scholarly journals ГІСТОЛОГІЧНІ ЗМІНИ В ТЕЛЯТ ЗА ГОСТРОГО ПЕРЕБІГУ САЛЬМОНЕЛЬОЗУ

2016 ◽  
Vol 18 (2(66)) ◽  
pp. 122-126
Author(s):  
V. Lisova ◽  
A. Pavlenko ◽  
N. Romanenko
Keyword(s):  
Small Intestine ◽  
Lymph Nodes ◽  
Causative Agent ◽  
Liver Cell ◽  
Blood Cells ◽  
Theoretical Ground ◽  
Toxic Shock ◽  
Histological Changes ◽  
Intestinal Lymph ◽  
Acute Form

The results of study of histological changes in calves by age of 20 – 40 days at acute salmonellosis infection are presented. At a histological research the most expressed changes were registered in the liver, thin intestine and lymphoid organs that contingently reproduction here of the causative agent. At acute form of salmonellosis in calves of this age-grade characteristic histological changes include: submilliar, intralobular, coagulativ, areactive foci of necrosis in a liver; cell granuloma in a liver; the acute diffusive serous-catarrhal enteritis with a hemorrhagic accent; serous lymphadenitis of intestinal lymph nodes; the acute diffusive catarrhal abomasitis. Also nonspecific, but constant morphological signs of salmonellosis are hyperplasia Peyer’s patches of a small intestine, intestinal lymph nodes, spleen and dystrophic changes of parenchymal organs.An analysis and theoretical ground of pathogenetic mechanisms of the educed microstructural changes are conducted. It is shown that in pathogenesis of salmonellosis an important role is played bacteriaemia and toxinaemia, which result to the defeat of endothelia of vessels and blood cells with subsequent violation of mechanisms of haemostasis гand development of the infectiously-toxic shock.

scholarly journals Гістоморфологічні зміни в органах і тканинах мурчаків, інфікованих ентеротоксигенними штамами Y. Enterocoliticа

2015 ◽  
pp. 73-83
Author(s):  
Б. В. Борисевич ◽  
В. Г. Скибіцький ◽  
Г. В. Козловська ◽  
А. В. Козловська
Keyword(s):  
Small Intestine ◽  
Lymph Nodes ◽  
Causative Agent ◽  
Guinea Pigs ◽  
Degenerative Changes ◽  
Necrotic Enteritis ◽  
Immune Organs ◽  
Liver And Pancreas ◽  
Histomorphological Changes ◽  
Significant Activation

Викладено результати дослідження гістоморфо-логічних змін органів і тканин мурчаків, інфікованихентеротоксигенними штамами Y. enterocoliticа. Зок-рема встановлено, що найбільше уражається тонкакишка, де виявляють поверхневий некротичний енте-рит. Токсини збудника хвороби, потрапляючи в кров,спричиняють дистрофічні зміни в печінці та підшлун-ковій залозі, спричиняють екстракапілярний серознийгломерулонефрит та дистрофічні зміни епітеліюканальців нирок, а також серозний міокардит. Інфі-кування мурчаків призводить до значної активаціївсіх імунокомпетентних органів організму – тимусу,селезінки, соматичних і вісцеральних лімфовузлів. The results of the study of histomorphological changes in organs and tissues of guinea pigs infected with enterotoxigenic strains of Y. enterocolitica were presented. We established, in particular, the most affected in small intestine, where superficial necrotic enteritis was determined. Toxins are causative agent, getting into the bloodstream cause degenerative changes in the liver and pancreas. And also serous ecstracapillary glomerulonephritis and degenerated changes of epithelial tubules of the kidneys and serous myocarditis were caused. The infecting of guinea pigs leads significant activation of immune organs: thymus, spleen, somatic and visceral lymph nodes.

Experimental transfusion of lymphocytes

1960 ◽  
Vol 198 (5) ◽  
pp. 1014-1018 ◽  
Author(s):  
Roy G. Shorter ◽  
Jesse L. Bollman
Keyword(s):  
Bone Marrow ◽  
Small Intestine ◽  
Lymph Nodes ◽  
Tissue Distribution ◽  
Maximal Activity ◽  
Gradual Decrease ◽  
Thymus Gland ◽  
Intestinal Lymph ◽  
Migratory Process

Lymphocytes, obtained from the intestinal lymph of rats and labeled with radiochromium or radiophosphate, were injected intravenously into rats. Both autogenous and homologous lymphocytes which were motile at the time of injection were used. No appreciable radioactivity became evident in the intestinal lymph until 4 hours after injection, but as much as half of the injected material was recovered in the lymph of the subsequent 24 hours. All the radioactivity disappeared from the blood within a half-hour, and began to reappear within 4 hours to reach maximal activity at about 24 hours. Tissue distribution determined at intervals indicated that 73% of the injected material was in the spleen at one-half hour, and that there was a gradual decrease to 7% by 72 hours. The content in bone marrow decreased from 4.5 to 1.3% at the same time. The thymus gland, lymph nodes, liver and small intestine showed increases over this same period. An active migratory process of lymphocytes is clearly indicated.

scholarly journals Mycobacterial infections in European wild boar (Sus scrofa) in the CzechRepublic during the years 2002 to 2005

2012 ◽  
Vol 51 (No. 5) ◽  
pp. 320-332 ◽  
Author(s):  
I. Trcka ◽  
J. Lamka ◽  
R. Suchy ◽  
M. Kopecna ◽  
V. Beran ◽  
...  
Keyword(s):  
Lymph Nodes ◽  
Wild Boar ◽  
Causative Agent ◽  
Adult Males ◽  
Mycobacterial Infections ◽  
Intestinal Lymph ◽  
Rflp Type ◽  
European Wild Boar ◽  
Faecal Samples ◽  
Gross Lesions

A total of 842 wild boar of differing ages, originating from 29 (37.7%) of the 77 districts in the Czech Republic, were examined during the hunting seasons from 2002 to 2005. Of them, 274 (32.5%) of the animals were wild specimens and 568 (67.5%) from game parks. Out of 786 animals, the following were included in the study: 668 piglets, 61 juveniles, 32 adult males and 25 adult females. A total of 2 704 samples from various tissues and faeces were examined: 309 separately collected faecal samples from 309 (36.7%) animals, 2 332 samples from various tissues and 63 faecal samples from 533 (63.3%) animals. Mycobacteria were isolated from 75 (8.9%) animals from 11 of the districts. Neither a causative agent of bovine tuberculosis, nor any other members of Mycobacterium tuberculosis complex were isolated from any of the animals. From one (0.1%) animal, M. avium subsp. paratuberculosis of IS900 RFLP type A-C10 was isolated from intestinal lymph nodes, which was also isolated within the same district during other studies of cattle and free living ruminants. The causative agent of avian tuberculosis, M. a. avium (IS901+ and IS1245+), was isolated from 7 (0.8%) animals; among them tuberculous lesions were detected in intestinal lymph nodes, with gross tuberculous lesions visible on two animals. The causative agent of avian mycobacteriosis M. a. hominissuis (IS901– and IS1245+) was detected in lymph nodes without gross lesions in one (0.1%) animal. From 45 (5.5%) animals without lesions, atypical mycobacteria of the following nine species were isolated from pulmonary lymph nodes, small and large intestine, intestinal mucosa and faeces: M. fortuitum, M. chelonae, M. scrofulaceum, M. triviale, M. terrae, M. phlei, M. abscessus, M. flavescens, and M. smegmatis. Due to a high density of wild boar and their large migration radius, they can be viewed as a potential source for mycobacterial infections as well as other infectious agents.

scholarly journals Two distinct pools of recirculating T lymphocytes: migratory characteristics of nodal and intestinal T lymphocytes.

1977 ◽  
Vol 145 (2) ◽  
pp. 420-428 ◽  
Author(s):  
R N Cahill ◽  
D C Poskitt ◽  
D C Frost ◽  
Z Trnka
Keyword(s):  
Small Intestine ◽  
T Lymphocytes ◽  
Lymph Nodes ◽  
Thoracic Duct ◽  
Initial Development ◽  
Intestinal Lymph ◽  
Relative Recovery ◽  
Large Numbers ◽  
Intestinal Circulation

A pronounced asymmetry in the recirculation from blood to lymph of resting small recirculating T lymphocytes is described. When 51Cr-labeled small T-recirculating lymphocytes (TRL) from intestinal lymph were infused intravenously their relative recovery in intestinal lymph was about twice that in nodal lymph. In contrast, the relative recovery in nodal lymph of 51Cr-labeled nodal TRL was twice that in intestinal lymph. Intestinal TRL migrated in large numbers through the small intestine. Nodal TRL did not. It is proposed that the pool of recirculating small T lymphocytes consists of two major subdivisions, an intestinal pool and a nodal pool. The nodal circulation comprises small TRL which traverse PCV in all lymph nodes (LN) but not the small intestine. The intestinal circulation comprises small TRL which do not traverse PCV in LN, but which do recirculate through the small intestine from which they pass via afferent lymphatics to the mesenteric LN and subsequently via the thoracic duct into the blood. It is suggested that the intestinal circulation is present in the fetus and that its initial development is independent of extrinsic antigen.

Scanning electron microscopy of erythrophagocytosis by Entamoeba histolytica trophozoites

1992 ◽  
Vol 50 (1) ◽  
pp. 880-881
Author(s):  
Victor Tsutsumi ◽  
Adolfo Martinez-Palomo ◽  
Kyuichi Tanikawa
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Red Blood Cells ◽  
Entamoeba Histolytica ◽  
Causative Agent ◽  
Blood Cells ◽  
Protozoan Parasite ◽  
Complex Phenomenon ◽  
Great Capacity ◽  
Scanning Electron

The protozoan parasite Entamoeba histolytica is the causative agent of amebiasis in man. The trophozoite or motile form is a highly dynamic and pleomorphic cell with a great capacity to destroy tissues. Moreover, the parasite has the singular ability to phagocytize a variety of different live or death cells. Phagocytosis of red blood cells by E. histolytica trophozoites is a complex phenomenon related with amebic pathogenicity and nutrition.

In situ demonstration of migration of dendritic cells released from rat small intestine to mesenteric lymph nodes

2001 ◽  
Vol 120 (5) ◽  
pp. A183-A183
Author(s):  
H KOBAYASHI ◽  
H NAGATA ◽  
S MIURA ◽  
T AZUMA ◽  
H SUZUKI ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Small Intestine ◽  
Lymph Nodes ◽  
Rat Small Intestine ◽  
Mesenteric Lymph Nodes ◽  
Mesenteric Lymph

scholarly journals Culture-Independent Analysis of Indomethacin-Induced Alterations in the Rat Gastrointestinal Microbiota

2006 ◽  
Vol 72 (10) ◽  
pp. 6707-6715 ◽  
Author(s):  
Andrew B. Dalby ◽  
Daniel N. Frank ◽  
Allison L. St. Amand ◽  
Alison M. Bendele ◽  
Norman R. Pace
Keyword(s):  
Small Intestine ◽  
Lymph Nodes ◽  
Small Subunit ◽  
Rrna Genes ◽  
Small Subunit Rrna ◽  
Mesenteric Lymph Nodes ◽  
Gastrointestinal Microbiota ◽  
Mesenteric Lymph ◽  
Independent Analysis ◽  
Culture Independent

ABSTRACT Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly prescribed for a variety of inflammatory conditions; however, the benefits of this class of drugs are accompanied by deleterious side effects, most commonly gastric irritation and ulceration. NSAID-induced ulceration is thought to be exacerbated by intestinal microbiota, but previous studies have not identified specific microbes that contribute to these adverse effects. In this study, we conducted a culture-independent analysis of ∼1,400 bacterial small-subunit rRNA genes associated with the small intestines and mesenteric lymph nodes of rats treated with the NSAID indomethacin. This is the first molecular analysis of the microbiota of the rat small intestine. A comparison of clone libraries and species-specific quantitative PCR results from rats treated with indomethacin and untreated rats revealed that organisms closely related to Enterococcus faecalis were heavily enriched in the small intestine and mesenteric lymph nodes of the treated rats. These data suggest that treatment of NSAID-induced ulceration may be facilitated by addressing the microbiological imbalances.

scholarly journals THE EFFECT OF LYMPHOCYTOSIS INDUCED WITH EMBRYONIC EXTRACT ON THE COURSE OF EXPERIMENTAL TUBERCULOSIS IN RABBITS

1932 ◽  
Vol 56 (2) ◽  
pp. 173-183 ◽  
Author(s):  
Kenneth C. Smithburn
Keyword(s):  
Chick Embryo ◽  
Lymph Nodes ◽  
Blood Cells ◽  
Lymphoid Hyperplasia ◽  
Germinal Centers ◽  
Experimental Tuberculosis ◽  
Embryo Extract ◽  
Chick Embryo Extract ◽  
Tuberculosis In Children ◽  
Immature Cells

1. Chick embryo extract given intravenously did not favorably influence the course of experimental tuberculosis in rabbits, although it did cause lymphocytosis and lymphoid hyperplasia. 2. The tuberculous animals treated with chick embryo extract showed lower values for hemoglobin and red blood cells than tuberculous controls inoculated from the same suspension. 3. Under the conditions of these experiments an increase in the number of young, immature cells in the lymph nodes was accompanied by more extensive tuberculous lesions in the lymph nodes and especially in the germinal centers of the nodes. A possible analogy to lymphatic tuberculosis in children is suggested. 4. The observations of previous investigators on the progression and later regression of lesions in experimental tuberculosis have been confirmed. The distribution, character, and extent of lesions have been studied and are presented in tabular form. 5. The presence and significance of tuberculous thrombi in the lungs are discussed.

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