PERSISTING HIGH LEVEL OF TRANSMITTER IN UTERINE SHORT ADRENERGIC NEURONS FOLLOWING PROLONGED TREATMENT WITH 17β-OESTRADIOL

1969 ◽  
Vol 62 (1) ◽  
pp. 77-81 ◽  
Author(s):  
B. Falck ◽  
Ch. Owman ◽  
E. Rosengren ◽  
N.-O. Sjöberg
Keyword(s):  
Experimental Period ◽  
Sympathetic Chain ◽  
Prolonged Treatment ◽  
Adrenergic Nerve ◽  
Nerve Supply ◽  
Noradrenaline Content ◽  
Adrenergic Neurons ◽  
Short Adrenergic Neurons ◽  
High Level

ABSTRACT The myometrium of the rabbit uterus receives its adrenergic nerve supply by way of short adrenergic neurons originating in peripheral ganglia located at the uterovaginal junction. Treatment with 17β-oestradiol daily for 4 weeks produced a doubling of the total noradrenaline content of the uterus, as measured fluorimetrically. This high transmitter level persisted even if the oestrogen administration was interrupted after half the experimental period. No changes occurred in the noradrenaline content of the control organs (heart and ovary) which are innervated by ordinary long adrenergic neurons from the sympathetic chain. The significance of the present results for the marked changes in uterine noradrenaline previously found during pregnancy is discussed.

EFFECT OF HIGH DOSES OF OESTROGEN AND PROGESTERONE ON THE NORADRENALINE CONTENT OF THE SHORT ADRENERGIC NEURONS INNERVATING THE MALE GENITAL TRACT OF THE RAT

1970 ◽  
Vol 64 (3) ◽  
pp. 459-465 ◽  
Author(s):  
Ch. Owman ◽  
N.-O. Sjöberg ◽  
N. O. Sjöstrand ◽  
G. Swedin
Keyword(s):  
Genital Tract ◽  
Reproductive Tract ◽  
Female Genital Tract ◽  
Total Content ◽  
Prolonged Treatment ◽  
Noradrenaline Content ◽  
Adrenergic Neurons ◽  
Short Adrenergic Neurons ◽  
High Doses ◽  
Male Genital

ABSTRACT The effect of prolonged treatment with high doses of oestrogen and/or progesterone on the amount of adrenergic transmitter in the short adrenergic neurons of the male reproductive tract of castrated rats has been studied by chemical determinations and histochemical demonstration of noradrenaline. Oestrogen, progesterone, or a combination of both, had no overt effect on the total content or on the concentration of noradrenaline in the male genital organs. The results are discussed in the light of recent findings that the content of the noradrenaline transmitter in the short adrenergic neurons to the female genital tract is markedly influenced by these female sex hormones.

scholarly journals Quality of colostral passive immunity and pattern of serum protein fluctuation in newborn calves

2003 ◽  
Vol 60 (3) ◽  
pp. 453-456 ◽  
Author(s):  
Patricia Pauletti ◽  
Raul Machado Neto ◽  
Irineu Umberto Packer ◽  
Raul Dantas D'Arce ◽  
Rosana Bessi
Keyword(s):  
Total Protein ◽  
Statistical Design ◽  
Extended Period ◽  
Experimental Period ◽  
Passive Immunity ◽  
Serum Total Protein ◽  
Non Linear ◽  
Medium Level ◽  
Group 2 ◽  
High Level

Immunity acquired by newborn animals is known as passive immunity, and for ruminants, antibody acquisition depends on the ingestion and absorption of adequate amounts of immunoglobulins from colostrum. This study relates different initial levels of acquired passive protection and serum total protein (TP) and immunoglobulin G (IgG). Serum immunoglobulin concentration and total protein were evaluated for female Holstein calves in the first sixty days of life. Animals were separated into three groups according to their initial level of passive immunity: group 1- animals with a low level of passive immunity (below 20 mg mL-1); group 2- animals with a medium level (between 20 and 30 mg mL-1), and group 3- animals with a high level (above 30 mg mL-1). Serum total protein was determined through the biuret method and IgG was determined by radial immunodiffusion. Data were analyzed as a completely randomized, split-plot statistical design. Fluctuation of the variables along the experimental period was determined through non-linear regression by the DUD method (PROC NLIN - Non Linear SAS). Animals with low antibody acquisition started to produce antibodies earlier, reflecting a compensatory synthesis. On the other hand, animals having adequate levels exhibited an extended period of immunoglobulin catabolism and the beginning of the endogenous phase was delayed. Regardless initial levels, the fluctuations in IgG contents occurred around adequate physiological concentrations, ranging from 20 to 25 mg mL-1.

Clarification: netilmicin in endocarditis (6 March, p19)

1989 ◽  
Vol 27 (10) ◽  
pp. 40-40
Keyword(s):  
Laboratory Tests ◽  
Optimal Treatment ◽  
Prolonged Treatment ◽  
Gentamicin Resistance ◽  
High Level ◽  
Faecal Streptococci

We suggested that netilmicin might be preferable to gentamicin in endocarditis caused by faecal streptococci to reduce unwanted effects from prolonged treatment. “Faecal streptococci” comprise two species, Strep faecalis, and the rare Strep faecium which is innately resistant to netilmicin as we noted in 1982. Both species are increasingly showing high-level gentamicin resistance in America. Laboratory tests are essential to determine optimal treatment, and netilmicin should not be universally substituted for gentamicin in endocarditis caused by unspeciated “faecal streptococci”.

Benign thyroid swelling presenting as Horner’s syndrome

2020 ◽  
Vol 13 (12) ◽  
pp. e235313
Author(s):  
Sherin K Shaji ◽  
Jacquline Chan ◽  
Churunal Hari
Keyword(s):  
Pressure Effect ◽  
Sympathetic Chain ◽  
Horner’S Syndrome ◽  
Nerve Supply ◽  
Common Condition ◽  
Horner's Syndrome ◽  
First Case ◽  
Cervical Sympathetic ◽  
Thyroid Swelling ◽  
Benign Thyroid

Horner’s syndrome is a rare neurological condition seen in association with the disruption in the sympathetic nerve supply. Thyroid swelling is a common condition but rarely causes cervical sympathetic chain compression. We describe a case of a 54-year-old man who presented with Horner’s syndrome secondary to a benign thyroid nodule with pressure effect on the sympathetic chain. An association between thyroid pathologies and Horner’s syndrome has been mentioned previously, however, to our knowledge, this is the first case of Horner’s syndrome being the initial presentation for an underlying benign thyroid swelling.

Some nutritional implications of group-feeding hill sheep

1973 ◽  
Vol 16 (3) ◽  
pp. 293-302 ◽  
Author(s):  
Janet Z. Foot ◽  
A. J. F. Russel
Keyword(s):  
Fatty Acid ◽  
Dry Matter ◽  
Experimental Period ◽  
The Other ◽  
Daily Group ◽  
Group Feeding ◽  
Principal Factors ◽  
Group A ◽  
Group B ◽  
High Level

SUMMARYIn the first experiment two groups of 11 Scottish Blackface ewes were given either 6·10 kg dried grass pellets plus 1·63 kg chopped dried grass daily (Group A) or 8·17 kg hay plus 1·32 kg oat pellets (Group B). During a 10-day experimental period individual dry-matter intakes ranged from 484 to 939 g/day (CV 22·3%) in Group A and from 613 to 883 g/day (CV 13·3%) in Group B. In Group B dry-matter intakes from oats were much more variable (10 to 149 g/day; CV 35·8%) than those from hay (530 to 762 g/day; CV 12·9%). Plasma protein-bound iodine (PBI) concentrations were significantly higher in the Group A sheep.In the second experiment the treatments were: group-penned, group-fed (GG); group-penned, individually fed (GI); and individually penned, individually fed (II). Within each treatment there were two groups of 12 ewes; one group was given a high level of feeding (H) and the other a low level (L) for a 7-week experimental period. Allowances of pelleted concentrates ranged from 7 to 15 g/kg in the L groups and from 18 to 26 g/kg in the H groups. The same mean quantities per kg were given to GG sheep, and food intakes ranged from 5·7 to 17·7 g/kg (CV 25·3%) in GGL and from 12·5 to 30·8 g/kg (CV 24·8%) in GGH. Plasma PBI concentrations were significantly higher in L sheep than in H sheep, and higher in GG than in II. Plasma non-esterified fatty acid concentrations were significantly higher in L sheep than in H sheep and higher in GG than in GI and II.The principal factors determining variations in food intakes between individual animals fed in groups and some of the nutritional implications of group-feeding sheep are discussed.

Supersensitivity of the Isolated Rat Heart after Chemical Sympathectomy with 6-Hydroxydopamine

1971 ◽  
Vol 49 (1) ◽  
pp. 36-44 ◽  
Author(s):  
R. A. Nadeau ◽  
J. De Champlain ◽  
G. M. Tremblay
Keyword(s):  
Nerve Fibers ◽  
Isolated Rat Heart ◽  
Adrenergic Nerve ◽  
Noradrenaline Content ◽  
Chronotropic Response ◽  
Endogenous Noradrenaline ◽  
6 Hydroxydopamine ◽  
Perfused Hearts ◽  
Supersensitivity To Noradrenaline ◽  
Isolated Rat

Presynaptic supersensitivity was demonstrated in isolated rat atria and perfused hearts 2 h after an intravenous injection of 6-hydroxydopamine (6-OH-DA), 100 mg/kg. This coincided with a maximum depletion of cardiac endogenous noradrenaline, a disappearance of the fluorescence of terminal adrenergic nerve fibers in the atrial myocardium, and an abolished chronotropic response to tyramine. The chronotropic response to dopamine was also significantly diminished. Maximal supersensitivity to the chronotropic effect of noradrenaline was observed 72 h after the injection of 6-OH-DA. Two weeks after the administration of 6-OH-DA, supersensitivity to noradrenaline was less marked, and the response to tyramine was restored. These changes corresponded to an increasing noradrenaline content in the heart and to the reappearance of histofluorescent fibers in the atria.

Blockade of the Antiadrenergic Action of Bretylium by an Aqueous Extract of the Leaves of Rhoeo spathacea

1971 ◽  
Vol 49 (12) ◽  
pp. 1106-1110 ◽  
Author(s):  
M. Garcia ◽  
C. Miyares ◽  
E. Menendez ◽  
F. Sainz
Keyword(s):  
Aqueous Extract ◽  
Inhibitory Response ◽  
Adrenergic Nerve ◽  
Nerve Supply ◽  
Rabbit Ileum ◽  
Dopamine Content ◽  
Stimulation Of

In isolated rabbit ileum, bretylium-induced blockade of the inhibitory response to stimulation of the adrenergic nerve supply is prevented by an aqueous extract of the leaves of Rhoeo spathacea, apparently as a result of its dopamine content.

High Level Cereal Diets for the Growing/Finishing Pig: VII. The Performance Of Weaned Pigs Grown To Cutter Weight (160 lb live weight) on Iso-Nitrogenous-Maize Based Diets Containing Different Levels of Lysine and Tryptophan

1972 ◽  
Vol 79 (1) ◽  
pp. 161-164 ◽  
Author(s):  
T. L. J. Lawrence
Keyword(s):  
Live Weight ◽  
Experimental Period ◽  
Superior Performance ◽  
Large White ◽  
Finishing Pig ◽  
White Type ◽  
Dry Food ◽  
High Level ◽  
Weaner Pigs ◽  
Different Levels

SUMMARYIn a randomized block 3x2 factorial experiment 72 Large White type weaner pigs were individually and restrictedly fed, from 501b (22–7 kg) to approximately 1601b (72–7 kg) live weight, iso-nitrogenous (16% crude protein) maize-based diets (as wet mashes with 2:1 ratios of water to dry food) containing 0–15%, 0–22% or 0–29% tryptophan and either 0–85% or 0–97% lysine. Overall, for the period in its entirety and in the period from the start to 110 lb (50–0 kg) live weight, the diets containing 0–22% and 0–29% tryptophan gave a similar performance. Together they gave a significantly superior performance compared with that obtained from the diets containing 0–15 % tryptophan. Pigs fed the diets containing 0–85 % lysine converted their food better and grew faster than pigs fed the diets containing 0–97 % lysine. These differences were significant (P <0–05) for both parameters in the period from 110 lb (50–0 kg) live weight to the finish of the experiment at 1601b (72–5 kg) live weight and significant (P <0–05) for efficiency of food conversion in the overall experimental period.

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