Fluoride modulates formation and function of bone marrow macrophage-derived osteoclasts in a strain-specific manner

2016 ◽  
Author(s):  
Oliveira Flavia Amadeu de ◽  
Pereira Amanda Amaral ◽  
Silva Ventura Talita da ◽  
Buzalaf Marilia Afonso Rabelo ◽  
Oliveira Rodrigo Cardoso de ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Macrophage ◽  
Specific Manner ◽  
And Function

scholarly journals Activin A inhibits RANKL-mediated osteoclast formation, movement and function in murine bone marrow macrophage cultures

2015 ◽  
Vol 128 (4) ◽  
pp. 683-694 ◽  
Author(s):  
T. W. Fowler ◽  
A. Kamalakar ◽  
N. S. Akel ◽  
R. C. Kurten ◽  
L. J. Suva ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Activin A ◽  
Osteoclast Formation ◽  
Bone Marrow Macrophage ◽  
Murine Bone Marrow ◽  
And Function

Maternal High-Fat Diet Persistently Alters Bone Marrow Immune Cell Proportions and Function in a Nonhuman Primate Model

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 222-OR
Author(s):  
MICHAEL J. NASH ◽  
TAYLOR K. SODERBORG ◽  
RACHEL C. JANSSEN ◽  
ERIC M. PIETRAS ◽  
JACOB E. FRIEDMAN
Keyword(s):  
Bone Marrow ◽  
Nonhuman Primate ◽  
High Fat Diet ◽  
Immune Cell ◽  
High Fat ◽  
Nonhuman Primate Model ◽  
Primate Model ◽  
And Function

scholarly journals Murine Bone Marrow Stromally Derived BMS2 Adipocytes Support Differentiation and Function of Osteoclast-Like Cellsin Vitro1

Endocrinology ◽  
1998 ◽  
Vol 139 (4) ◽  
pp. 2092-2101 ◽  
Author(s):  
Katherine A. Kelly ◽  
Sakae Tanaka ◽  
Roland Baron ◽  
Jeffrey M. Gimble
Keyword(s):  
Bone Marrow ◽  
Murine Bone Marrow ◽  
And Function

Functional absence of neutral endopeptidase in mice promotes hapten uptake, maturation and function of bone marrow-derived dendritic cells

2008 ◽  
Vol 13 (9) ◽  
pp. 587-587
Author(s):  
T. E. Scholzen ◽  
M. Fastrich ◽  
T. Brzoska ◽  
C. A. Armstrong ◽  
J. C. Ansel ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Dendritic Cells ◽  
Neutral Endopeptidase ◽  
And Function

Biology of bone marrow-derived endothelial cell precursors

2007 ◽  
Vol 292 (1) ◽  
pp. H1-H18 ◽  
Author(s):  
Gina C. Schatteman ◽  
Martine Dunnwald ◽  
Chunhua Jiao
Keyword(s):  
Bone Marrow ◽  
Endothelial Cell ◽  
Marrow Cell ◽  
Tumor Type ◽  
Physiological Relevance ◽  
Bone Marrow Derived Cells ◽  
And Function ◽  
Endothelial Nitric Oxide ◽  
The Impact ◽  
Endothelial Precursors

Over the past decade, the old idea that the bone marrow contains endothelial cell precursors has become an area of renewed interest. While some still believe that there are no endothelial precursors in the blood, even among those who do, there is no consensus as to what they are or what they do. In this review, we describe the problems in identifying endothelial cells and conclude that expression of endothelial nitric oxide synthase may be the most reliable antigenic indicator of the phenotype. The evidence for two different classes of endothelial precursors is also presented. We suggest that, though there is no single endothelial cell precursor, we may be able to use these phenotypic variations to our advantage in better understanding their biology. We also discuss how a variety of genetic, epigenetic, and methodological differences can account for the seemingly contradictory findings on the physiological relevance of bone marrow-derived precursors in normal vascular maintenance and in response to injury. Data on the impact of tumor type and location on the contribution of bone marrow-derived cells to the tumor vasculature are also presented. These data provide hope that we may ultimately be able to predict those tumors in which bone marrow-derived cells will have a significant contribution and design therapies accordingly. Finally, factors that regulate bone marrow cell recruitment to and function in the endothelium are beginning to be identified, and several of these, including stromal derived factor 1, monocyte chemoattractant factor-1, and vascular endothelial growth factor are discussed.

scholarly journals Myelin Debris Stimulates NG2/CSPG4 Expression in Bone Marrow-Derived Macrophages in the Injured Spinal Cord

2021 ◽  
Vol 15 ◽  
Author(s):  
Yang Liu ◽  
Grace Hammel ◽  
Minjun Shi ◽  
Zhijian Cheng ◽  
Sandra Zivkovic ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Bone Marrow ◽  
Spinal Cord Injury ◽  
Phagocytic Capacity ◽  
Myelin Sheaths ◽  
Cellular Debris ◽  
Cord Injury ◽  
And Function ◽  
Secondary Spinal Cord Injury ◽  
First Time

Although the increased expression of members of the chondroitin sulfate proteoglycan family, such as neuron-glial antigen 2 (NG2), have been well documented after an injury to the spinal cord, a complete picture as to the cellular origins and function of this NG2 expression has yet to be made. Using a spinal cord injury (SCI) mouse model, we describe that some infiltrated bone marrow-derived macrophages (BMDMΦ) are early contributors to NG2/CSPG4 expression and secretion after SCI. We demonstrate for the first time that a lesion-related form of cellular debris generated from damaged myelin sheaths can increase NG2/CSPG4 expression in BMDMΦ, which then exhibit enhanced proliferation and decreased phagocytic capacity. These results suggest that BMDMΦ may play a much more nuanced role in secondary spinal cord injury than previously thought, including acting as early contributors to the NG2 component of the glial scar.

Dynamics of adrenal morphology and function in irradiated recipients after bone marrow transplantation

1989 ◽  
Vol 107 (6) ◽  
pp. 882-884
Author(s):  
A. A. Tsutsaeva ◽  
T. A. Glushko ◽  
L. E. Shatilova ◽  
N. G. Golubeva
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Transplantation ◽  
Marrow Transplantation ◽  
And Function
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