scholarly journals p110α of PI3K is necessary and sufficient for quiescence exit in adult muscle satellite cells

2018 ◽  
Vol 37 (8) ◽  
Author(s):  
Gang Wang ◽  
Han Zhu ◽  
Chenghao Situ ◽  
Lifang Han ◽  
Youqian Yu ◽  
...  
Keyword(s):  
Satellite Cells ◽  
Muscle Satellite Cells ◽  
Adult Muscle ◽  
Necessary And Sufficient

Asymmetric division and cosegregation of template DNA strands in adult muscle satellite cells

2006 ◽  
Vol 8 (7) ◽  
pp. 677-682 ◽  
Author(s):  
Vasily Shinin ◽  
Barbara Gayraud-Morel ◽  
Danielle Gomès ◽  
Shahragim Tajbakhsh
Keyword(s):  
Satellite Cells ◽  
Asymmetric Division ◽  
Muscle Satellite Cells ◽  
Adult Muscle ◽  
Dna Strands ◽  
Template Dna

scholarly journals Identification and functional characterization of muscle satellite cells in Drosophila

eLife ◽  
2017 ◽  
Vol 6 ◽  
Author(s):  
Dhananjay Chaturvedi ◽  
Heinrich Reichert ◽  
Rajesh D Gunage ◽  
K VijayRaghavan
Keyword(s):  
Stem Cells ◽  
Muscle Fiber ◽  
Satellite Cells ◽  
Genetic Model ◽  
Functional Characterization ◽  
Model Systems ◽  
Muscle Stem Cells ◽  
Muscle Satellite Cells ◽  
Adult Muscle ◽  
Functional Features

Work on genetic model systems such as Drosophila and mouse has shown that the fundamental mechanisms of myogenesis are remarkably similar in vertebrates and invertebrates. Strikingly, however, satellite cells, the adult muscle stem cells that are essential for the regeneration of damaged muscles in vertebrates, have not been reported in invertebrates. In this study, we show that lineal descendants of muscle stem cells are present in adult muscle of Drosophila as small, unfused cells observed at the surface and in close proximity to the mature muscle fibers. Normally quiescent, following muscle fiber injury, we show that these cells express Zfh1 and engage in Notch-Delta-dependent proliferative activity and generate lineal descendant populations, which fuse with the injured muscle fiber. In view of strikingly similar morphological and functional features, we consider these novel cells to be the Drosophila equivalent of vertebrate muscle satellite cells.

scholarly journals Identification and Functional Characterization of Muscle Satellite Cells in Drosophila

2016 ◽  
Author(s):  
Dhananjay Chaturvedi ◽  
Heinrich Reichert ◽  
Rajesh Gunage ◽  
K. VijayRaghavan
Keyword(s):  
Stem Cells ◽  
Muscle Fiber ◽  
Satellite Cells ◽  
Genetic Model ◽  
Functional Characterization ◽  
Model Systems ◽  
Muscle Stem Cells ◽  
Muscle Satellite Cells ◽  
Adult Muscle ◽  
Functional Features

AbstractWork on genetic model systems such as Drosophila and mouse has shown that the fundamental mechanisms of myogenesis are remarkably similar in vertebrates and invertebrates. Strikingly however, satellite cells, the adult muscle stem cells that are essential for the regeneration of damaged muscles in vertebrates, have not been reported in invertebrates. In this study we show that lineal descendants of muscle stem cells are present in adult muscle of Drosophila as small, unfused cells located superficially and in close proximity to the mature muscle fibers. Normally quiescent, following muscle fiber injury, we show that these cells express Zfh1- cells and engage in Notch-Delta dependent proliferative activity and generate lineal descendant populations, which fuse with the injured muscle fiber. In view of strikingly similar morphological and functional features, we consider these novel cells to be the Drosophila equivalent of vertebrate muscle satellite cells.

scholarly journals STAT3 Regulates Self-Renewal of Adult Muscle Satellite Cells during Injury-Induced Muscle Regeneration

Cell Reports ◽  
2016 ◽  
Vol 16 (8) ◽  
pp. 2102-2115 ◽  
Author(s):  
Han Zhu ◽  
Fang Xiao ◽  
Gang Wang ◽  
Xiuqing Wei ◽  
Lei Jiang ◽  
...  
Keyword(s):  
Satellite Cells ◽  
Muscle Regeneration ◽  
Self Renewal ◽  
Muscle Satellite Cells ◽  
Adult Muscle
Sign in / Sign up

Export Citation Format

Share Document