THE ADRENAL REPONSE OF HAMSTERS, GERBILS AND RATS TO EXOGENOUS CORTICOTROPHIN OR UNILATERAL ADRENALECTOMY

1967 ◽  
Vol 54 (2) ◽  
pp. 257-262 ◽  
Author(s):  
Paul F. Robinson ◽  
Russel J. Reiter

ABSTRACT Either unilateral or sham adrenalectomy caused a marked decrease in the ascorbic acid content of the remaining adrenal gland of the rat. An even greater drop of this constituent was obtained one hour after the administration of 10 IU of corticotrophin. Rat adrenal cholesterol was somewhat less responsive to the above treatment. Unilateral or sham adrenalectomy had no significant effect on adrenal ascorbic acid or cholesterol in the hamster. Twenty IU of corticotrophin caused a 20% drop in hamster adrenal cholesterol whereas 10 IU did not. The response of the Mongolian gerbil to corticotrophin or adrenalectomy, either unilateral or sham, was approximately the same as that of the rat.

1957 ◽  
Vol 35 (11) ◽  
pp. 929-933 ◽  
Author(s):  
C. N. H. Long ◽  
M. F. M. Bonnycastle

The pattern of secretion of adrenocorticotrophic hormone (ACTH) has been studied by opening the pituitary fossa of rats 36 hours before unilateral adrenalectomy. At selected intervals afterwards, the pituitary gland was removed and the effect on the fall in the ascorbic acid content of the remaining adrenal gland was determined. It was found that ACTH discharge is initiated with great rapidity and that the secretory pattern is a biphasic one. The first phase continues for about 5 minutes and then declines. It is succeeded by a second period of secretion that is much more prolonged. It is suggested that these results support the view that both a neural or neural–humoral and a purely humoral mechanism participate in the regulation of ACTH secretion.


1957 ◽  
Vol 35 (1) ◽  
pp. 929-933
Author(s):  
C. N. H. Long ◽  
M. F. M. Bonnycastle

The pattern of secretion of adrenocorticotrophic hormone (ACTH) has been studied by opening the pituitary fossa of rats 36 hours before unilateral adrenalectomy. At selected intervals afterwards, the pituitary gland was removed and the effect on the fall in the ascorbic acid content of the remaining adrenal gland was determined. It was found that ACTH discharge is initiated with great rapidity and that the secretory pattern is a biphasic one. The first phase continues for about 5 minutes and then declines. It is succeeded by a second period of secretion that is much more prolonged. It is suggested that these results support the view that both a neural or neural–humoral and a purely humoral mechanism participate in the regulation of ACTH secretion.


Planta Medica ◽  
2011 ◽  
Vol 77 (12) ◽  
Author(s):  
A Haskovic ◽  
A Copra Janicijevic ◽  
A Topcagic ◽  
L Klepo ◽  
A Kapur ◽  
...  

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Dalila Lopes da Silva ◽  
Renato de Mello Prado ◽  
Luis Felipe Lata Tenesaca ◽  
José Lucas Farias da Silva ◽  
Ben-Hur Mattiuz

AbstractCalcium (Ca) deficiency in cabbage plants induces oxidative damage, hampering growth and decreasing quality, however, it is hypothesized that silicon (Si) added to the nutrient solution may alleviate crop losses. Therefore, this study aims at evaluating whether silicon supplied in the nutrient solution reduces, in fact, the calcium deficiency effects on cabbage plants. In a greenhouse, cabbage plants were grown using nutrient solutions with Ca sufficiency and Ca deficiency (5 mM) without and with added silicon (2.5 mM), arranged as a 2 × 2 factorial in randomized blocks, with five replications. At 91 days after transplanting, the plants were harvested for biological evaluations. In the treatment without added Si, Ca deficiency promoted oxidative stress, low antioxidant content, decreased dry matter, and lower quality leaf. On the other hand, added Si attenuated Ca deficiency in cabbage by decreasing cell extravasation while increasing both ascorbic acid content and fresh and dry matter, providing firmer leaves due to diminished leaf water loss after harvesting. We highlighted the agronomic importance of Si added to the nutrient solution, especially in crops at risk of Ca deficiency.


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