scholarly journals Comparative Study on Picryl Chloride (PCL)-Induced Contact Dermatitis in Female IQI/Jic and BALB/c Mice

2004 ◽  
Vol 53 (2) ◽  
pp. 89-96 ◽  
Author(s):  
Ji-Youn JUNG ◽  
Junzo SAEGUSA ◽  
Hiroyuki NAKAYAMA ◽  
Kunio DOI
Keyword(s):  
Contact Dermatitis ◽  
Comparative Study ◽  
Picryl Chloride

scholarly journals Nickel, chromium and cobalt: the relevant allergens in allergic contact dermatitis. Comparative study between two periods: 1995-2002 and 2003-2015

2018 ◽  
Vol 93 (1) ◽  
pp. 59-62 ◽  
Author(s):  
Ida Duarte ◽  
Rodolfo Ferreira Mendonça ◽  
Karen Levy Korkes ◽  
Rosana Lazzarini ◽  
Mariana de Figueiredo Silva Hafner
Keyword(s):  
Contact Dermatitis ◽  
Comparative Study ◽  
Allergic Contact Dermatitis ◽  
Nickel Chromium ◽  
Allergic Contact

scholarly journals STUDIES ON THE SENSITIZATION OF ANIMALS WITH SIMPLE CHEMICAL COMPOUNDS

1940 ◽  
Vol 71 (2) ◽  
pp. 237-245 ◽  
Author(s):  
K. Landsteiner ◽  
M. W. Chase
Keyword(s):  
Contact Dermatitis ◽  
Intraperitoneal Injection ◽  
Chemical Compounds ◽  
Route Of Administration ◽  
Necessary Condition ◽  
Skin Sensitization ◽  
Paraffin Oil ◽  
Simple Chemical ◽  
Picryl Chloride ◽  
Dermal Application

A method has been described by which sensitization to a simple chemical, picryl chloride (2:4:6 trinitrochlorobenzene), can be satisfactorily attained by means of intraperitoneal injection of the compound when killed tubercle bacilli suspended in paraffin oil were used as adjuvant. Sensitivity of the contact dermatitis type results therefrom. It follows that although skin sensitization of this type is most easily obtained by dermal application this route of administration is no necessary condition for such sensitivity.

Ultrastructural features of mast cells in picryl chloride (PCL)-induced contact dermatitis in IQI/Jic mice

2003 ◽  
Vol 54 (4) ◽  
pp. 265-271 ◽  
Author(s):  
Ji-Youn Jung ◽  
Akira Yasoshima ◽  
Junzo Saegusa ◽  
Hiroyuki Nakayama ◽  
Kunio Doi
Keyword(s):  
Contact Dermatitis ◽  
Mast Cells ◽  
Picryl Chloride

scholarly journals STUDIES ON THE SENSITIZATION OF ANIMALS WITH SIMPLE CHEMICAL COMPOUNDS

1937 ◽  
Vol 66 (3) ◽  
pp. 337-351 ◽  
Author(s):  
K. Landsteiner ◽  
M. W. Chase
Keyword(s):  
Contact Dermatitis ◽  
Strong Evidence ◽  
Guinea Pigs ◽  
Chemical Properties ◽  
Chemical Compounds ◽  
Protein Conjugates ◽  
Chemical Constitution ◽  
Simple Chemical ◽  
Picryl Chloride ◽  
Cutaneous Administration

It has been shown that by the cutaneous administration of simple chemical compounds in small quantities—2:4:6 trinitrochlorobenzene (picryl chloride) and 2:4 dinitrochlorobenzene, the latter a typical incitant of contact dermatitis in man—it is possible to induce true anaphylactic sensitization in guinea pigs, demonstrable by the intravenous injection of protein conjugates and by the Dale technique, using isolated uterine horns. This furnishes strong evidence for the formation of antigenic conjugates following application of substances of simple chemical constitution. Since the anaphylactic state is induced by the same method of administration that gives rise to cutaneous sensitivity, the assumption would appear justified, when one takes into account the chemical properties of the inciting substances, that the formation of conjugated antigens offers an explanation for the skin effects also. In the experiments with picryl chloride, anaphylactic antibodies, and occasionally precipitins, have been demonstrated. The differences between the cutaneous and anaphylactic types of sensitivity are discussed.

scholarly journals Picryl Chloride-Induced Contact Dermatitis in IQI/Jic Male Mice

2001 ◽  
Vol 14 (3) ◽  
pp. 231-231 ◽  
Author(s):  
Ji-Youn Jung ◽  
Junzo Saegusa ◽  
Koji Uetsuka ◽  
Hiroyuki Nakayama ◽  
Kunio Doi
Keyword(s):  
Contact Dermatitis ◽  
Male Mice ◽  
Picryl Chloride
Sign in / Sign up

Export Citation Format

Share Document