scholarly journals Cardiac death and myocardial lesions in non-stroke SHRSP under specific pathogen-free system.

1981 ◽  
Vol 22 (3) ◽  
pp. 387-393 ◽  
Author(s):  
Hideo UEDA ◽  
Tadahiko MIYAZAKI ◽  
Yoshio SUGANUMA ◽  
Naohiro SAITO ◽  
Yasushi KATO
Keyword(s):  
Cardiac Death ◽  
Specific Pathogen Free ◽  
Free System ◽  
Specific Pathogen ◽  
Myocardial Lesions

scholarly journals Ultrastructural Changes of the Myocardium of SHRSP derived from the parents of Cardiac Death under Specific Pathogen-Free System

1981 ◽  
Vol 22 (3) ◽  
pp. 506-506
Author(s):  
Hideo Ueda ◽  
Tadahiko Miyazaki ◽  
Kinya Hayakawa ◽  
Yoshio Suganuma ◽  
Naohiro Saito ◽  
...  
Keyword(s):  
Cardiac Death ◽  
Ultrastructural Changes ◽  
Specific Pathogen Free ◽  
Free System ◽  
Specific Pathogen

scholarly journals The Heart Failure and Myocardial Changes of SHRSP derived from Non-stroke Parents under Specific Pathogen-free System

1980 ◽  
Vol 21 (4) ◽  
pp. 564-564 ◽  
Author(s):  
Hideo Ueda ◽  
Tadahiko Miyazaki ◽  
Atsushi Sakamoto ◽  
Kinya Hayakawa ◽  
Yoshio Suganuma ◽  
...  
Keyword(s):  
Heart Failure ◽  
Specific Pathogen Free ◽  
Free System ◽  
Specific Pathogen

scholarly journals The Blood Pressure, Life Span, Body Weight in Both Sexes of SHRSP during 55 Weeks under Specific Pathogen Free System

1979 ◽  
Vol 20 (5) ◽  
pp. 752-752
Author(s):  
Hideo Ueda ◽  
Naohiro Saito ◽  
Yoshio Suganuma ◽  
Hiroshi Matsuo
Keyword(s):  
Blood Pressure ◽  
Body Weight ◽  
Life Span ◽  
Specific Pathogen Free ◽  
Free System ◽  
Specific Pathogen

Laboratory Animal Research Centre (Larc) “A Specific Pathogen Free Rodent Facility” - Covid – 19 Pandemic Response Plan

2020 ◽  
Author(s):  
Muralitharan Shanmugakonar ◽  
Vijay Kanth Govindharajan ◽  
Kavitha Varadharajan ◽  
Hamda Al-Naemi
Keyword(s):  
Laboratory Animal ◽  
Animal Research ◽  
Research Centre ◽  
Functional Requirement ◽  
Specific Pathogen Free ◽  
Specific Pathogen ◽  
Response Plan ◽  
Pandemic Response ◽  
Operational Plan

Laboratory Animal Research Centre (LARC) has developed an early emergency operational plan for COVID-19 pandemic situation. Biosafety and biosecurity measures were planned and implemented ahead of time to check the functional requirement to prevent the infection. Identified necessary support for IT, transport, procurement, finance, admin and research to make the operations remotely and successfully.

Postmortem Specificity of Troponin for Acute Miocard Infarction Diagnosis throug Qualitative Dosing from Pericardial Fluid

2018 ◽  
Vol 69 (9) ◽  
pp. 2482-2486
Author(s):  
Iuliana Hunea ◽  
Simona Irina Damian ◽  
Carmen Corina Radu ◽  
Sorin Moldoveanu ◽  
Tatiana Iov
Keyword(s):  
Sudden Cardiac Death ◽  
Cardiac Disease ◽  
Cardiac Death ◽  
Troponin I ◽  
Troponin T ◽  
Morphological Changes ◽  
Pericardial Fluid ◽  
Histological Changes ◽  
Lethal Arrhythmia ◽  
Myocardial Lesions

Cardiac disease is the leading cause of death, and sudden cardiac death occupies the first place in sudden deaths of natural causes. Sudden cardiac death due to lethal arrhythmia may be the first manifestation of a cardiac disease, such cases becoming suspect dead, thus forensic cases. The autopsy performed in such cases may reveal important cardiovascular disease but not obvious macroscopic or histological changes of acute myocardial infarction (IMA), except for cases of survival for several hours after the onset of the symptomatology. Biochemical markers were used to test for myocardial lesions in the absence of morphological changes. Methods for determining myoglobin, CK-MB, troponin T (cTn T), troponin I (cTn I) were introduced to the clinic to diagnose the condition of patients with chest pain as early as the 1990s. The lack of pathognomonic elements in corps investigations, where part of the analysis cannot be carried out, requires verification of the value of the investigations that can be carried out, with reference to the biochemical in the present case, in establishing the diagnosis with certainty.

scholarly journals Curcumin reduces enteric isoprostane 8-iso-PGF2α and prostaglandin GF2α in specific pathogen-free Leghorn chickens challenged with Eimeria maxima

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Victor M. Petrone-Garcia ◽  
Raquel Lopez-Arellano ◽  
Gabriela Rodríguez Patiño ◽  
Miriam Aide Castillo Rodríguez ◽  
Daniel Hernandez-Patlan ◽  
...  
Keyword(s):  
Pilot Study ◽  
Broiler Chickens ◽  
Solid Phase ◽  
Oxidation Products ◽  
Specific Pathogen Free ◽  
Post Challenge ◽  
Eimeria Maxima ◽  
Lipid Oxidation Products ◽  
Challenge Control ◽  
Specific Pathogen

AbstractThe purpose of this pilot study was to evaluate and determine the concentration of prostaglandin GF2α (PGF2α) and isoprostane 8‐iso‐PGF2α in plasma and intestine of specific pathogen-free (SPF) Leghorn chickens challenged with Eimeria maxima, with or without dietary supplementation of curcumin using solid‐phase microextraction and ultra‐performance liquid chromatography/tandem mass spectrometry. Eighty 1-day-old male SPF chickens were randomly allocated to one of four groups with four replicates (n = 5 chickens/replicate). Groups consisted of: (1) Control (no challenge), (2) Curcumin (no challenge), (3) Eimeria maxima (challenge), and (4) Eimeria maxima (challenge) + curcumin. At day 28 of age, all chickens in the challenge groups were orally gavaged with 40,000 sporulated E. maxima oocysts. No significant differences (P > 0.05) were observed in the groups regardless of the treatment or challenge with E. maxima. Enteric levels of both isoprostane 8‐iso‐PGF2α and PGF2α at 7 days and 9 days post-challenge were significantly increased (P < 0.01) compared to the non-challenge control chickens. Interestingly, the enteric levels of both isoprostane 8‐iso‐PGF2α and PGF2α at 7 days post-challenge were significantly reduced in chickens fed curcumin, compared to control chickens challenge with E. maxima. At 9 days post-challenge, only levels of isoprostane 8‐iso‐PGF2α in the enteric samples were significantly reduced in chickens challenged with E. maxima supplemented with curcumin, compared with E. maxima challenge chickens. No differences of isoprostane 8‐iso‐PGF2α or PGF2α were observed in plasma at both days of evaluation. Similarly, no significant differences were observed between the challenge control or chickens challenge with E. maxima and supplemented with curcumin at both times of evaluation. The results of this pilot study suggests that the antioxidant anti-inflammatory properties of curcumin reduced the oxidative damage and subsequent intestinal mucosal over-production of lipid oxidation products. Further studies to confirm and extend these results in broiler chickens are required.

scholarly journals Attenuated fibrosis in specific pathogen‐free microbiota in experimental cholestasis‐ and toxin‐induced liver injury

2019 ◽  
Vol 33 (11) ◽  
pp. 12464-12476 ◽  
Author(s):  
Sheida Moghadamrad ◽  
Mohsin Hassan ◽  
Kathy D. McCoy ◽  
Jorum Kirundi ◽  
Philipp Kellmann ◽  
...  
Keyword(s):  
Liver Injury ◽  
Specific Pathogen Free ◽  
Specific Pathogen ◽  
Experimental Cholestasis

Effect of In Ovo Administered Reovirus Vaccines on Immune Responses of Specific-Pathogen-Free Chickens

10.1637/7087 ◽  
2004 ◽  
Vol 48 (1) ◽  
pp. 224-228 ◽  
Author(s):  
Z. Y. Guo ◽  
J. J. Giambrone ◽  
Z. Liu ◽  
T. V. Dormitorio ◽  
Hongzhuan Wu
Keyword(s):  
Immune Responses ◽  
Specific Pathogen Free ◽  
In Ovo ◽  
Specific Pathogen

scholarly journals Characteristic Intestinal Microflora of Specific Pathogen-Free Mice Bred in Two Different Colonies and their Influence on Postnatal Murine Immunocyte Profiles

2005 ◽  
Vol 54 (2) ◽  
pp. 143-148 ◽  
Author(s):  
Taizo NAGURA ◽  
Satoshi HACHIMURA ◽  
Shuichi KAMINOGAWA ◽  
Tsutomu ARITSUKA ◽  
Kikuji ITOH
Keyword(s):  
Intestinal Microflora ◽  
Specific Pathogen Free ◽  
Specific Pathogen
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