scholarly journals SURFACE CHARACTERISTICS OF DPPC MONOLAYERS DEPOSITED FROM TITANIUM DIOXIDE–CHITOSAN–HYALURONIC ACID SUBPHASES ON A GLASS SUPPORT

Author(s):  
Agata Ładniak ◽  
◽  
Małgorzata Jurak ◽  
Agnieszka Ewa Wiącek ◽  
◽  
...  
2019 ◽  
Vol 3 (1) ◽  
pp. 15 ◽  
Author(s):  
Agata Ładniak ◽  
Małgorzata Jurak ◽  
Agnieszka Ewa Wiącek

The investigations were carried out to determine wettability of the 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) monolayers transferred from the liquid subphases containing chitosan (Ch), hyaluronic acid (HA), and/or titanium dioxide (TiO2) to a glass support by means of the Langmuir–Blodgett (LB) technique. For comparative purposes, the analysis of the plates surfaces emerged from the analogous subphases without the phospholipid film was also made. Characterization of the DPPC monolayers was based on the contact angle measurements using three test liquids (water, formamide, diiodomethane) and a simulated body fluid (SBF) solution in which the concentration of ions was close to that of human plasma. After deposition of the DPPC monolayers on the glass plates, a significant increase in the contact angles of all the probe liquids was observed compared to the plates pulled out from the given subphase without floating DPPC. The presence of phospholipid monolayer increased the hydrophobic character of the surface due to orientation of its molecules with hydrocarbon chains towards the air. In addition, the components of the subphase attached along with DPPC to the glass support modify the surface polarity. The largest changes were observed in the presence of TiO2.


2007 ◽  
Vol 19 (02) ◽  
pp. 91-97
Author(s):  
Bo-Yi Yu ◽  
Po-Ya Chen ◽  
Yi-Ming Sun ◽  
Tai-Horng Young

Polyhydroxyalkanoates (PHAs) is a newer family of biomaterials for tissue engineering applications. The objective of this study is to investigate the behaviors of human Schwann cells-like (hSCs-like) on various PHA films. The surface characteristics of PHA films were varied by the content of 3-hydroxyvalerate (HV) or 3-hydroxyhexanoate (HHx) and by the film preparation methods such as compression-molding and solvent-casting. Hyaluronic acid (HA) and poly(L-lysine) (PLL) were further applied on to improve the growth of hSCs-like on PHA membranes. The hSCs-like isolated from human body (MATERIALS AND METHODS) would have strong metabolic activities and produce many extracellular matrix (ECM). When HV content increased, there was a reduction in the crystallinity and the hydrophoicity of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) membranes. Despite that these different surface characteristics did not show significant effect on the metabolic activities of hSCs-like, these would affect adhering HA. Hyaluronic acid (HA)-coated PHA membranes could improve the metabolic activities and decrease the death ratio of hSCs-like. However, the condition of PLL coating has no obvious influence on the activities of hSCs.


2021 ◽  
Vol 105 (1) ◽  
pp. 61-68
Author(s):  
Nataliya I. Globa ◽  
Yurii V. Shmatok ◽  
Tatyana V. Lisnycha ◽  
Sviatoslav A. Kirillov

The paper presents the results of studies of nanosized titanium dioxide (TiO2) samples synthesized by alkaline hydrolysis. The surface properties of the samples were modified using high-temperature annealing. As a result, samples with a specific surface area of 31-203 m2/g were obtained. The specific capacity of TiO2 in lithium and sodium cells was determined. It is noted that the nature of the curves obtained, the specific capacity and its stability during cycling depend on the nature of the alkali metal cation and the surface properties of TiO2.


2021 ◽  
Vol 11 (1) ◽  
pp. 123-128
Author(s):  
Shiqiang Ma ◽  
Donghui Guo ◽  
Qiuling Shi ◽  
Xiaoming Li

The aforementioned study emphasis on formulation of Dexamethasone and Hyaluronic acid (DHA) loaded microspheres for intra-articulate injection at hip region to cure arthritic condition. DHA microspheres were formulated by solvent evaporation technique. The microspheres were found with smooth, regular surface characteristics. The loading and encapsulation efficiencies were also found higher. The in vitro release was found to be 15.12% for initial 24 hrs while 97.65% up to 25 days. Such microspheres were injected to hip region of Adult male new Zealand Rabbits (2.5–3 kg) to observe anti arthritic effect. The study result showed excellent ability of microsphere in order to treat arthritis. Therefore the results obtained concluded effectiveness of DHA microspheres in treating arthritic disease.


2012 ◽  
Vol 734 ◽  
pp. 226-236 ◽  
Author(s):  
Henry H. Mungondori ◽  
Lilian Tichagwa

The sol gel synthesis method was used to prepare carbon and nitrogen doped titanium dioxide (TiO2) photo-catalyst using titanium tetrachloride (TiCl4) as the precursor. Doping was carried out to modify the absorption band edge of titanium dioxide. To avert the problem associated with use of powder TiO2, the photo-catalyst was immobilized on glass support using tetraethyl orthosilicate (TEOS), which served as a binder and precursor for silicon dioxide (SiO2). The prepared photo-catalytic materials were characterized by FT-IR, XRD, TEM, BET and DRS. The photo-catalytic efficiency of titanium dioxide immobilized on glass support was evaluated using the degradation of methyl orange (MeO) and phenol red (PRed) under ultraviolet and visible light irradiation. Doping with carbon and nitrogen, and incorporation of silicon dioxide into the titanium dioxide matrix allowed utilization of visible light by the prepared TiO2-SiO2nanocomposites. Photo-degradation tests were carried out for doped and undoped photo-catalyst. An increased rate of photo-oxidation of methyl orange and phenol red was observed under visible light irradiation as compared to UV light irradiation.


Adsorption ◽  
2019 ◽  
Vol 25 (3) ◽  
pp. 469-476 ◽  
Author(s):  
Agata Ładniak ◽  
Małgorzata Jurak ◽  
Agnieszka Ewa Wiącek

2019 ◽  
pp. 302-311
Author(s):  
Adriana DM Del Monaco ◽  
Eliana AR Duek ◽  
Aron JP Andrade ◽  
Sonia MM Malmonge

Coronary artery disease has been leading cause of death in the world, angioplasty stent implantation is an important strategy in these cases. Studies indicate that biodegradability, immobilization of antiproliferatives and bioactive molecules in stents, are the characteristics of future generations of these devices. Amongst them, hyaluronic acid contributes to decrease of the aggregation and proliferation of cells between artery layers and the implanted device. For this purpose, poly (L-lactic acid) (PLLA) bioresorbable coronary stents with hyaluronic acid (HA) grafting in poly (LD- lactic acid) (PLDLA) were developed. The models were characterized as their thermal properties with Thermogravimetric Analysis (TGA) and Differential Scanning Calorimetric Analysis (DSC), Fourier Transform Infrared Spectrometry (FTIR), Wettability, with study of Contact Angle using Water swelling. PLDLA ADH-modified HA grafting presented more hydrophilic surface characteristics, ideal for coating material of this devices. In conclusion, grafting of hyaluronic acid in the PLDLA matrices confirmed, by technics used at this project. The coating of models of PLLA with PLDLA-HAADH made by dip coating technic.


Sign in / Sign up

Export Citation Format

Share Document