scholarly journals Engineered nanomaterials and human health: Part 1. Preparation, functionalization and charact-erization (IUPAC Technical Report)

2018 ◽  
Vol 40 (4) ◽  
pp. 34-34
Keyword(s):  
Human Health ◽  
Engineered Nanomaterials ◽  
Technical Report

scholarly journals Engineered nanomaterials and human health: Part 2. Applications and nanotoxicology (IUPAC Technical Report)

2018 ◽  
Vol 90 (8) ◽  
pp. 1325-1356 ◽  
Author(s):  
Vladimir Gubala ◽  
Linda J. Johnston ◽  
Harald F. Krug ◽  
Colin J. Moore ◽  
Christopher K. Ober ◽  
...  
Keyword(s):  
Human Health ◽  
Careful Consideration ◽  
Consumer Products ◽  
Engineered Nanomaterials ◽  
Risk Regulation ◽  
Biological Targets ◽  
Nanosized Materials ◽  
Size Dependent ◽  
Expert Opinions ◽  
Technical Report

AbstractResearch on engineered nanomaterials (ENM) has progressed rapidly from the very early stages of studying their unique, size-dependent physicochemical properties and commercial exploration to the development of products that influence our everyday lives. We have previously reviewed various methods for synthesis, surface functionalization, and analytical characterization of ENM in a publication titled ‘Engineered Nanomaterials: Preparation, Functionalization and Characterization’. In this second, inter-linked document, we first provide an overview of important applications of ENM in products relevant to human healthcare and consumer goods, such as food, textiles, and cosmetics. We then highlight the challenges for the design and development of new ENM for bio-applications, particularly in the rapidly developing nanomedicine sector. The second part of this document is dedicated to nanotoxicology studies of ENM in consumer products. We describe the various biological targets where toxicity may occur, summarize the four nanotoxicology principles, and discuss the need for careful consideration of the biodistribution, degradation, and elimination routes of nanosized materials before they can be safely used. Finally, we review expert opinions on the risk, regulation, and ethical aspects of using engineered nanomaterials in applications that may have direct or indirect impact on human health or our environment.

Nano-QSAR modeling for ecosafe design of heterogeneous TiO2-based nano-photocatalysts

2018 ◽  
Vol 5 (5) ◽  
pp. 1150-1160 ◽  
Author(s):  
Alicja Mikolajczyk ◽  
Agnieszka Gajewicz ◽  
Ewa Mulkiewicz ◽  
Bakhtiyor Rasulev ◽  
Martyna Marchelek ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Human Health ◽  
Environmental Risk ◽  
Environmental Risk Assessment ◽  
Engineered Nanomaterials ◽  
Qsar Modeling ◽  
High Interest

The human health and environmental risk assessment of engineered nanomaterials (NPs) is nowadays of high interest.

scholarly journals Engineered nanomaterials and human health: Part 1. Preparation, functionalization and characterization (IUPAC Technical Report)

2018 ◽  
Vol 90 (8) ◽  
pp. 1283-1324 ◽  
Author(s):  
Vladimir Gubala ◽  
Linda J. Johnston ◽  
Ziwei Liu ◽  
Harald Krug ◽  
Colin J. Moore ◽  
...  
Keyword(s):  
Close Contact ◽  
Consumer Products ◽  
Engineered Nanomaterials ◽  
Diverse Range ◽  
Size Dependent ◽  
Current State ◽  
Technical Report ◽  
Potential Benefits ◽  
To Come ◽  
Number Of Publications

Abstract Nanotechnology is a rapidly evolving field, as evidenced by the large number of publications on the synthesis, characterization, and biological/environmental effects of new nano-sized materials. The unique, size-dependent properties of nanomaterials have been exploited in a diverse range of applications and in many examples of nano-enabled consumer products. In this account we focus on Engineered Nanomaterials (ENM), a class of deliberately designed and constructed nano-sized materials. Due to the large volume of publications, we separated the preparation and characterisation of ENM from applications and toxicity into two interconnected documents. Part 1 summarizes nanomaterial terminology and provides an overview of the best practices for their preparation, surface functionalization, and analytical characterization. Part 2 (this issue, Pure Appl. Chem. 2018; 90(8): 1325–1356) focuses on ENM that are used in products that are expected to come in close contact with consumers. It reviews nanomaterials used in therapeutics, diagnostics, and consumer goods and summarizes current nanotoxicology challenges and the current state of nanomaterial regulation, providing insight on the growing public debate on whether the environmental and social costs of nanotechnology outweigh its potential benefits.

Interplay between engineered nanomaterials and microbiota

2020 ◽  
Author(s):  
Yirong Zhang ◽  
Monika Mortimer ◽  
Liang-Hong Guo
Keyword(s):  
Human Health ◽  
Crucial Role ◽  
Engineered Nanomaterials ◽  
Health And Disease

The growing evidence of the microbiome’s crucial role in human health and disease has prompted research on understanding the impacts of engineered nanomaterials (ENMs) on commensal microorganisms. Accordingly, the number...

scholarly journals Susceptibility Factors in Chronic Lung Inflammatory Responses to Engineered Nanomaterials

2020 ◽  
Vol 21 (19) ◽  
pp. 7310
Author(s):  
Dorothy J. You ◽  
James C. Bonner
Keyword(s):  
Human Health ◽  
Inflammatory Responses ◽  
Inhalation Exposure ◽  
Adaptive Immune Response ◽  
Engineered Nanomaterials ◽  
Pulmonary Exposure ◽  
Adaptive Immune ◽  
Susceptibility Factors ◽  
Genes Encoding ◽  
Increasing Demand

Engineered nanomaterials (ENMs) are products of the emerging nanotechnology industry and many different types of ENMs have been shown to cause chronic inflammation in the lungs of rodents after inhalation exposure, suggesting a risk to human health. Due to the increasing demand and use of ENMs in a variety of products, a careful evaluation of the risks to human health is urgently needed. An assessment of the immunotoxicity of ENMs should consider susceptibility factors including sex, pre-existing diseases, deficiency of specific genes encoding proteins involved in the innate or adaptive immune response, and co-exposures to other chemicals. This review will address evidence from experimental animal models that highlights some important issues of susceptibility to chronic lung inflammation and systemic immune dysfunction after pulmonary exposure to ENMs.

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