Design of a Laboratory Experiment to Identify the Effects of Environmental Pollutants on Materials

2009 ◽  
pp. 279-279-13
Author(s):  
JW Spence ◽  
FH Haynie
Keyword(s):  
Laboratory Experiment ◽  
Environmental Pollutants

Polychlorinated biphenyl induced hepatocyte alterations

1987 ◽  
Vol 45 ◽  
pp. 716-717
Author(s):  
D.N. Collins ◽  
J.N. Turner ◽  
K.O. Brosch ◽  
R.F. Seegal
Keyword(s):  
Lipid Droplets ◽  
Wistar Rats ◽  
Homovanillic Acid ◽  
Polychlorinated Biphenyl ◽  
Corn Oil ◽  
Environmental Pollutants ◽  
Short Term ◽  
Pcb Congeners ◽  
Urinary Levels ◽  
The Brain

Polychlorinated biphenyls (PCBs) are a ubiquitous class of environmental pollutants with toxic and hepatocellular effects, including accumulation of fat, proliferated smooth endoplasmic recticulum (SER), and concentric membrane arrays (CMAs) (1-3). The CMAs appear to be a membrane storage and degeneration organelle composed of a large number of concentric membrane layers usually surrounding one or more lipid droplets often with internalized membrane fragments (3). The present study documents liver alteration after a short term single dose exposure to PCBs with high chlorine content, and correlates them with reported animal weights and central nervous system (CNS) measures. In the brain PCB congeners were concentrated in particular regions (4) while catecholamine concentrations were decreased (4-6). Urinary levels of homovanillic acid a dopamine metabolite were evaluated (7).Wistar rats were gavaged with corn oil (6 controls), or with a 1:1 mixture of Aroclor 1254 and 1260 in corn oil at 500 or 1000 mg total PCB/kg (6 at each level).

Susceptibility of Angoff Method to Judgmental Errors: A Laboratory Experiment

2006 ◽  
Author(s):  
Daren S. Protolipac ◽  
Lisa Finkelstein ◽  
John Kulas
Keyword(s):  
Laboratory Experiment ◽  
Angoff Method

Computers and Iatrocomplexities

1966 ◽  
Vol 05 (04) ◽  
pp. 167-171 ◽  
Author(s):  
L. E. Faer
Keyword(s):  
Twentieth Century ◽  
Cigarette Smoke ◽  
Environmental Pollutants ◽  
Genetic Composition ◽  
Koch’S Postulates ◽  
Lung Malignancies ◽  
Causative Agents ◽  
Disease Study ◽  
Multiple Etiology ◽  
Great Advance

Developments of disease hypotheses and conceptions of disease as philosophic entities have shown bursts of great advance. One just concluded includes emergence of bacteriology and virology culminating in Koch’s Postulates, which in the twentieth century were primary bases for disease study and colored all approaches to medicine.With recent extraordinary advances in technology, medicine faces great new obligations demanding fresh approaches and untrammeled thinking for solution of problems posed. It is clear that any approach to diseases and disabilities induced by exposures to environmental pollutants must take multiple etiology into account. For example, contributing to causation of lung malignancies one must list usual dusts, radioactivity, smog, auto exhausts, cigarette smoke and genetic composition. Consideration of plural factors in genesis of environmentally associated disease leads to the hypothesis of the incremental insult, a complex and difficult conception in which must be included provision for multiple causative agents, each contributing but a fraction toward total etiology^ Computers developed to their present refinement provide necessary tools for whatever complexity required to spawn and fructify hypotheses of inter-relating associations of incremental insults leading to pathology.

Investigation of discontinuous periodic signals using the measuring labview complex

2020 ◽  
pp. 72-79
Author(s):  
E.B. Solovyeva ◽  
◽  
Yu.M. Inshakov ◽  
Keyword(s):  
Fourier Series ◽  
Laboratory Experiment ◽  
Gibbs Phenomenon ◽  
Electrical Signals ◽  
Measuring Complex ◽  
Universal Measuring ◽  
Depth Study ◽  
Periodic Signals ◽  
Truncated Fourier Series

General approaches to the analysis of the Gibbs phenomenon for discontinuous periodic signals approximated by the truncated Fourier series are considered. Methods for smoothing the truncated Fourier series and improving its convergence are discussed. The software means for modeling is a universal measuring complex LabVIEW, which possesses a convenient environment for analyzing electrical signals, on the basis of this complex a laboratory experiment is carried out. The advantages of the measuring LabVIEW complex and its capabilities for in-depth study of discontinuous periodic signals are noted.

RESULTS OF THE LABORATORY EXPERIMENT OF THE RECEIVING WORKING BODY

2020 ◽  
Vol 2 (2) ◽  
pp. 20-31
Author(s):  
ANTON S. FIRSOV ◽  
◽  
ELENA S. BELYAKOVA ◽  
MARIA S. SUDAKOVA ◽  
◽  
...  
Keyword(s):  
Laboratory Experiment

EPEGENTIC TOXICOLOGY: PERSPECTIVES OF THE DEVELOPMENT

2018 ◽  
pp. 2-7
Author(s):  
G. A. Sofronov ◽  
E. L. Patkin
Keyword(s):  
Public Health ◽  
Life Cycle ◽  
Human Health ◽  
Chronic Exposure ◽  
Environmental Pollutants ◽  
Epigenetic Mechanisms ◽  
Epigenetic Changes ◽  
Mechanism Of Formation ◽  
Health Disorders ◽  
Time Periods

One of the complex problems of modern experimental toxicology remains the molecular mechanism of formation of human health disorders separated at different time periods from acute or chronic exposure to toxic environmental pollutants (ecotoxicants). Identifying and understanding what epigenetic changes are induced by the environment, and how they can lead to unfavorable outcome, are vital for protecting public health. Therefore, we consider it important a modern understanding of epigenetic mechanisms involved in the life cycle of mammals and assess available data on the environmentally caused epigenetic toxicity and, accordingly fledging epigenenomic (epigenetic) regulatory toxicology.

Service Provision on a Railway Network: A Laboratory Experiment

2012 ◽  
Author(s):  
Aurora García-Gallego ◽  
Nikolaos Georgantzis ◽  
Gerardo Vicente Sabater
Keyword(s):  
Laboratory Experiment ◽  
Service Provision ◽  
Railway Network
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