THE URINARY EXCRETION OF 16-EPI-OESTRIOL DURING THE MENSTRUAL CYCLE, IN POSTMENOPAUSAL WOMEN, AND IN MALES

1962 ◽  
Vol 40 (3_Suppl) ◽  
pp. S83
Author(s):  
W. Nocke
1987 ◽  
Vol 116 (1) ◽  
pp. 145-149 ◽  
Author(s):  
Jocelyne Brun ◽  
Bruno Claustrat ◽  
Michel David

Abstract. Nocturnal urinary excretion of melatonin, LH, progesterone and oestradiol was measured by radioimmunoassay in nine normal women during a complete cycle. In addition, these hormonal excretions were studied in two women taking an oral contraceptive. A high within-subject coefficient of variation was observed for melatonin excretion in the two groups. In the nine normal cycling women, melatonin excretion was not decreased at the time of ovulation, but was significantly increased during the luteal phase compared with that of the follicular phase (P < 0.01). These data are consistent with a positive relationship between melatonin and progesterone during the luteal phase. In the two women under an oral contraceptive, melatonin excretion was found within the same range as for the other nine. The results are discussed in terms of pineal investigation in human.


1961 ◽  
Vol 38 (2) ◽  
pp. 276-284 ◽  
Author(s):  
Robert E. Baker ◽  
Joseph W. Goldzieher

ABSTRACT A simple and quantitative procedure for the extraction and measurement of total urinary radioactive steroid metabolites is described. The urinary excretion of topically applied 14C oestrone + 3H 17β-oestradiol and of 14C cortisol (11β, 17, 21-trihydroxy-pregn-4-ene-3, 20-dione) alone was studied with and without the addition of carrier oestrone, in both premenopausal and postmenopausal women. Over 80 percent of the cortisol, 7.5 to 41 percent of the oestrone, and 3.4 to 20 percent of the 17β-oestradiol metabolites appeared in the urine within 72 hours. Neither the ovarian status of the subjects nor the presence of carrier oestrone appeared to influence these results.


2019 ◽  
Vol 495 ◽  
pp. 198-204 ◽  
Author(s):  
Sara J.E. Verdonk ◽  
Hubert W. Vesper ◽  
Frans Martens ◽  
Patrick M. Sluss ◽  
Jacquelien J. Hillebrand ◽  
...  

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