiota, such as diet, stress, age, genetic factors and antibiotic therapy. Microbiota-gut-brain communication is bi-directional and is mediated via neuronal, immunological and humoral pathways. This article focuses on gut-brain axis elements, such as the vagus nerve, hypothalamic-pituitary-adrenal axis (HPA), cytokines, neurotransmitters, hormones and intestinal peptides, allowing microbiota to contact with the central nervous system. Moreover, this article shows the mechanisms by which microbiota affects the brain functions related to our behavior, mood and cognitive processes. In addition, the role of microbiota composition disorders in the pathogenesis of central nervous system diseases (such as depression, autism spectrum disorder, schizophrenia, multiple sclerosis, Parkinson’s disease and Alzheimer’s disease) is discussed. This article also focuses on the results from studies in which probiotics have been used as potential therapeutic agents in the treatment of gastrointestinal disorders and also alleviating the symptoms of the central nervous system diseases.


Neuroreport ◽  
2016 ◽  
pp. 1 ◽  
Author(s):  
Xiao-Mei Li ◽  
Hai-Jing Yan ◽  
Yi-Shan Guo ◽  
Dong Wang

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