Effects of Acute, Heavy-Resistance Exercise on Urinary Peptide Hormone Excretion in Humans

Author(s):  
Elio F. De Palo ◽  
Rosalba Gatti ◽  
Federica Lancerin ◽  
Carlo B. De Palo ◽  
Enrico Cappellin ◽  
...  
Antioxidants ◽  
2019 ◽  
Vol 8 (12) ◽  
pp. 587
Author(s):  
Heidar Mohammadjafari ◽  
Hamid Arazi ◽  
Nematollah Nemati ◽  
Tahereh Bagherpoor ◽  
Katsuhiko Suzuki

The aim of this study was to examine the influence of peptide hormone use on oxidative stress and antioxidant responses to a single session of resistance exercise in male bodybuilders. Forty-five male bodybuilders were divided into three groups: bodybuilders using growth hormone for at least 1 year (i.e., 3 to 4 times in the year) (GH-user, n = 15), bodybuilders using insulin-like growth factor-1 for at least 1 year (i.e., 3 to 4 times in the year) (IGF-1-user, n = 15), and peptide hormone-free bodybuilders (Non-user, n = 15). The heavy resistance exercise protocol consisted of five sets with 80% of one repetition maximum for six exercises. Blood samples were obtained pre and post heavy resistance exercise (HRE) in order to evaluate changes in oxidative stress (8-hydroxy-2-deoxyguanosine (8-OHdG), malondialdehyde (MDA), and nitric oxide (NO)) and antioxidant biomarkers (glutathione peroxidase (GPx), catalase (CAT) and glutamate (GLU)) level. All the experimental groups showed increases in MDA (p = 0.038), NO (p = 0.028), GPx (p = 0.012), and GLU (p = 0.003) concentrations after resistance exercise. For 8-OHdG, the Non-user and IGF-1-user groups indicated increases at post-exercise (p = 0.001), without any significant changes in the GH-user group (p = 0.87). In addition, the changes in serum GPx and GLU levels were greater for the GH-user group than the Non-user and IGF-1-user groups (p = 0.001). In conclusion, HRE induced significant increases in 8-OHdG (except to GH-user group), MDA, NO, GPx, and GLU levels with greater changes in GPx and GLU for the GH-user group.


1993 ◽  
Author(s):  
William J. Kraemer ◽  
Steven J. Fleck ◽  
Joseph E. Dziados ◽  
Everett A. Harman ◽  
Louis J. Marchitelli

2000 ◽  
Vol 25 (1) ◽  
pp. 68-78 ◽  
Author(s):  
Craig S. Ballantyne ◽  
Stuart M. Phillips ◽  
Jay R. Macdonald ◽  
Mark A. Tarnopolsky ◽  
J. Duncan Macdougall

We examined the effects of androstenedione supplementation on the hormonal profile of 10 males and its interaction with resistance exercise. Baseline testosterone, luteinizing hormone, estradiol, and androstenedione concentrations were established by venous sampling at 3 hr intervals over 24 hr. Subjects ingested 200 mg of androstenedione daily for 2 days, with second and third day blood samples. Two weeks later, they ingested androstenedione or a placebo for 2 days, in a double-blind, cross-over design. On day 2, they performed heavy resistance exercise with blood sampled before, after, and 90 min post. The supplement elevated plasma androstenedione 2-3-fold and luteinizing hormone ∼70% but did not alter testosterone concentration. Exercise elevated testosterone, with no difference between conditions. Exercise in the supplemented condition significantly elevated plasma estradiol by ∼83% for 90 min. Androstenedione supplementation, thus, is unlikely to provide male athletes with any anabolic benefit and, with heavy resistance exercise, elevates estrogen. Key Words: testosterone, luteinizing hormone, estradiol, fluid shifts, resistance exercise


2017 ◽  
Vol 118 (2) ◽  
pp. 313-320 ◽  
Author(s):  
Kestutis Bunevicius ◽  
Albinas Grunovas ◽  
Tomas Venckunas ◽  
Kristina Poderiene ◽  
Eugenijus Trinkunas ◽  
...  

2000 ◽  
Vol 14 (3) ◽  
pp. 344-349 ◽  
Author(s):  
JILL A. BUSH ◽  
KEIICHIRO DOHI ◽  
ANDREA M. MASTRO ◽  
JEFF S. VOLEK ◽  
J. MICHAEL LYNCH ◽  
...  

1990 ◽  
Vol 69 (2) ◽  
pp. 434-437 ◽  
Author(s):  
K. E. Yarasheski ◽  
P. W. Lemon ◽  
J. Gilloteaux

The purpose of this investigation was to determine whether heavy-resistance exercise training alters the skeletal muscle fiber composition of young rats. Ten male Long Evans rats (3 wk old) were trained to lift progressively heavier weights, which were secured to the rats' tails, while they ascended a 40-cm 90 degree mesh incline 20 times/day 5 days/wk for a food reward. After 8 wk of training, they lifted 406 +/- 19 (SD) g in addition to their body weight (261 +/- 9 g). Compared with 10 sedentary pair-fed rats, no hypertrophy of forelimb muscles (biceps brachii and brachialis) was observed, but rectus femoris wet and dry weights were greater (P less than 0.01) in the trained group. In the deep region of the rectus femoris, type I fiber area was similar between groups, but the trained rats had both a lower (P less than 0.05) percentage of type I fibers and a smaller (P less than 0.05) portion of the total area occupied by type I fibers. The percentage of type IIb fibers in the deep region of the rectus femoris was also similar between groups, but the portion of the deep area composed of type IIb fibers was greater (P less than 0.05) in the trained rats. In the superficial region of the rectus femoris, the trained rats' type IIb fibers were larger (P less than 0.01) and occupied a greater (P less than 0.05) portion of the superficial muscle area.(ABSTRACT TRUNCATED AT 250 WORDS)


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