Influence of low-dose etomidate on adrenal and gonadal steroid hormone secretion in normal men

1986 ◽  
Vol 113 (1_Suppl) ◽  
pp. S21-S22 ◽  
Author(s):  
D. ENGELHARDT ◽  
H. SUTTMANN ◽  
K. JACOB ◽  
H.G. DÖRR
Keyword(s):  
Low Dose ◽  
Steroid Hormone ◽  
Hormone Secretion ◽  
Gonadal Steroid ◽  
Normal Men

Gonadal steroid hormone secretion during the juvenile period depends on host-specific microbiota and contributes to the development of odor preference

2019 ◽  
Vol 61 (5) ◽  
pp. 670-678 ◽  
Author(s):  
Itsuka Kamimura ◽  
Akiyuki Watarai ◽  
Takuma Takamura ◽  
Atsushi Takeo ◽  
Kyoko Miura ◽  
...  
Keyword(s):  
Steroid Hormone ◽  
Hormone Secretion ◽  
Gonadal Steroid ◽  
Juvenile Period ◽  
Odor Preference

Low-Dose Brain Natriuretic Peptide Infusion in Normal Men and the Influence of Endopeptidase Inhibition

1997 ◽  
Vol 92 (3) ◽  
pp. 255-260 ◽  
Author(s):  
C. M. Florkowski ◽  
A. M. Richards ◽  
E. A. Espiner ◽  
T. G. Yandle ◽  
E. Sybertz ◽  
...  
Keyword(s):  
Atrial Natriuretic Peptide ◽  
Plasma Renin Activity ◽  
Brain Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Low Dose ◽  
Plasma Renin ◽  
Renin Activity ◽  
Plasma Brain Natriuretic Peptide ◽  
Normal Men ◽  
Atrial Natriuretic

1. To assess the threshold dose for bioactivity of brain natriuretic peptide and the role of endopeptidase 24.11 in metabolism of brain natriuretic peptide at physiological plasma levels, we studied eight normal men receiving 2 h infusions of low-dose brain natriuretic peptide [0.25 and 0.5 pmol min−1 kg−1 with and without pretreatment with an endopeptidase inhibitor (SCH 32615, 250 mg intravenously)] in placebo-controlled studies. 2. Plasma brain natriuretic peptide increased 2-fold during the infusion of 0.25 pmol min−1 kg−1 (mean increment above control 3.9 pmol/l, P < 0.001), and tripled (P < 0.001) with 0.5 pmol min−1 kg−1. Plasma renin activity was inhibited by both doses (14.8%, P < 0.01, and 20%, P < 0.001, respectively). A significant natriuresis (56% increase in urine sodium/creatinine ratio, P < 0.02) occurred with the higher dose. Blood pressure, haematocrit, plasma cGMP, atrial natriuretic peptide and aldosterone were unaffected by either dose. 3. Compared with brain natriuretic peptide (0.5 pmol min−1 kg−1) alone, SCH 32615 pretreatment increased peak plasma brain natriuretic peptide (13.4±0.78 versus 12.4±0.86 pmol/l, P < 0.05), ANP (7.5±0.96 versus 5.9±0.4 pmol/l, P < 0.01) and cGMP (4.8 ± 1.7 versus 3.9 ± 1.4 nmol/l, P < 0.001). Plasma renin activity was further suppressed with SCH 32615 pretreatment (29% compared with 20%, P < 0.001). 4. Small acute increments in plasma brain natriuretic peptide (4 pmol/l) have significant biological effects in normal men without altering plasma atrial natriuretic peptide or cGMP.

scholarly journals Effects of Azomite enriched diet on gonadal steroid hormone levels and milt quality indices in Oreochromis mossambicus

2020 ◽  
Vol 17 ◽  
pp. 100341 ◽  
Author(s):  
Habeeb Ashik Ahamed ◽  
Mohamed Jamal Mohamed ◽  
Kantha Deivi Arunachalam ◽  
G.I. Darul Raiyaan ◽  
Mohamed Saiyad Musthafa ◽  
...  
Keyword(s):  
Steroid Hormone ◽  
Oreochromis Mossambicus ◽  
Gonadal Steroid ◽  
Quality Indices ◽  
Hormone Levels

Sleep deprivation reduces LH secretion in men independently of melatonin

1991 ◽  
Vol 124 (6) ◽  
pp. 646-651 ◽  
Author(s):  
RickJ. Strassman ◽  
Clifford R. Qualls ◽  
E.Jonathan Lisansky ◽  
Glenn T. Peake
Keyword(s):  
Sleep Deprivation ◽  
Hormone Secretion ◽  
Area Under The Curve ◽  
Bright Light ◽  
Pulse Frequency ◽  
Blood Levels ◽  
Luteinizing Hormone Secretion ◽  
Normal Man ◽  
Normal Men ◽  
Lh Secretion

Abstract. Melatonin affects gonadal function in nonprimate mammals. Confirmatory data in man are not available. We assessed melatonin's acute effects on luteinizing hormone secretion in 17 normal men. We studied these men in conditions of sleep in the dark, and sleep deprivation in bright light, dim light, and bright light combined with a physiologically relevant infusion of melatonin, while measuring blood levels of immunoreactive LH every 20 min for 7 h. We compared overnight LH secretion, and LH pulse frequency, amplitude, length, interval and area under the curve using a modification of the PULSAR peak identification program, among the four treatments. Areas under the curve for peaks in all three conditions of sleep deprivation were lower than in normal sleep. The presence or absence of melatonin had no additional effect. We conclude that acute suppression of melatonin does not affect LH pulse parameters in normal man, but that sleep deprivation may reduce the amount of LH secreted per pulse.

Twenty-Four Hour Pattern of Luteinizing Hormone Secretion in Normal Men with Sleep Stage Recording

1972 ◽  
Vol 35 (1) ◽  
pp. 73-81 ◽  
Author(s):  
ROBERT BOYAR ◽  
MARK PERLOW ◽  
LEON HELLMAN ◽  
SHELDON KAPEN ◽  
ELLIOT WEITZMAN
Keyword(s):  
Luteinizing Hormone ◽  
Sleep Stage ◽  
Hormone Secretion ◽  
Luteinizing Hormone Secretion ◽  
Normal Men
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