scholarly journals Oral lichen planus involving the palate: Case report and review of literature

2020 ◽  
Vol 3 (2) ◽  
pp. 89-92
Author(s):  
Shaheen Ahmed ◽  
Ali Alzubaidee
Keyword(s):  
Lichen Planus ◽  
Buccal Mucosa ◽  
Oral Lichen Planus ◽  
Chief Complaint ◽  
Burning Sensation ◽  
Oral Lesions ◽  
Review Of Literature ◽  
Spicy Food ◽  
Immune Mediated ◽  
Oral Lichen

planus is a mucocutaneous disease affecting approximately 1.5 to 2% of the world popu-lation. Women are most of ten affected and lichen planus is usually reported in individuals over 50 years of age The etiology of lichen planus is unknown at present and the disorder has been classified as a chronic disease of immune-mediated pathogenesis. The oral lesions are usually bilateral and involve the buccal mucosa in about 90 per cent of all cases. In descending order of frequency the tongue, gingivae, alveolar ridge, lips, and less commonly the palate may also be affected. In this paper , we are presented a case , 65-year-old female patient who came to de-partment of Oral and Maxillofacial Medicine in Khanzad Center with a chief complaint of burn-ing sensation of the mouth especially hard palate, bilateral buccal mucosa and lower anterior gingiva for about 10 years duration, aggravated by hot and spicy food. The diagnosis was con-firmed by biopsy as lichen planus. The skin was not involved lesion. Keywords: Oral lichen planus, Palatal lichen planus, Burning sensation, Buccal mucosa

scholarly journals Oral Lichen Planus and Polycythemia: Possible Association

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Yassine Oueslati ◽  
Raouaa Belkacem Chebil ◽  
Haifa Regaieg ◽  
Lamia Oualha ◽  
Nabiha Douki
Keyword(s):  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Scientific Literature ◽  
Early Stage ◽  
Cell Mass ◽  
Chronic Inflammatory Disease ◽  
Oral Lesions ◽  
Immune Mediated ◽  
Immune Dysfunctions ◽  
Oral Lichen

Oral lichen planus is a chronic inflammatory disease of established immune-mediated pathogenesis that affects the oral mucosa. Polycythemia is a nonaggressive myeloproliferative disorder, characterized by an increase in red blood cell mass, often with uncontrolled production of granulocytes and platelets. Their association was rarely mentioned in the scientific literature. The aim of this paper was to report their occurrence in a 52-year-old male patient. Although a casual connection cannot be excluded, both diseases share many similarities in the immune dysfunctions involved in their pathogenesis and their clinical features. Such a hypothesis remains to be demonstrated by further studies. The presence of oral lesions should alert the clinicians in the process of identifying and early diagnosing these diseases. Thus, complications can be prevented and treatment can be started at an early stage, avoiding further damage.

scholarly journals ORAL LICHEN PLANUS – A CLINICAL AND HISTOPATHOLOGICAL STUDY

2021 ◽  
pp. 63-64
Author(s):  
Minha Majeed Kak ◽  
Priyanka Rastogi ◽  
Sachin Kumar ◽  
Arya Jyoti
Keyword(s):  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Skin Lesions ◽  
Primary Lesion ◽  
Burning Sensation ◽  
Histopathological Study ◽  
Oral Lesions ◽  
Main Symptom ◽  
Serious Disease ◽  
Oral Lichen

Lichen planus is one of the most common dermatologic 1 lesions to manifest in the oral cavity . The importance of understanding this disease lies in the fact that a large percentage of these cases present only oral lesions. Also the different clinical forms mimic some other more serious disease. The precise aetiology of lichen planus still remains unclear with recent works suggesting an autoimmune role. The skin lesions in lichen planus are distinctive and the primary lesion is a small, angular, flat-topped papule which may be discrete or gradually coalesce into large plaques.The oral lesions are highly variable and can be described as popular, annular, reticular, plaque, verrucuous, atrophic, 2 erosive, and ulcerative and vesiculo-bullous types .The main symptom is burning sensation of the affected areas.

scholarly journals Histopathological specialized staining of oral lichen planus-induced fibrotic changes and surgical treatment of associated restricted mouth opening: a case report

2021 ◽  
Vol 45 (1) ◽  
Author(s):  
Atsushi Shudo
Keyword(s):  
Surgical Treatment ◽  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Histopathological Examination ◽  
Mouth Opening ◽  
Ki 67 ◽  
Collagen Formation ◽  
Immune Mediated ◽  
Cytokeratin 13 ◽  
Oral Lichen

Abstract Background Oral lichen planus is a chronic inflammatory and immune-mediated disease that affects the oral mucosa. Recent findings have suggested that oral lichen planus is often associated with submucosal fibrotic changes. Fibrotic changes in the buccal submucosa may cause restricted mouth opening. This report discusses the histopathological examination (including specialized staining) and surgical treatment for oral lichen planus-induced fibrotic changes. Case presentation Here, we describe a 63-year-old woman who had oral lichen planus with fibrotic changes. Her maximum mouth opening distance was approximately 30 mm due to submucosal fibrotic changes, and she exhibited gradual fibrosis progression. Histological examinations were performed to assess the oral lichen planus-induced fibrotic changes. Then, double Z-plasty were performed as treatment for restricted mouth opening. The immunohistochemical staining results were negative for cytokeratin 13 and positive in some layers for cytokeratin 17 and Ki-67/MIB-1. Masson's trichrome staining showed enhanced collagen formation. Postoperative mouth opening training enabled the patient to achieve a mouth opening distance of > 50 mm. Conclusion Our findings suggest that histopathological examination with specialized staining can aid in the evaluation of oral lichen planus-induced fibrotic changes, and that Z-plasty is effective for the treatment of restricted mouth opening due to oral lichen planus.

Dysbiosis of oral buccal mucosa microbiota in patients with oral lichen planus

Oral Diseases ◽  
2017 ◽  
Vol 23 (5) ◽  
pp. 674-682 ◽  
Author(s):  
Y He ◽  
D Gong ◽  
C Shi ◽  
F Shao ◽  
J Shi ◽  
...  
Keyword(s):  
Lichen Planus ◽  
Buccal Mucosa ◽  
Oral Lichen Planus ◽  
Oral Lichen

scholarly journals TANTANGAN FARMAKOLOGI PENGGUNAAN STEROID TOPIKAL PADA PASIEN ORAL LICHEN PLANUS

2019 ◽  
Vol 6 (1) ◽  
pp. 30
Author(s):  
Revi Nelonda ◽  
Nanan Nur’aeny ◽  
Irna Sufiawati
Keyword(s):  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Clinical Signs ◽  
Topical Steroid ◽  
Topical Steroids ◽  
First Line ◽  
Spicy Food ◽  
Diffuse Erythema ◽  
Chronic Autoimmune Disease ◽  
Oral Lichen

Background: Oral lichen planus (OLP) is a chronic autoimmune disease sprinkled by T cells on the oral mucosal surface. The goal of OLP treatment is to eliminate erythema, ulceration and relieve symptoms. Corticosteroids are the first line in the treatment of OLP, either systemically or topically. The problem arises when using topical steroids, namely the time of topical steroid attachment to the oral mucosa, especially in cases of OLP with clinical desquamative gingivitis. Some studies suggest that the use of individual gingival tray can overcome this problem. Objective: To provide information on topical steroid use in OLP cases with desquamative gingivitis clinical signs.Case Management: Women, age 31, complain that pain with burning on the lips and mouth is aggravated by spicy food. Intraoral examination shows irregular white plaques on the buccal, labial and dorsal mucosa of the tongue accompanied by diffuse erythema in the anterior gingiva of the upper and lower jaws. Patients diagnosed with OLP. Lesions improve 3 months after topical steroid administration, except lesions on the gingiva. Gingival individual tray is then used to obtain adequate attachment of topical steroids on the gingiva surface. The gingiva showed significant improvement after a month later.Conclusion: The use of topical steroid concoctions applied to the gingival individual tray is effective in treating OLP lesions especially with clinical signs of desquamative gingivitis.

scholarly journals Case reports of two clinical forms of oral lichen planus with review of literature

2018 ◽  
Vol 5 (1) ◽  
pp. 19-22
Author(s):  
Tejavathi Nagaraj ◽  
C. K. Sumana ◽  
Arundhati Biswas ◽  
Haritma Nigam
Keyword(s):  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Case Reports ◽  
Review Of Literature ◽  
Clinical Forms ◽  
Oral Lichen

Clinical–pathologic Agreement for Oral Lesions in an Oral Medicine Setting

2016 ◽  
Vol 2 (1) ◽  
pp. 1-10 ◽  
Author(s):  
Alessandro Villa ◽  
Francesco Nordio ◽  
Laura Strohmenger ◽  
Silvio Abati
Keyword(s):  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Weighted Kappa ◽  
Mucous Membrane Pemphigoid ◽  
Histopathological Diagnosis ◽  
Severe Dysplasia ◽  
Oral Lesions ◽  
Oral Medicine ◽  
Squamous Papilloma ◽  
Oral Lichen

Background: Histopathological examination remains the gold standard for the diagnosis of oral mucosal lesions. To date little is known on the clinical–pathologic agreement for oral lesions diagnosed by oral medicine experts.  Objective: This retrospective study attempts to quantify the clinical–pathologic agreement for oral lesions diagnosed by oral medicine experts. Methods: Data were collected retrospectively from the medical records of all new oral medicine consultations. The clinical diagnosis provided by an oral medicine expert was compared to the histopathological diagnosis. Clinical–pathologic agreement was estimated as the percentage agreement and was measured using weighted Kappa. Results: The most common oral lesions were oral lichen planus (34.7%), traumatic fibroma (23.4%), squamous cell carcinoma (SCC) or severe dysplasia (6.7%), mucous membrane pemphigoid (MMP) (5.7%), leukoplakia (5.6%) and squamous papilloma (4.3%). The overall clinical–pathologic agreement for all lesions had a weighted kappa of 0.81 [95%CI 0.78% to 0.85%]. The concordance for the most common oral lesions in the study population was 90.2%, with a weighted kappa of 0.88 [95%CI 0.85% to 0.92%]. The clinical–pathologic agreement for SCC/severe dysplasia was 78.7%, for traumatic fibroma 91.4%, for leukoplakia 97.4%, for oral lichen planus 93.8%, for squamous papilloma 96.7% and for MMP 65%. Conclusions: The overall concordance between clinical and histopathological diagnosis for oral lesions was excellent. Dentists have the unique opportunity to refer patients to oral medicine experts for diagnosis and management of oral diseases. Given their expertise patients may require fewer visits for diagnostic purposes.

scholarly journals Familial oral lichen planus in a 3-year-old boy: a case report with eight years of follow-up

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Fang Wang ◽  
Ya-Qin Tan ◽  
Jing Zhang ◽  
Gang Zhou
Keyword(s):  
Lichen Planus ◽  
Oral Mucosa ◽  
Buccal Mucosa ◽  
Oral Lichen Planus ◽  
Familial Aggregation ◽  
Pediatric Population ◽  
Case Presentation ◽  
Oral Lichen

Abstract Background Oral lichen planus (OLP) is a chronic mucocutaneous disease characterized by adult predominance and a prolonged course. However, it is rare in the pediatric population with familial aggregation. Case presentation A 3-year-old boy presented with pain and irritation on the oral mucosa while contacting spicy food for 2 months. Oral examination showed widespread whitish reticular and papular lesions on the lips, the dorsum of the tongue, and bilateral buccal mucosa, with diffuse erosions covered with pseudomembrane on the buccal mucosa. The boy’s parents were examined to exhibit white reticular and plaque-like lesions on their oral mucosa. The three patients were clinically diagnosed as affected by OLP and histopathologically confirmed. The boy underwent topical treatment with recombinant bovine basic fibroblast growth factor (rb-bFGF) gel, and oral lesions gradually resolved and healed. Neither of his parents received treatment. During the subsequent follow-ups, none of three patients underwent any medical treatment. Fortunately, their lesions had almost faded over 8 years. Conclusions Our case emphasizes that pediatric OLP should be recorded with family history. Besides, long-term periodic follow-up is recommended in pediatric patients with OLP for monitoring any changes in lesions.

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