ESTIMATION OF ANTIDIURETIC HORMONE IN THE URINE OF HEALTHY SUBJECTS AND PATIENTS WITH INAPPROPRIATE SECRETION OF VASOPRESSIN (SCHWARTZ-BARTTER SYNDROME)

1967 ◽  
Vol 54 (1) ◽  
pp. 113-121 ◽  
Author(s):  
W. Ruch

ABSTRACT The excretion of antidiuretic hormone in the urine was determined in healthy subjects and patients with inappropriate secretion of vasopressin. The antidiuretic hormone was extracted by means of an ion exchanger and assayed in hydrated rats under alcohol anaesthesia. The urine of patients with inappropriate antidiuretic hormone secretion shows a higher antidiuretic activity than that of normal subjects.

1983 ◽  
Vol 143 (4) ◽  
pp. 406-410 ◽  
Author(s):  
E. G. Lever ◽  
S. A. Stansfeld

SummaryA case of tuberculous Addison's disease presenting with psychosis, profound hyponatraemia, and detectable plasma antidiuretic hormone is reported. Clinical and biochemical improvement after corticosteroid replacement was followed by relapse with further psychosis and inappropriate antidiuretic hormone secretion: both were promptly reversed by demethylchlortetracycline. The association of psychological symptoms with Addison's disease, the role of anti-diuretic hormone secretion in Addison's disease, and the inter-relationship between Addison's disease, psychosis and anti-diuretic hormone secretion are discussed.


1979 ◽  
Vol 24 (3) ◽  
pp. 225-231 ◽  
Author(s):  
C.J. Jose ◽  
S. Mehta ◽  
J. Perez-Cruet

We have reviewed 14 cases of water intoxication in psychiatric patients. In these cases the possibility of the syndrome of inappropriate antidiuretic hormone secretion (SIADH) was suspected or diagnosed. The SIADH should be suspected in psychotic patients who drink water excessively, develop seizures, disorientation and deterioration of mental status.


2021 ◽  
Vol 49 (2) ◽  
pp. 030006052098565
Author(s):  
Cai-Fu Zhao ◽  
Su-Fen Zhao ◽  
Ze-Qing Du

Small cell carcinoma of the cervix is a rare malignant tumor in the clinical setting. Clinical manifestations of this tumor are mostly similar to those of normal types of cervical cancer. Small cell carcinoma of the cervix only shows symptoms of neuroendocrine tumors, such as syndrome of inappropriate antidiuretic hormone secretion (SIADH). Most of the hyponatremia caused by SIADH can be managed after removal of the cause. Hyponatremia is a predictor of poor prognosis and can be used as an indicator of partial recurrence. We report a case of small cell carcinoma of the cervix complicated by SIADH. Our patient presented with irregular vaginal bleeding after menopause. After one cycle of chemotherapy, there was trembling of the limbs, and a laboratory examination showed low Na+ and low Cl− levels. After limited water intake, intravenous hypertonic saline, and intermittent diuretic treatment, the patient’s blood Na+ levels returned to normal. After a radical operation, the above-mentioned symptoms disappeared.


2014 ◽  
Vol 2014 (apr11 1) ◽  
pp. bcr2013202575-bcr2013202575
Author(s):  
P. Barros Alcalde ◽  
A. Gonzalez Quintela ◽  
M. Pena Seijo ◽  
A. Pose-Reino

The Lancet ◽  
2021 ◽  
Vol 397 (10290) ◽  
pp. 2194
Author(s):  
Charidimos Tsagkas ◽  
Silke Schäfer ◽  
Annette Baumgartner ◽  
Jannis Müller ◽  
Tim Sinnecker ◽  
...  

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