Effects of Argon Laser Light, Alternate Source Light, and Cyanoacrylate Fuming on DNA Typing of Human Bloodstains

1993 ◽  
Vol 38 (1) ◽  
pp. 13391J ◽  
Author(s):  
Ed Shipp ◽  
Renee Roelofs ◽  
Enrico Togneri ◽  
Raymond Wright ◽  
David Atkinson ◽  
...  
Author(s):  
Burton B. Silver ◽  
Theodore Lawwill

Dutch-belted 1 to 2.5 kg anesthetized rabbits were exposed to either xenon or argon laser light administered in a broad band, designed to cover large areas of the retina. For laser exposure, the pupil was dilated with atropine sulfate 1% and pheny lephrine 10%. All of the laser generated power was within a band centered at 5145.0 Anstroms. Established threshold for 4 hour exposures to laser irradiation are in the order of 25-35 microwatts/cm2. Animals examined for ultrastructural changes received 4 hour threshold doses. These animals exhibited ERG, opthalmascopic, and histological changes consistent with threshold damage.One month following exposure the rabbits were killed with pentobarbitol. The eyes were immediately enucleated and dissected while bathed in 3% phosphate buffered gluteraldehyde.


1985 ◽  
Vol 5 (3) ◽  
pp. 249-251
Author(s):  
Kenichi Ido ◽  
Hitoshi Takahashi ◽  
Tomohiko Terada ◽  
Hiroyoshi Arai ◽  
Tetsuo Kasano ◽  
...  

2003 ◽  
Author(s):  
Z.F. Gourgouliatos ◽  
S. Ghaffari ◽  
A.J. Welch ◽  
K.R. Diller ◽  
R.C. Straight

1987 ◽  
Vol 67 (6) ◽  
pp. 889-894 ◽  
Author(s):  
Stephen K. Powers ◽  
William C. Beckman ◽  
J. Tony Brown ◽  
Linda C. Kolpack

✓ The effect of interstitial laser photochemotherapy with the mitochondrial-specific intravital dye rhodamine-123 (Rh-123) was studied using a malignant rat glioma model system (RT2). Tumors were transplanted subcutaneously into the flank of athymic mice and into the cerebrum of adult rats. The Rh-123 photosensitization was produced by direct intratumoral injection of Rh-123 into the mouse RT2 flank tumors and by intravenous Rh-123 administration to adult rats with implanted RT2 intracerebral tumors. Intratumoral irradiation with 150 mW of argon laser light for an exposure time of 15 minutes was performed using a conical sapphire-tipped quartz optical fiber. Control groups of animals received either no treatment, Rh-123 injections, or administration of 150 mW of argon laser light for 15 minutes. Both flank and intracerebral tumors showed progressive diminution in size after treatment with Rh-123 photochemotherapy. There was no evidence of tumor recurrence in 60% of Rh-123 photochemotherapy-treated tumors. Recurrences in tumors treated with Rh-123 photochemotherapy usually appeared at the periphery of the original tumor at 10 days after treatment. Histologically, photochemotherapy-treated intracerebral tumors showed progressive shrinkage with increasing tumor necrosis over time. The finding of residual or recurrent tumor at the periphery of the original tumor mass suggests that the lack of penetration of the blue-green (argon) light was responsible for preventing complete tumor ablation. Our results suggest that Rh-123 photochemotherapy can destroy malignant gliomas in vivo; however, the poor penetrability of the photoactivating blue-green light may limit the effectiveness of this treatment for large or extensively invasive tumors.


1992 ◽  
Vol 7 (1-4) ◽  
pp. 63-71 ◽  
Author(s):  
Zafirios F. Gourgouliatos ◽  
Ashley J. Welch ◽  
Kenneth R. Diller

1987 ◽  
Vol 2 (4) ◽  
pp. 255-260 ◽  
Author(s):  
J. G. Wolbers ◽  
W. Kamphorst ◽  
H. J. C. M. Sterenborg ◽  
M. J. C. Van Gemert ◽  
W. Hogervorst

Sign in / Sign up

Export Citation Format

Share Document