New Polymeric Materials for Temperature Controlled Release of Agricultural Chemicals

2008 ◽  
pp. 74-74-11
Author(s):  
L Greene ◽  
RF Stewart
Keyword(s):  
Controlled Release ◽  
Polymeric Materials ◽  
Agricultural Chemicals ◽  
Temperature Controlled

scholarly journals Drug release from thin films encapsulated by a temperature-responsive hydrogel

Soft Matter ◽  
2019 ◽  
Vol 15 (8) ◽  
pp. 1853-1859 ◽  
Author(s):  
Oliver Werzer ◽  
Stephan Tumphart ◽  
Roman Keimel ◽  
Paul Christian ◽  
Anna Maria Coclite
Keyword(s):  
Thin Films ◽  
Controlled Release ◽  
Drug Release ◽  
Temperature Responsive ◽  
Temperature Controlled ◽  
Drug Polymer Interaction ◽  
Polymer Interaction

Temperature-controlled release and study on the effects of the drug–polymer interaction and pH.

scholarly journals Microscale Polymer Bottles Corked with a Phase-Change Material for Temperature-Controlled Release

2013 ◽  
Vol 52 (40) ◽  
pp. 10468-10471 ◽  
Author(s):  
Dong Choon Hyun ◽  
Ping Lu ◽  
Sang-Il Choi ◽  
Unyong Jeong ◽  
Younan Xia
Keyword(s):  
Controlled Release ◽  
Phase Change ◽  
Phase Change Material ◽  
Temperature Controlled ◽  
Change Material

scholarly journals Oral Controlled Delivery of Natural Compounds Using Food-Grade Polymer Microparticles

2020 ◽  
Vol 01 ◽  
Author(s):  
Claudia Curcio ◽  
Angela Bonaccorso ◽  
Teresa Musumeci ◽  
Rosario Pignatello
Keyword(s):  
Drug Delivery ◽  
Controlled Release ◽  
Targeted Drug Delivery ◽  
Polymeric Materials ◽  
Herbal Remedies ◽  
Ph Change ◽  
Coating Materials ◽  
Food Grade ◽  
Targeted Drug

Background:: targeted drug delivery to colon is a strategical approach for the local cure of inflammation bowel diseases (IBD) and other syndromes like colon cancer. Research is actively focusing on possible alternative and safer therapies to conventional drugs, based on herbal remedies and other natural products. In particular, colon-targeted drug delivery systems (CDDS) offer the opportunity to protect the active compound along the way to the colon. Drug release and absorption, and even degradation should not occur in the stomach and small bowel, but a selective release should star once the system moves to the colonic area. Objective:: this work aims at evaluating the gastro-resistant properties of new food-grade methacrylic resins (Eudraguard®), used not as coating materials, but after the formation of microparticles, to achieve a delayed and targeted release of a model drug, resveratrol (RVT), to the ileo-colonic area. Methods:: microparticles were produced by an emulsion-solvent evaporation technique (ESE) and characterized by solid-state analytical methods. RVT release profiles were assessed in vitro using a pH-change procedure, able to simulate the transit of the carrier along the gastro-intestinal tract. Results:: Eudraguard® Biotic can form microparticles with a very high encapsulation efficiency for RVT; the polymeric matrix is able to limit the diffusion of the drug at gastric and gut pH conditions, while a higher release was achieved at pH 7.4. Conversely, using the Eudraguard® Control resin, alone or blended with the former polymer, did not allow to achieve a controlled release of RVT at the various pH values. Conclusion:: food-grade Eudraguard® matrices can be proposed, and would deserve further investigations, as polymeric materials for the preparation of micrometric matrices or pellets for the oral controlled release of natural active ingredients to the ileo-colonic area.

scholarly journals Stimulus-responsive liquids for encapsulation storage and controlled release of drugs from nano-shell capsules

2010 ◽  
Vol 8 (56) ◽  
pp. 451-456 ◽  
Author(s):  
Ming-Wei Chang ◽  
Eleanor Stride ◽  
Mohan Edirisinghe
Keyword(s):  
Drug Delivery ◽  
Controlled Release ◽  
Drug Release ◽  
Polymeric Materials ◽  
Controlled Drug Release ◽  
Ambient Conditions ◽  
Smart Polymer ◽  
Release Studies ◽  
Stimulus Responsive ◽  
New Strategy

Drug-delivery systems with a unique capability to respond to a given stimulus can improve therapeutic efficacy. However, development of such systems is currently heavily reliant on responsive polymeric materials and pursuing this singular strategy limits the potential for clinical translation. In this report, with a model system used for drug-release studies, we demonstrate a new strategy: how a temperature-responsive non-toxic, volatile liquid can be encapsulated and stored under ambient conditions and subsequently programmed for controlled drug release without relying on a smart polymer. When the stimulus temperature is reached, controlled encapsulation of different amounts of dye in the capsules is achieved and facilitates subsequent sustained release. With different ratios of the liquid (perfluorohexane): dye in the capsules, enhanced controlled release with real-time response is provided. Hence, our findings offer great potential for drug-delivery applications and provide new generic insights into the development of stimuli drug-release systems.

An intelligent multicompartmental system based on thermo-sensitive starch microspheres for temperature-controlled release of drugs

2010 ◽  
Vol 12 (4) ◽  
pp. 693-704 ◽  
Author(s):  
Gheorghe Fundueanu ◽  
Marieta Constantin ◽  
Paolo Ascenzi ◽  
Bogdan C. Simionescu
Keyword(s):  
Controlled Release ◽  
Temperature Controlled
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