Influence of estrogen administration on growth hormone stimulation in patients with Turner's syndrome

1987 ◽  
Vol 116 (3_Suppl) ◽  
pp. S175-S176 ◽  
Author(s):  
E. SCHOBER ◽  
H. FRISCH ◽  
F. WALDHAUSER ◽  
CH. BIEGELMAYER
Keyword(s):  
Growth Hormone ◽  
Turner's Syndrome ◽  
Turner’S Syndrome ◽  
Hormone Stimulation ◽  
Estrogen Administration

Influence of estrogen administration on growth hormone response to GHRH and L-Dopa in patients with Turner's syndrome

1989 ◽  
Vol 120 (4) ◽  
pp. 442-446 ◽  
Author(s):  
E. Schober ◽  
H Frisch ◽  
F. Waldhauser ◽  
Ch. Bieglmayr
Keyword(s):  
Growth Hormone ◽  
Priming Effect ◽  
Ovarian Failure ◽  
Estrogen Deficiency ◽  
Growth Hormone Response ◽  
Turner's Syndrome ◽  
Hormone Response ◽  
Turner’S Syndrome ◽  
Gh Secretion ◽  
Estrogen Administration

Abstract. The modulating effect of estrogen on GH secretion was studied in 22 patients with Turner's syndrome. Estrogen administration (0.5 μg/kg ethinylestradiol) for a period of 4 weeks resulted in a significant increase in basal GH concentrations (2.6 vs 4.8 μg/l, P< 0.01). The L-Dopa-stimulated GH concentrations were also significantly increased (P< 0.01), whereas no effect of estrogen substitution on GH responses to GHRH (1–44) and Sm-C levels was seen. Our findings demonstrate a priming effect of estrogen on GH secretion in patients with Turner's syndrome. These patients generally lack the puberty-associated rise in GH secretion, which might be due to ovarian failure and the concomitant estrogen deficiency.

Growth Hormone Stimulation in Patients with Turner's Syndrome: Influence of Oestrogen Administration

2008 ◽  
Vol 77 ◽  
pp. 178-179
Author(s):  
H. FRISCH ◽  
E. SCHOBER ◽  
F. WALDHAUSER ◽  
C. BIEGELMAYER
Keyword(s):  
Growth Hormone ◽  
Turner's Syndrome ◽  
Turner’S Syndrome ◽  
Hormone Stimulation

scholarly journals Growth Hormone plus Childhood Low-Dose Estrogen in Turner's Syndrome

2011 ◽  
Vol 364 (13) ◽  
pp. 1230-1242 ◽  
Author(s):  
Judith L. Ross ◽  
Charmian A. Quigley ◽  
Dachuang Cao ◽  
Penelope Feuillan ◽  
Karen Kowal ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Low Dose ◽  
Turner's Syndrome ◽  
Turner’S Syndrome

scholarly journals Effect of obesity on endogenous secretion of growth hormone in Turner's syndrome.

1991 ◽  
Vol 66 (10) ◽  
pp. 1184-1190 ◽  
Author(s):  
P W Lu ◽  
C T Cowell ◽  
M Jimenez ◽  
J M Simpson ◽  
M Silink
Keyword(s):  
Growth Hormone ◽  
Turner's Syndrome ◽  
Turner’S Syndrome

scholarly journals Growth hormone secretion in subjects with ovarian dysgenesis and Turner's syndrome.

1968 ◽  
Vol 43 (231) ◽  
pp. 595-597 ◽  
Author(s):  
S. R. Meadow ◽  
B. J. Boucher ◽  
K. Mashiter ◽  
M. N. King ◽  
L. Stimmler
Keyword(s):  
Growth Hormone ◽  
Hormone Secretion ◽  
Growth Hormone Secretion ◽  
Turner's Syndrome ◽  
Turner’S Syndrome ◽  
Ovarian Dysgenesis

Growth-Stimulating Effects of Human Growth Hormone Therapy in Turner’s Syndrome

1986 ◽  
pp. 109-113 ◽  
Author(s):  
Salvatore Raiti ◽  
S. L. Kaplan ◽  
G. P. August ◽  
S. A. Kaplan ◽  
M. H. MacGillivray ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Hormone Therapy ◽  
Human Growth Hormone ◽  
Growth Hormone Therapy ◽  
Human Growth ◽  
Turner's Syndrome ◽  
Turner’S Syndrome

Growth Hormone and Craniofacial Changes: Preliminary Data From Studies in Turner's Syndrome

PEDIATRICS ◽  
1999 ◽  
Vol 104 (Supplement_5) ◽  
pp. 1021-1024
Author(s):  
Kirt E. Simmons
Keyword(s):  
Growth Hormone ◽  
Growth Factor ◽  
Dental Development ◽  
Turner's Syndrome ◽  
Craniofacial Growth ◽  
Insulin Like Growth Factor ◽  
Turner’S Syndrome ◽  
Mandibular Growth ◽  
Factor I ◽  
Control Subjects

Normal craniofacial and dental growth and development is dependent on growth hormone (GH) and insulin-like growth factor I (IGF-I). Deficiencies of either during childhood cause diminished growth of the maxilla and (to a greater degree) the mandible. Dental development/eruption also is compromised. Conversely, excessive GH/insulin-like growth factor I causes overgrowth, with the mandible again more affected than the maxilla. Replacement therapy in deficiency conditions generally normalizes craniofacial growth. Systemic GH also has been used in other disorders for which overt deficiency of GH has not been demonstrated. One such condition, Turner's syndrome, is now widely treated with GH. Although systemic GH in Turner's syndrome has been shown to positively affect stature, the effects on craniofacial growth and dental development/eruption are largely unknown. To explore these issues, standardized lateral radiographs of seven untreated patients with Turner's syndrome were analyzed and revealed hypoplasias of the cranial base, maxilla, and mandible. Dental development/eruption of patients with Turner's syndrome was found to be significantly advanced (by 0.63 years), relative to control subjects, in a separate study. Annual radiocephalometric measurements of 19 patients with Turner's syndrome treated with GH were compared with nonaffected control subjects over 1 year of treatment. Compared with age-matched historic control subjects, all maxillary—and most mandibular—growth measures were within 2 standard deviations of control. However, in our patients with Turner's syndrome, we found two measures of mandibular growth that deviated by more than 3 standard deviations from control. These data, although preliminary and only encompassing a short period, indicate that mandibular growth may be more affected than is maxillary growth by GH treatment and should be monitored over long-term-therapy.

Turner’s Syndrome and Human Growth Hormone

1986 ◽  
pp. 115-121 ◽  
Author(s):  
G. Van Vliet ◽  
D. M. Styne ◽  
S. L. Kaplan ◽  
M. M. Grumbach
Keyword(s):  
Growth Hormone ◽  
Human Growth Hormone ◽  
Human Growth ◽  
Turner's Syndrome ◽  
Turner’S Syndrome

scholarly journals Near Normalization of Final Height with Adapted Doses of Growth Hormone in Turner’s Syndrome

1998 ◽  
Vol 83 (5) ◽  
pp. 1462-1466 ◽  
Author(s):  
Jean-Claude Carel ◽  
Laurence Mathivon ◽  
Christine Gendrel ◽  
Jean-Pascal Ducret ◽  
Jean-Louis Chaussain
Keyword(s):  
Growth Hormone ◽  
Final Height ◽  
Turner's Syndrome ◽  
Turner’S Syndrome
Sign in / Sign up

Export Citation Format

Share Document