Water Soluble Non-Aqueous Suspension Concentrates

2009 ◽  
pp. 36-36-15
Author(s):  
NR Pallas ◽  
RJ Riedemann
Keyword(s):  
Aqueous Suspension ◽  
Water Soluble

scholarly journals Helical silver(I)-glutathione biocoordination polymer nanofibres

2013 ◽  
Vol 371 (2000) ◽  
pp. 20120307 ◽  
Author(s):  
Yong Liu ◽  
Chao Li ◽  
Yaling Liu ◽  
Zhiyong Tang
Keyword(s):  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Gold Nanorods ◽  
Negative Refraction ◽  
Aqueous Suspension ◽  
Water Soluble ◽  
Induced Circular Dichroism ◽  
Local Surface ◽  
Helical Structures ◽  
Local Surface Plasmon Resonance

Helical nanofibres of silver(I)-glutathione (Ag-GSH) biocoordination polymer (BCP) are fabricated by introducing dimethyl sulfoxide into the mixture solution of Ag + ions and l -GSH molecules. The prepared BCP nanofibres show hierarchical helical structures, which are constructed via twisting of small fibres. Water-soluble helices could be further cross-linked with Ca 2+ ions to form a well-dispersed aqueous suspension. When gold nanorods are adsorbed onto these helical nanofibres, the unique plasmon-induced circular dichroism characteristic is observed in the region of the local surface plasmon resonance of gold nanorods. This type of chiroptical metamaterials may have promising applications in nonlinear optics, negative refraction and biosensing.

Aqueous suspension of amphiphilic diblock copolymer nanoparticles prepared in situ from a water-soluble poly(sodium acrylate) alkoxyamine macroinitiator

Soft Matter ◽  
2006 ◽  
Vol 2 (3) ◽  
pp. 223 ◽  
Author(s):  
Guillaume Delaittre ◽  
Julien Nicolas ◽  
Catherine Lefay ◽  
Maud Save ◽  
Bernadette Charleux
Keyword(s):  
Diblock Copolymer ◽  
Aqueous Suspension ◽  
Water Soluble ◽  
Sodium Acrylate ◽  
Amphiphilic Diblock Copolymer ◽  
Soluble Poly

Degradation of Tannic Acid Powered by TiO2 Nanoparticles

2012 ◽  
Vol 734 ◽  
pp. 117-126 ◽  
Author(s):  
N. Lakshmi Kruthika ◽  
G. Bhaskar Raju ◽  
S. Prabhakar
Keyword(s):  
Tannic Acid ◽  
Aqueous Suspension ◽  
Water Soluble ◽  
Mineralization Process ◽  
Hydrolysable Tannin ◽  
Diffusion Controlled ◽  
Kinetics Of Degradation ◽  
Paper And Pulp ◽  
Kinetics Of ◽  
Order Rate Equation

The wastewater from the coir, pharmaceutical, leather, paper and pulp industries is contaminated with water-soluble poly phenolic compounds (tannins). Among various tannins, tannic acid is a typical hydrolysable tannin prevalent in wastewater. The degradation of tannic acid using TiO2 nanoparticles as photocatalyst was investigated. The effect of catalyst concentration, pH of aqueous suspension and also electron acceptors such as hydrogen peroxide (H2O2) and ozone (O3) on the degradation of tannic acid was studied. The degradation of tannic acid was found to be more efficient and complete in the presence of UV/TiO2/O3 compared to UV/TiO2/H2O2. The kinetics of degradation was observed to follow first order rate equation which indicates that the mineralization process is diffusion controlled.

scholarly journals Analysis of the chemical composition and properties of the main and side products during the implementation of new technologies for producing ethanol

2020 ◽  
Vol 82 (3) ◽  
pp. 71-77
Author(s):  
N. V. Zueva ◽  
G. V. Agafonov ◽  
I. Y. Lukinova ◽  
A. N. Dolgov
Keyword(s):  
Protein Content ◽  
Crude Protein ◽  
Enzyme Preparation ◽  
Aqueous Suspension ◽  
Feed Additives ◽  
Fiber Content ◽  
Water Soluble ◽  
Cellulolytic Enzyme ◽  
Protein Supplement ◽  
Crude Protein Content

The article studied yeast composition isolated from the separation of the mash, bran separated in the grinding step, as well as a protein supplement obtained by mixing these two products. Crude fat content ranges from 4,7 to 6,2%, crude protein content is 38%, which is 20% lower than in the fodder yeast, but 14% higher than that of the bran. It is also found that the resulting protein product enriched in micro- and macro-elements, as well as readily hydrolyzable and water soluble carbohydrates. crude fiber content is 5,5%, which is almost 2,5 times lower than in the bran. The composition of the feed protein supplement obtained with the introduction at the stage of aqueous suspension of wheat powdery cellulolytic enzyme preparation Viskolaza 150 L and without it. The enzyme preparation was added in the step of preparing aqueous suspensions and wheat powdery dosage of 0,01% by weight of the feedstock. protein feed additives obtained with and without addition of cellulolytic enzyme preparation of high quality crude protein content and protein. Thus, the content of crude protein in the protein with the introduction of an additive in an aqueous suspension of powdery Viskolazy 150 L was 37% whereas 34% without the enzyme preparation. The amount of soluble polysaccharides and the mass fraction of ash were practically at the same level of from 2,4 to 5% and from 5,5 to 7,0%, respectively. fiber content of the protein supplement using Viskolazy 150 L was 4,2-6,1%, which is 2,5 times lower than in the protein supplement obtained without enzyme preparation.

scholarly journals EFFECT OF MICROWAVE IRRADIATION ON ARABINOGALACTAN AND ITS INTERACTION WITH BETULIN DIACETATE

2017 ◽  
pp. 73-79
Author(s):  
Юрий (Yurij) Николаевич (Nikolaevich) Маляр (Malyar) ◽  
Михаил (Mihail) Александрович (Aleksandrovich) Михайленко (Mikhailenko) ◽  
Наталья (Natal'ja) Алексеевна (Alekseevna) Панкрушина (Pankrushina) ◽  
Александр (Aleksandr) Николаевич (Nikolaevich) Михеев (Mikheev) ◽  
Светлана (Svetlana) Алексеевна (Alekseevna) Кузнецова (Kuznetsova) ◽  
...  
Keyword(s):  
Biological Activities ◽  
Aqueous Suspension ◽  
Supramolecular Complex ◽  
Water Soluble ◽  
Conventional Heating ◽  
Complexing Agent ◽  
Solubility In Water ◽  
Betulin Diacetate ◽  
Complex Preparation ◽  
Mw Irradiation

Betulin diacetate (BDA) has a variety of biological activities, but poor solubility in water limits its application. The use of arabinogalactan (AG) as a complexing agent is a promising method for solving the problem of solubilization of drugs. In this work, influence of microwave (MW) irradiation on the properties of AG and BDA and their interaction in the aqueous suspension with formation of a water-soluble supramolecular complex was studied. It is shown that the MW heating of AG under hard conditions can lead to degradation of the biopolymer. The use of MW heating allowed significantly reducing the complex preparation time compared to the conventional synthesis in a water bath. The preliminary mechanical treatment of the mixture of components, leading to the formation of mechanocomposites, inhibited the reaction between the components in the aqueous suspension under MW irradiation. The IR spectroscopy method has shown that a supramolecular complex formed under MW irradiation similar to that formed by conventional heating. BDA-AG complex was isolated from a MW heated solution as a thin film, which may be a promising material for pharmaceutical applications.

Floating Alginate Beads as Carriers for Self-Emulsifying System Containing Tetrahydrocurcumin

2012 ◽  
Vol 506 ◽  
pp. 517-520 ◽  
Author(s):  
S. Sriraksa ◽  
N. Sermkaew ◽  
S. Setthacheewakul ◽  
R. Wiwattanapatapee
Keyword(s):  
Oral Delivery ◽  
Aqueous Suspension ◽  
Aqueous Solubility ◽  
Gastric Fluid ◽  
Alginate Beads ◽  
Water Soluble ◽  
Simulated Gastric Fluid ◽  
Pore Former ◽  
Gastric Residence Time

Tetrahydrocurcumin (THC), one of the curcumin metabolites, exhibits pharmacological activities such as antioxidant, anti-inflammatory and anti-carcinogenic properties. However, the pharmacological effect of THC is limited due to its low aqueous solubility. Floating alginate beads containing self-emulsifying drug delivery system (SEDDS) of THC were developed to increase drug solubility and prolong gastric residence time. Use of different weight proportions of sodium alginate (Na-alg.), calcium chloride (CaCl2) and water soluble pore former (Polyvinylalcohol-polyethylene glycol copolymer; Kollicoat® IR) in bead formulations had different effects on the floating abilities and in vitro rate of THC release. The release profile of the optimized THC-SEDDS floating alginate beads (D3) indicated a significant increase in the dissolution rate of THC and provided a controlled release of THC over an 8 h period in a simulated gastric fluid. The release of about 80% of THC from the optimized beads as an o/w microemulsion with a particle size of less than 50 nm, compared to only 30 % by an aqueous suspension from the unformulated THC could be considerable greater absorbed. The self-emulsifying floating alginate beads may provide a useful solid dosage form for oral delivery of THC and other hydrophobic compounds.

scholarly journals Sustained absorption of delamanid from lipid-based formulations as a path to reduced frequency of administration

2020 ◽  
Author(s):  
Gisela Ramirez ◽  
Anna C. Pham ◽  
Andrew J. Clulow ◽  
Malinda Salim ◽  
Adrian Hawley ◽  
...  
Keyword(s):  
Self Assembly ◽  
Aqueous Suspension ◽  
Aqueous Media ◽  
Milk Powder ◽  
Water Soluble ◽  
Selachyl Alcohol ◽  
Self Assembling ◽  
Suspension Formulation ◽  
Poorly Water Soluble ◽  
Reconstituted Milk

Abstract Delamanid is a poorly water-soluble drug currently being used for the treatment of tuberculosis. The high frequency of dosing leads to poor adherence for patients who live in lower economic and nomadic populations. Non-digestible self-assembling lipids as a formulation approach for poorly water-soluble drugs have previously been shown to extend the window of absorption through gastric retention. We hypothesise that this approach could lead to the reduction of dosing frequency for delamanid and thereby has potential to improve adherence. Formulations of delamanid were prepared in selachyl alcohol and phytantriol as non-digestible self-assembling lipid vehicles, and their behaviour was compared with reconstituted milk powder, as a digestible lipid-based formulation, and an aqueous suspension. The self-assembly of selachyl alcohol and phytantriol in aqueous media in the presence of delamanid was studied using small angle X-ray scattering and produced the inverse hexagonal (H2) and inverse bicontinuous cubic (V2) liquid crystal structures, respectively. The times at which maximum delamanid levels in plasma were observed (Tmax) after oral administration of the phytantriol, selachyl alcohol and reconstituted milk powder formulations of delamanid to rats were 27 ± 3, 20 ± 4 and 6.5 ± 1.0 h, respectively, compared with the aqueous suspension formulation with a Tmax of 3.4 ± 1 h, which confirms the hypothesis of an extended duration of absorption after administration in non-digestible self-assembling lipids. The digestion products of the triglycerides in the milk formulation increased the solubilisation of delamanid in the gastrointestinal tract, leading to an increase in exposure compared with the aqueous suspension formulation but did not significantly extend Tmax. Overall, the non-digestible nanostructured lipid formulations extended the duration of absorption of delamanid well beyond that from milk or suspension formulations.

A Resorcinol-Formaldehyde Resin as an Embedding Material for Electron Microscopy of Membranes

1969 ◽  
Vol 27 ◽  
pp. 328-329 ◽  
Author(s):  
J. G. Robertson ◽  
D. F. Parsons
Keyword(s):  
Electron Microscopy ◽  
Osmium Tetroxide ◽  
Neutral Lipids ◽  
Lipid Extraction ◽  
Water Soluble ◽  
Formaldehyde Resin ◽  
Electron Microscope Autoradiography ◽  
Resorcinol Formaldehyde ◽  
Major Disadvantage ◽  
Cell Organization

The extraction of lipids from tissues during fixation and embedding for electron microscopy is widely recognized as a source of possible artifact, especially at the membrane level of cell organization. Lipid extraction is also a major disadvantage in electron microscope autoradiography of radioactive lipids, as in studies of the uptake of radioactive fatty acids by intestinal slices. Retention of lipids by fixation with osmium tetroxide is generally limited to glycolipids, phospholipids and highly unsaturated neutral lipids. Saturated neutral lipids and sterols tend to be easily extracted by organic dehydrating reagents prior to embedding. Retention of the more saturated lipids in embedded tissue might be achieved by developing new cross-linking reagents, by the use of highly water soluble embedding materials or by working at very low temperatures.

Ferritin Labeled Antibody Staining of Thin Sections

1969 ◽  
Vol 27 ◽  
pp. 420-421
Author(s):  
J. D. McLean ◽  
S. J. Singer
Keyword(s):  
Biological Material ◽  
Water Soluble ◽  
Thin Sections ◽  
Antibody Staining ◽  
Thin Sectioning ◽  
Ultrathin Sections

The successful application of ferritin labeled antibodies (F-A) to ultrathin sections of biological material has been hampered by two main difficulties. Firstly the normally used procedures for the preparation of material for thin sectioning often result in a loss of antigenicity. Secondly the polymers employed for embedding may non-specifically absorb the F-A. Our earlier use of cross-linked polyampholytes as embedding media partially overcame these problems. However the water-soluble monomers used for this method still extract many lipids from the material.

Sign in / Sign up

Export Citation Format

Share Document