scholarly journals Serum Uric Acid Is Associated With the Left Ventricular Mass Index in Males of a General Population

2014 ◽  
Vol 55 (1) ◽  
pp. 65-70 ◽  
Author(s):  
Ayako Yoshimura ◽  
Hisashi Adachi ◽  
Yuji Hirai ◽  
Mika Enomoto ◽  
Ako Fukami ◽  
...  
Keyword(s):  
Uric Acid ◽  
General Population ◽  
Left Ventricular Mass ◽  
Serum Uric Acid ◽  
Left Ventricular Mass Index ◽  
Left Ventricular ◽  
Ventricular Mass Index ◽  
Ventricular Mass

scholarly journals ARTERIAL HYPERTENSION ASSOCIATED WITH HYPERURICEMIA: FEATURES OF HEART DAMAGE

2020 ◽  
Vol 73 (5) ◽  
pp. 943-946
Author(s):  
Olha M. Chernatska ◽  
Liudmyla N. Prystupa ◽  
Hanna A. Fadieieva ◽  
Alina V. Liashenko ◽  
Yuliia O. Smiianova
Keyword(s):  
Uric Acid ◽  
Left Ventricular Hypertrophy ◽  
Arterial Hypertension ◽  
Left Ventricular Mass ◽  
Ventricular Hypertrophy ◽  
Left Ventricular Mass Index ◽  
Serum Uric Acid Level ◽  
Left Ventricular ◽  
Ventricular Mass Index ◽  
Ventricular Mass

The aim is the analysis of hyperuricemia influence on the heart features in patients with arterial hypertension. Materials and methods: We include 75 patients with arterial hypertension which were divided in two groups according to the level of uric acid in the blood, 30 practically healthy people. Patients from the I group (n = 40) had arterial hypertension and coexistent hyperuricemia; ІІ (n = 35) – arterial hypertension. Left ventricular mass index was determined for left ventricular hypertrophy confirmation. We used clinical, anthropometric, biochemical, instrumental, statistical method. Serum uric acid level was observed by the reaction with uricase. Left ventricular mass index was calculated as left ventricular mass to body surface area ratio. The results were analyzed statistically by SPSS 21 and Graphpad. Results: Left ventricular mass index was significantly higher (р = 0,0498) in patients from the І group (109,7 ± 3,21) g/m2 comparable with the ІІ (97,6 ± 5,35) g/m2 and increased in proportion to the biggest level of uric acid (r = 0,31; p = 0,04) in patients with arterial hypertension and hyperuricemia. Conclusions: Concentric and excentric left ventricular hypertrophy, increased left ventricular mass index proportionally to uric acid levels (r = 0,31; p = 0,04) is the confirmation of important role of hyperuricemia in the left ventricular hypertrophy development in patients with arterial hypertension.

scholarly journals Serum Uric Acid and Left Ventricular Mass in Essential Hypertension

2020 ◽  
Vol 7 ◽  
Author(s):  
Valeria Visco ◽  
Antonietta Valeria Pascale ◽  
Nicola Virtuoso ◽  
Felice Mongiello ◽  
Federico Cinque ◽  
...  
Keyword(s):  
Uric Acid ◽  
Left Ventricular Mass ◽  
Serum Uric Acid ◽  
Kidney Function ◽  
Left Ventricular Mass Index ◽  
Left Ventricular ◽  
University Hospital ◽  
Ventricular Mass ◽  
Severe Chronic Kidney Disease ◽  
Independent Association

Serum uric acid (sUA) has been associated with cardiovascular risk. Although the recent mechanistic hypothesis poses the basis for the association between sUA and left ventricular mass index (LVMi), the issue remains poorly investigated in a clinical setup. Through a retrospective analysis of the database of the departmental Hypertension Clinic of University Hospital of Salerno Medical School, we identified 177 essential hypertensives (age 60.3 ± 13.3 years; 85 men), free from uric acid-modulating medications and severe chronic kidney disease, and whose sUA values, anthropometric, clinical, and echocardiographic data were available. In the studied cohort, the average duration of hypertension was 8.4 ± 7.1 years. LVMi associated with classical determinants, such as age, blood pressure, and kidney function, although after multivariate correction, only age remained significant. Also, sUA correlated positively with LVMi, as well as body size, metabolism, and kidney function. In a multivariate analysis, sUA confirmed the independent association with LVMi. Also, levels of sUA >5.6 mg/dl are associated with larger cardiac size. We confirmed our data in a replicate analysis performed in a larger population (1,379 hypertensives) from an independent clinic. Our results demonstrate that sUA increases with LVMi, and a cutoff of 5.6 mg/dl predict larger LV sizes. Our data suggest that hyperuricemia might help to stratify the risk of larger cardiac size in hypertensives.

scholarly journals Is hepatic steatosis associated with left ventricular mass index increase in the general population?

2017 ◽  
Vol 9 (19) ◽  
pp. 857
Author(s):  
Katharina Piontek ◽  
Carsten O Schmidt ◽  
Sebastian E Baumeister ◽  
Markus M Lerch ◽  
Julia Mayerle ◽  
...  
Keyword(s):  
General Population ◽  
Hepatic Steatosis ◽  
Left Ventricular Mass ◽  
Left Ventricular Mass Index ◽  
Left Ventricular ◽  
Ventricular Mass Index ◽  
Ventricular Mass

scholarly journals Uric Acid, Left Ventricular Mass Index, and Risk of Cardiovascular Disease in Essential Hypertension

Hypertension ◽  
2006 ◽  
Vol 47 (2) ◽  
pp. 195-202 ◽  
Author(s):  
Yoshio Iwashima ◽  
Takeshi Horio ◽  
Kei Kamide ◽  
Hiromi Rakugi ◽  
Toshio Ogihara ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Uric Acid ◽  
Essential Hypertension ◽  
Left Ventricular Mass ◽  
Left Ventricular Mass Index ◽  
Left Ventricular ◽  
Ventricular Mass Index ◽  
Ventricular Mass
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