Abnormal trabecular micro-architecture and bone mechanical properties in adolescent idiopathic scoliosis: a case-control study with high-resolution peripheral quantitative computed tomography and finite element analysis

2015 ◽  
Author(s):  
Ka Yee Cheuk ◽  
Huanxiong Chen ◽  
Fiona Yu ◽  
Tsz Ping Lam ◽  
Simon K M Lee ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Mechanical Properties ◽  
Finite Element Analysis ◽  
Finite Element ◽  
Case Control Study ◽  
Quantitative Computed Tomography ◽  
Peripheral Quantitative Computed Tomography ◽  
Case Control ◽  
Element Analysis ◽  
Control Study

scholarly journals Effects of Scan Resolutions and Element Sizes on Bovine Vertebral Mechanical Parameters from Quantitative Computed Tomography-Based Finite Element Analysis

2017 ◽  
Vol 2017 ◽  
pp. 1-14 ◽  
Author(s):  
Meng Zhang ◽  
Jiazi Gao ◽  
Xu Huang ◽  
He Gong ◽  
Min Zhang ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Finite Element Analysis ◽  
Finite Element ◽  
Quantitative Computed Tomography ◽  
Slice Thickness ◽  
Mechanical Parameters ◽  
Ct Scanner ◽  
Computational Accuracy ◽  
Element Analysis ◽  
Vertebral Strength

Quantitative computed tomography-based finite element analysis (QCT/FEA) has been developed to predict vertebral strength. However, QCT/FEA models may be different with scan resolutions and element sizes. The aim of this study was to explore the effects of scan resolutions and element sizes on QCT/FEA outcomes. Nine bovine vertebral bodies were scanned using the clinical CT scanner and reconstructed from datasets with the two-slice thickness, that is, 0.6 mm (PA resolution) and 1 mm (PB resolution). There were significantly linear correlations between the predicted and measured principal strains (R2>0.7, P<0.0001), and the predicted vertebral strength and stiffness were modestly correlated with the experimental values (R2>0.6, P<0.05). Two different resolutions and six different element sizes were combined in pairs, and finite element (FE) models of bovine vertebral cancellous bones in the 12 cases were obtained. It showed that the mechanical parameters of FE models with the PB resolution were similar to those with the PA resolution. The computational accuracy of FE models with the element sizes of 0.41 × 0.41 × 0.6 mm3 and 0.41 × 0.41 × 1 mm3 was higher by comparing the apparent elastic modulus and yield strength. Therefore, scan resolution and element size should be chosen optimally to improve the accuracy of QCT/FEA.

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