Design and Fabrication of a 3D Scaffold for Tissue Engineering Bone

2008 ◽  
pp. 152-152-16 ◽  
Author(s):  
DW Hutmacher ◽  
SH Teoh ◽  
I Zein ◽  
KW Ng ◽  
J-T Schantz ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
3D Scaffold

Tissue Engineering: Biomimetic Concealing of PLGA Microspheres in a 3D Scaffold to Prevent Macrophage Uptake (Small 11/2016)

Small ◽  
2016 ◽  
Vol 12 (11) ◽  
pp. 1394-1394
Author(s):  
Silvia Minardi ◽  
Bruna Corradetti ◽  
Francesca Taraballi ◽  
Monica Sandri ◽  
Jonathan O. Martinez ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Plga Microspheres ◽  
3D Scaffold ◽  
Macrophage Uptake

Curcumin loaded nano graphene oxide reinforced fish scale collagen – a 3D scaffold biomaterial for wound healing applications

RSC Advances ◽  
2015 ◽  
Vol 5 (119) ◽  
pp. 98653-98665 ◽  
Author(s):  
Tapas Mitra ◽  
Piyali Jana Manna ◽  
S. T. K. Raja ◽  
A. Gnanamani ◽  
P. P. Kundu
Keyword(s):  
Tissue Engineering ◽  
Wound Healing ◽  
Graphene Oxide ◽  
Type I Collagen ◽  
Type I ◽  
Fish Scale ◽  
3D Scaffold ◽  
Engineering Research ◽  
Nano Graphene ◽  
Tissue Engineering Research

We prepare a highly stabilized nano graphene oxide functionalized with type I collagen to make a 3D scaffold as a novel platform for better tissue engineering research..

scholarly journals Prospect of Stem Cells in Bone Tissue Engineering: A Review

2016 ◽  
Vol 2016 ◽  
pp. 1-13 ◽  
Author(s):  
Azizeh-Mitra Yousefi ◽  
Paul F. James ◽  
Rosa Akbarzadeh ◽  
Aswati Subramanian ◽  
Conor Flavin ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Stem Cell ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Cell Types ◽  
3D Scaffold ◽  
Stem Cell Source ◽  
Induced Pluripotent

Mesenchymal stem cells (MSCs) have been the subject of many studies in recent years, ranging from basic science that looks into MSCs properties to studies that aim for developing bioengineered tissues and organs. Adult bone marrow-derived mesenchymal stem cells (BM-MSCs) have been the focus of most studies due to the inherent potential of these cells to differentiate into various cell types. Although, the discovery of induced pluripotent stem cells (iPSCs) represents a paradigm shift in our understanding of cellular differentiation. These cells are another attractive stem cell source because of their ability to be reprogramed, allowing the generation of multiple cell types from a single cell. This paper briefly covers various types of stem cell sources that have been used for tissue engineering applications, with a focus on bone regeneration. Then, an overview of some recent studies making use of MSC-seeded 3D scaffold systems for bone tissue engineering has been presented. The emphasis has been placed on the reported scaffold properties that tend to improve MSCs adhesion, proliferation, and osteogenic differentiation outcomes.

scholarly journals Morphofunctional Rearrangement of the Fibrous Structures of the Rat Dermis under the Conditions of Implantation of 3D Scaffold Based on Polyprolactone

2021 ◽  
Vol 11 (3) ◽  
pp. 376-378
Author(s):  
Ekaterina S. Mishina ◽  
Mariya A. Zatolokina ◽  
Lydia M. Ryazaeva ◽  
Viktor S. Pol'skoy
Keyword(s):  
Electron Microscopy ◽  
Tissue Engineering ◽  
Wistar Rats ◽  
White Male ◽  
Cellular Component ◽  
3D Scaffold ◽  
Engineering Structures ◽  
Male Wistar Rats ◽  
Good Biocompatibility ◽  
Scanning Electron

Background: the use of various scaffolds allows us to model the future fibrous framework of the newly formed regenerate, and also serves as a substrate for the settlement of the cellular component. The development of tissue engineering in regenerative medicine demands an understanding of the more specific mechanisms of the formation of the connective framework at the site of the defect. The aim of this research was to study the morphofunctional rearrangement of the fibrous structures of the rat dermis in response to the implantation of a 3D scaffold based on polyprolactone Methods and Results: The experiment was performed on 30 white male Wistar rats. The object of the study was a skin fragment together with an implantable 3D scaffold based on polyprolactone, taken on Days 3, 7 and 14 after implantation. Biomaterial with implantable scaffold was studied using light and scanning electron microscopy. The results of the study indicate that the 3D scaffold based on polyprolactone has good biocompatibility, causing a weak inflammatory reaction, and contributes to the formation of the connective tissue framework by Day 14. Conclusion: The results of the study can be used to develop new scaffolds or modify existing ones, as a "framework" for populating the cellular component and creating tissue-engineering structures.

scholarly journals High Nanodiamond Content-PCL Composite for Tissue Engineering Scaffolds

Nanomaterials ◽  
2020 ◽  
Vol 10 (5) ◽  
pp. 948
Author(s):  
Kate Fox ◽  
Rahul Ratwatte ◽  
Marsilea A. Booth ◽  
Hoai My Tran ◽  
Phong A. Tran
Keyword(s):  
Tissue Engineering ◽  
Surface Roughness ◽  
Tensile Strength ◽  
Composite Material ◽  
Tissue Regeneration ◽  
Composite Films ◽  
Detonation Nanodiamond ◽  
3D Scaffold ◽  
Tissue Engineering Scaffolds ◽  
Osteoblast Adhesion

Multifunctional scaffolds are becoming increasingly important in the field of tissue engineering. In this research, a composite material is developed using polycaprolactone (PCL) and detonation nanodiamond (ND) to take advantage of the unique properties of ND and the biodegradability of PCL polymer. Different ND loading concentrations are investigated, and the physicochemical properties of the composites are characterized. ND-PCL composite films show a higher surface roughness and hydrophilicity than PCL alone, with a slight decrease in tensile strength and a significant increase in degradation. Higher loading of ND also shows a higher osteoblast adhesion than the PCL alone sample. Finally, we show that the ND-PCL composites are successfully extruded to create a 3D scaffold demonstrating their potential as a composite material for tissue regeneration.

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