scholarly journals Cytotoxicity and Acute Gastrointestinal Toxicity of Bacterial Cellulose-Poly (acrylamide-sodium acrylate) Hydrogel: A Carrier for Oral Drug Delivery

2016 ◽  
Vol 22 (4) ◽  
pp. 291-295 ◽  
Author(s):  
Manisha Pandey ◽  
Hira Choudhury ◽  
Mohd Cairul Iqbal Mohd Amin
Keyword(s):  
Drug Delivery ◽  
Bacterial Cellulose ◽  
Oral Drug Delivery ◽  
Gastrointestinal Toxicity ◽  
Oral Drug ◽  
Sodium Acrylate ◽  
Poly Acrylamide

Preparation, characterization and in-vitro evaluation of bacterial cellulose matrices for oral drug delivery

Cellulose ◽  
2017 ◽  
Vol 24 (11) ◽  
pp. 5041-5052 ◽  
Author(s):  
Munair Badshah ◽  
Hanif Ullah ◽  
Shujaat Ali Khan ◽  
Joong Kon Park ◽  
Taous Khan
Keyword(s):  
Drug Delivery ◽  
Bacterial Cellulose ◽  
Oral Drug Delivery ◽  
Oral Drug ◽  
In Vitro Evaluation

scholarly journals Rapid Synthesis of Superabsorbent Smart-Swelling Bacterial Cellulose/Acrylamide-Based Hydrogels for Drug Delivery

2013 ◽  
Vol 2013 ◽  
pp. 1-10 ◽  
Author(s):  
Manisha Pandey ◽  
Mohd Cairul Iqbal Mohd Amin ◽  
Naveed Ahmad ◽  
Muhammad Mustafa Abeer
Keyword(s):  
Drug Delivery ◽  
Bacterial Cellulose ◽  
Oral Drug Delivery ◽  
Drug Loading ◽  
Solvent System ◽  
Physicochemical Characteristics ◽  
Oral Drug ◽  
X Ray Diffraction ◽  
Spectroscopy Analysis ◽  
Drug Release Profile

This study evaluated the effect of solubilized and dispersed bacterial cellulose (BC) on the physicochemical characteristics and drug release profile of hydrogels synthesized using biopolymers. Superabsorbent hydrogels were synthesized by graft polymerization of acrylamide on BC solubilized in an NaOH/urea solvent system and on dispersed BC by usingN,N′-methylenebisacrylamide as a crosslinker under microwave irradiation. Fourier transform infrared spectroscopy analysis of the resulting hydrogels confirmed the grafting, and an X-ray diffraction pattern showed a decrease in the crystallinity of BC after the grafting process. The hydrogels exhibited pH and ionic responsive swelling behavior, with hydrogels prepared using solubilized BC (SH) having higher swelling ratios. Furthermore, compared to the hydrogels synthesized using dispersed BC, the hydrogels synthesized using solubilized BC showed higher porosity, drug loading efficiency, and release. These results suggest the superiority of the hydrogels prepared using solubilized BC and that they should be explored further for oral drug delivery.

Controlled release of Doxycycline from gum acacia/poly(sodium acrylate) microparticles for oral drug delivery

2017 ◽  
Vol 104 ◽  
pp. 1064-1071 ◽  
Author(s):  
S.K. Bajpai ◽  
Mamta Jadaun ◽  
M. Bajpai ◽  
Pooja Jyotishi ◽  
Farhan Ferooz Shah ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Controlled Release ◽  
Oral Drug Delivery ◽  
Oral Drug ◽  
Sodium Acrylate ◽  
Gum Acacia

Fabrication, characterization and evaluation of bacterial cellulose-based capsule shells for oral drug delivery

Cellulose ◽  
2017 ◽  
Vol 24 (3) ◽  
pp. 1445-1454 ◽  
Author(s):  
Hanif Ullah ◽  
Munair Badshah ◽  
Ermei Mäkilä ◽  
Jarno Salonen ◽  
Mohammad-Ali Shahbazi ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Bacterial Cellulose ◽  
Oral Drug Delivery ◽  
Oral Drug

Applications of Ion Exchange Resin in Oral Drug Delivery Systems

2017 ◽  
Vol 7 (03) ◽  
Author(s):  
Kathpalia Harsha ◽  
Das Sukanya
Keyword(s):  
Drug Delivery ◽  
Ion Exchange ◽  
Drug Delivery Systems ◽  
Oral Drug Delivery ◽  
Physical Stability ◽  
Delivery Systems ◽  
Oral Drug ◽  
Ion Exchange Resins ◽  
Exchange Resins ◽  
Oral Drug Delivery Systems

Ion Exchange Resins (IER) are insoluble polymers having styrene divinylbenzene copolymer backbone that contain acidic or basic functional groups and have the ability to exchange counter ions with the surrounding aqueous solutions. From the past many years they have been widely used for purification and softening of water and in chromatographic columns, however recently their use in pharmaceutical industry has gained considerable importance. Due to the physical stability and inert nature of the resins, they can be used as a versatile vehicle to design several modified release dosage forms The ionizable drug is complexed with the resin owing to the property of ion exchange. This resin complex dissociatesin vivo to release the drug. Based on the dissociation strength of the drug from the drug resin complex, various release patterns can be achieved. Many formulation glitches can be circumvented using ion exchange resins such as bitter taste and deliquescence. These resins also aid in enhancing disintegrationand stability of formulation. This review focuses on different types of ion exchange resins, their preparation methods, chemistry, properties, incompatibilities and their application in various oral drug delivery systems as well as highlighting their use as therapeutic agents.

Implication of Nanofibers in Oral Drug Delivery

2015 ◽  
Vol 21 (15) ◽  
pp. 2021-2036 ◽  
Author(s):  
Himani Kapahi ◽  
Nikhat Khan ◽  
Ankur Bhardwaj ◽  
Neeraj Mishra
Keyword(s):  
Drug Delivery ◽  
Oral Drug Delivery ◽  
Oral Drug

Fat-Soluble Vitamins Release Based on Clinoptilolite Zeolite as an Oral Drug Delivery System

2012 ◽  
Vol 9 (2) ◽  
pp. 213-217 ◽  
Author(s):  
Mehdi Rahimi ◽  
Hamid Mobedi ◽  
Aliasghar Behnamghader ◽  
Alireza Nateghi Baygi ◽  
Houri Mivehchi ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Oral Drug Delivery ◽  
Oral Drug ◽  
Oral Drug Delivery System ◽  
Clinoptilolite Zeolite ◽  
Fat Soluble Vitamins
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