scholarly journals The Blood Pressure, Life Span, Body Weight in Both Sexes of SHRSP during 55 Weeks under Specific Pathogen Free System

1979 ◽  
Vol 20 (5) ◽  
pp. 752-752
Author(s):  
Hideo Ueda ◽  
Naohiro Saito ◽  
Yoshio Suganuma ◽  
Hiroshi Matsuo
Keyword(s):  
Blood Pressure ◽  
Body Weight ◽  
Life Span ◽  
Specific Pathogen Free ◽  
Free System ◽  
Specific Pathogen

scholarly journals Cardiac death and myocardial lesions in non-stroke SHRSP under specific pathogen-free system.

1981 ◽  
Vol 22 (3) ◽  
pp. 387-393 ◽  
Author(s):  
Hideo UEDA ◽  
Tadahiko MIYAZAKI ◽  
Yoshio SUGANUMA ◽  
Naohiro SAITO ◽  
Yasushi KATO
Keyword(s):  
Cardiac Death ◽  
Specific Pathogen Free ◽  
Free System ◽  
Specific Pathogen ◽  
Myocardial Lesions

Growth rate and growth composition of artificially reared piglets from specific pathogen free sows

1993 ◽  
Vol 56 (2) ◽  
pp. 217-223 ◽  
Author(s):  
M. W. A. Verstegen ◽  
W. van der Hel ◽  
F. J. M. Pijls
Keyword(s):  
Growth Rate ◽  
Body Weight ◽  
Nitrogen Balance ◽  
Environmental Temperature ◽  
Specific Pathogen Free ◽  
Protein Deposition ◽  
Daily Rate ◽  
Specific Pathogen ◽  
Balance Technique ◽  
The Mean

AbstractHeat production, energy and nitrogen balances of artificially reared piglets from specific pathogen free sows, housed in a respiratory chamber, were measured over five successive periods of 7 days each from 4 to 39 days of age. The experiment was carried out at an environmental temperature decreasing from 33 to 27°C. The mean weight increased from 1·5 (at day 4) to 11·9 kg (at day 39). Daily rate of gain increased from about 100 g in periods 1 and 2 to 502 g per piglet in the fifth period.Daily protein deposition, as measured via nitrogen balance, increased from 17 to 96 g; fat deposition increased from about 0 to 100 g. Body composition at the start and end was determined by a comparative slaughter technique. Protein and fat content had a high correlation coefficient with body weight (R2 = 0·69 and 0·89, respectively). At birth these values were much lower, 0·24 and 0·01 for protein and fat, respectively.Nitrogen balance compared with slaughter technique led to an overestimation for protein deposition of proportionately 0·07. Fat gain measured from slaughter was proportionately 0·08 lower than that calculated from energy balance.Ratio of gain estimated from protein and fat gain with the balance technique relative to that measured ranged between 0·93 to 1·15 in various periods.

scholarly journals LASTING BIOLOGICAL EFFECTS OF EARLY ENVIRONMENTAL INFLUENCES

1968 ◽  
Vol 127 (4) ◽  
pp. 783-799 ◽  
Author(s):  
René Dubos ◽  
Russell W. Schaedler ◽  
Richard Costello
Keyword(s):  
Life Span ◽  
Biological Effects ◽  
Foster Mother ◽  
Adult Size ◽  
Specific Pathogen Free ◽  
Depressing Effect ◽  
Average Life ◽  
Average Life Expectancy ◽  
Complete Diet ◽  
Specific Pathogen

Newborn specific-pathogen-free mice (SPF) were separated from their mothers shortly after birth and immediately reallocated at random to foster mothers, each of which received eight young. Under these conditions, the growth rate and adult size of the young were profoundly and lastingly conditioned by some unidentified influence exerted by the foster mother. In SPF mice nursed by their own mothers, the diet of the latter during gestation and lactation, or during lactation alone, conditioned the weight of the young at weaning time, and throughout their whole life span. Lasting depression of growth has been achieved by minor alterations of the dam's diet, for example by lowering its content in magnesium, or in lysine and threonine. The growth-depressing effect so achieved persisted throughout the whole life-span of the young, even though they were given at weaning time and constantly thereafter unlimited amounts of an optimum diet. In contrast, the weight-depressing effect of a diet deficient in lysine and threonine administered to adult animals was completely and rapidly reversible when a complete diet was later substituted for the deficient one. Depression of growth resulting from nutritional experiences during gestation or lactation did not seem to affect adversely the health of the young, or to decrease their longevity. In fact, the results of two experiments in which the animals nursed by mothers on different diets, were kept undisturbed and on optimum diets throughout their whole life span, suggest that the smaller animals had a greater average life expectancy than the larger ones.

scholarly journals Effect of Chronic Alcohol Consumption on Blood Pressure, Cerebral Stroke Lesions, Body Weight and Life-span in SHRSP

1995 ◽  
Vol 36 (4) ◽  
pp. 526-526
Author(s):  
Tetsuo Murakami ◽  
Hirotaka Kimura ◽  
Misa Yoshimura ◽  
Hajime Yoshizumi ◽  
Hiroshi Wada
Keyword(s):  
Blood Pressure ◽  
Body Weight ◽  
Alcohol Consumption ◽  
Life Span ◽  
Cerebral Stroke ◽  
Chronic Alcohol ◽  
Chronic Alcohol Consumption

scholarly journals The Heart Failure and Myocardial Changes of SHRSP derived from Non-stroke Parents under Specific Pathogen-free System

1980 ◽  
Vol 21 (4) ◽  
pp. 564-564 ◽  
Author(s):  
Hideo Ueda ◽  
Tadahiko Miyazaki ◽  
Atsushi Sakamoto ◽  
Kinya Hayakawa ◽  
Yoshio Suganuma ◽  
...  
Keyword(s):  
Heart Failure ◽  
Specific Pathogen Free ◽  
Free System ◽  
Specific Pathogen

scholarly journals Ultrastructural Changes of the Myocardium of SHRSP derived from the parents of Cardiac Death under Specific Pathogen-Free System

1981 ◽  
Vol 22 (3) ◽  
pp. 506-506
Author(s):  
Hideo Ueda ◽  
Tadahiko Miyazaki ◽  
Kinya Hayakawa ◽  
Yoshio Suganuma ◽  
Naohiro Saito ◽  
...  
Keyword(s):  
Cardiac Death ◽  
Ultrastructural Changes ◽  
Specific Pathogen Free ◽  
Free System ◽  
Specific Pathogen

Efficacy and safety of drospirenone-containing microdosage combined oral contraceptive use with starting contraception

GYNECOLOGY ◽  
2018 ◽  
Vol 20 (2) ◽  
pp. 9-13
Author(s):  
A R Khachaturian ◽  
E V Misharina ◽  
M I Yarmolinskaya
Keyword(s):  
Blood Pressure ◽  
Body Weight ◽  
Oral Contraceptive ◽  
Waist Circumference ◽  
Young Women ◽  
Iron Metabolism ◽  
Serum Iron ◽  
The Body ◽  
Menstrual Bleeding ◽  
Combined Oral Contraceptive

Androgen-dependent dermopathy, as well as premenstrual syndrome of varying severity in young women, can cause emotional depression, difficulties in social adaptation and even depressive disorders. The aim of the study was to study the safety and efficacy of using a combined oral contraceptive (COC) Dimia® containing 20 μg ethinyl estradiol and 3 mg drospirenone in young women, as well as its therapeutic effects in androgen-dependent dermopathy. Materials and methods. The study included 57 young women aged 23.1±2.2 years with signs of androgen-dependent dermopathy. The evaluation of the change in the character of menstrual bleeding, the anthropometric parameters (body weight, waist circumference and hips), the therapeutic effect of the drug on the symptoms of androgen-dependent dermopathy, as well as the dynamics of arterial pressure, hemoglobin level, serum iron have been studied. The psycho-emotional state was assessed using the SAN questionnaire (well-being-activity-mood). Results. During 6 months of observation, there was no significant change in the body mass index, waist circumference, and hips, and the drug did not affect the blood pressure numbers. Against the background of taking the drug, there was an increase in the parameters of iron metabolism (hemoglobin content, serum iron). After 3 months of taking the contraceptive with drospirenone, the number of patients with a complaint about the abundance of menstruation decreased more than twofold (from 22.8 to 10.5%), and after 6 months of taking the drug no patient noted the profuse nature of menstruation. Before the start of taking COC with drospirenone, 57.9% of women reported painful menstrual bleeding. Against the background of taking the contraceptive within 3 months, this complaint was stopped in all patients. Sufficient efficacy of treatment of androgen dependent dermopathy in young women with the help of a microdosed drospirenone-containing combined oral contraceptive is estimated from the dermatological acne index. The analysis of the SAN questionnaire made it possible to reveal the improvement in the psychoemotional state of patients on the background of taking the drug. The conclusion. The results obtained proved the effectiveness and safety of the microclinized COC Dimia®. The drug has no significant effect on body weight, blood pressure, provides reliable control of the cycle and a decrease in menstrual bleeding, which results in stabilization of iron metabolism in the body. Dimia® is effective in the treatment of androgen-dependent dermopathy and can be recommended to young women for starting contraception.

Laboratory Animal Research Centre (Larc) “A Specific Pathogen Free Rodent Facility” - Covid – 19 Pandemic Response Plan

2020 ◽  
Author(s):  
Muralitharan Shanmugakonar ◽  
Vijay Kanth Govindharajan ◽  
Kavitha Varadharajan ◽  
Hamda Al-Naemi
Keyword(s):  
Laboratory Animal ◽  
Animal Research ◽  
Research Centre ◽  
Functional Requirement ◽  
Specific Pathogen Free ◽  
Specific Pathogen ◽  
Response Plan ◽  
Pandemic Response ◽  
Operational Plan

Laboratory Animal Research Centre (LARC) has developed an early emergency operational plan for COVID-19 pandemic situation. Biosafety and biosecurity measures were planned and implemented ahead of time to check the functional requirement to prevent the infection. Identified necessary support for IT, transport, procurement, finance, admin and research to make the operations remotely and successfully.

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