scholarly journals Case reports of two clinical forms of oral lichen planus with review of literature

2018 ◽  
Vol 5 (1) ◽  
pp. 19-22
Author(s):  
Tejavathi Nagaraj ◽  
C. K. Sumana ◽  
Arundhati Biswas ◽  
Haritma Nigam
Keyword(s):  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Case Reports ◽  
Review Of Literature ◽  
Clinical Forms ◽  
Oral Lichen

Oral health–related quality of life in different clinical forms of oral lichen planus

2019 ◽  
Vol 24 (1) ◽  
pp. 301-308 ◽  
Author(s):  
Ioanina Parlatescu ◽  
Mihaela Tovaru ◽  
Carmen Larisa Nicolae ◽  
Ruxandra Sfeatcu ◽  
Andreea Cristiana Didilescu
Keyword(s):  
Quality Of Life ◽  
Oral Health ◽  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Health Related Quality ◽  
Clinical Forms ◽  
Related Quality ◽  
Health Related ◽  
Oral Lichen

Efficacy of Topical Calcineurin Inhibitors in Lichen Planus

2012 ◽  
Vol 16 (4) ◽  
pp. 221-229 ◽  
Author(s):  
Michael Samycia ◽  
Andrew N. Lin
Keyword(s):  
Lichen Planus ◽  
Strong Evidence ◽  
Oral Lichen Planus ◽  
Case Reports ◽  
Calcineurin Inhibitors ◽  
Double Blind ◽  
Tacrolimus Ointment ◽  
Topical Tacrolimus ◽  
Topical Calcineurin Inhibitors ◽  
Oral Lichen

Background: Topical calcineurin inhibitors have been studied in many skin disorders, including lichen planus. Objective: To evaluate published reports of the use of topical calcineurin inhibitors in lichen planus. Methods: We searched PubMed, Ovid/Cochrane, and Embase using the keywords “tacrolimus,” “pimecrolimus,” “topical calcineurin inhibitors,” and “lichen planus.” Results: We examined 5 double-blind studies, 1 investigator-blinded study, 10 open prospective studies, 6 retrospective studies, and 28 case reports evaluating tacrolimus or pimecrolimus for oral, vulvovaginal, and cutaneous lichen planus. Conclusions: Strong evidence (double-blind and open studies) supports the use of topical tacrolimus ointment in oral lichen planus, with efficacy at least equal to topical clobetasol propionate 0.05% ointment. Treatment of oral lichen planus with topical tacrolimus ointment can result in demonstrable blood tacrolimus levels, but without clinically significant adverse events. Strong evidence (double-blind and open studies) supports the use of topical pimecrolimus 1% cream in oral lichen planus, with efficacy equal to that of topical triamcinolone acetonide 0.1% paste. For vulvovaginal lichen planus, pimecrolimus was superior to placebo in one double-blind study, and tacrolimus was effective in open studies. Only case reports support the efficacy of topical calcineurin inhibitors in cutaneous lichen planus.

scholarly journals Assessment of the Relationship Between Stress and Oral Lichen Planus: A Review of Literature

2016 ◽  
Vol 28 (2) ◽  
pp. 78-85 ◽  
Author(s):  
Farzaneh Agha Hosseini ◽  
Mahdieh Sadat Moosavi ◽  
Maryam Sadat Sadrzadeh Afshar ◽  
Nafiseh Sheykh Bahaei ◽  
◽  
...  
Keyword(s):  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Review Of Literature ◽  
The Relationship ◽  
Oral Lichen

scholarly journals Detection of Serum and Salivary VEGF among Patients with Different Clinical Forms of Oral Lichen Planus

2017 ◽  
Vol 63 (3) ◽  
pp. 2363-2368
Author(s):  
Nayroz Abdelfattah ◽  
Maha Abdelkawy ◽  
Olfat Shaker
Keyword(s):  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Clinical Forms ◽  
Oral Lichen

scholarly journals Efficacy of topical hyaluronic acid for symptomatic oral lichen planus: A systematic Review.

2021 ◽  
Vol 10 (4) ◽  
pp. 1-7
Author(s):  
Sadeq A. Al-Maweri ◽  
◽  
Rawan Alanazi ◽  
Mohammed Nasser Alhajj ◽  
Ammar Daer ◽  
...  
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Hyaluronic Acid ◽  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Randomized Clinical Trials ◽  
Case Reports ◽  
Clinical Signs ◽  
Case Series ◽  
Oral Lichen

Background: Oral lichen planus (OLP) is a chronic inflam-matory disorder with a potential of malignant transformation. Despite the extensive research on the topic, the management of OLP is still quite challenging, with no definitive cure. Objective: The present systematic review assessed the efficacy of topical hyaluronic acid in the management of OLP. Material and Methods: A comprehensive search of PubMed, Scopus, Web of Science and Google Scholar was carried out by two independent investigators. All randomized clinical trials that compared the efficacy of hyaluronic acid with other interventions and/or placebo in the management of OLP and fulfilled the following criteria were included: 1) OLP diagnosis was confirmed clinically and histopathologically, 2) the study included systemically healthy patients aged 15 years and older, 3) a minimum sample size of 10, and 4) reporting the main outcomes including pain, erythema, and ulcer size. Case reports, case series, reviews, animal studies, uncontrolled trials were excluded. Results: Four clinical trials involving 234 patients were included. Two studies compared hyaluronic acid with a topical corticosteroid, and two studies compared it with placebo. Only one of the four included studies was at low risk of bias. Overall, topical hyaluronic acid showed good efficacy in alleviating the signs and symptoms of OLP. Two studies found hyaluronic acid significantly more effective in reducing pain and improving clinical signs of OLP compared to placebo. Compared to topical corticosteroids, one study reported comparable results; and one study found hyaluronic acid to be superior to triamcinolone in reducing pain but inferior to triamcinolone in improving the healing time. Conclusion: The limited available evidence suggests that hyaluronic acid may have some benefits in the management of OLP. Further well-designed studies with adequate follow-up periods are highly recommended.

Sign in / Sign up

Export Citation Format

Share Document