Comparison of commercial iron oxide-based MRI contrast agents with synthesized high-performance MPI tracers

2013 ◽  
Vol 58 (6) ◽  
Author(s):  
Kerstin Lüdtke-Buzug ◽  
Julian Haegele ◽  
Sven Biederer ◽  
Timo F. Sattel ◽  
Marlitt Erbe ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Contrast Agents ◽  
High Performance ◽  
Mri Contrast Agents ◽  
Mri Contrast ◽  
Commercial Iron

One-Step Synthesis of Single-Stranded DNA-Bridged Iron Oxide Supraparticles as MRI Contrast Agents

Nano Letters ◽  
2021 ◽  
Vol 21 (7) ◽  
pp. 2793-2799
Author(s):  
Jingfang Zhang ◽  
Zhenghan Di ◽  
Husheng Yan ◽  
Yuliang Zhao ◽  
Lele Li
Keyword(s):  
Iron Oxide ◽  
Contrast Agents ◽  
Mri Contrast Agents ◽  
Single Stranded Dna ◽  
Mri Contrast ◽  
One Step

Cooperative Organization in Iron Oxide Multi-Core Nanoparticles Potentiates Their Efficiency as Heating Mediators and MRI Contrast Agents

ACS Nano ◽  
2012 ◽  
Vol 6 (12) ◽  
pp. 10935-10949 ◽  
Author(s):  
Lénaic Lartigue ◽  
Pierre Hugounenq ◽  
Damien Alloyeau ◽  
Sarah P. Clarke ◽  
Michael Lévy ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Contrast Agents ◽  
Mri Contrast Agents ◽  
Mri Contrast ◽  
Cooperative Organization ◽  
Core Nanoparticles

Synthesis of Iron Oxide Nanoparticles Used as MRI Contrast Agents: A Parametric Study

1999 ◽  
Vol 212 (2) ◽  
pp. 474-482 ◽  
Author(s):  
Lucia Babes ◽  
Benoı̂t Denizot ◽  
Gisèle Tanguy ◽  
Jean Jacques Le Jeune ◽  
Pierre Jallet
Keyword(s):  
Iron Oxide ◽  
Contrast Agents ◽  
Iron Oxide Nanoparticles ◽  
Parametric Study ◽  
Mri Contrast Agents ◽  
Oxide Nanoparticles ◽  
Mri Contrast

Sequential growth of CaF2:Yb,Er@CaF2:Gd nanoparticles for efficient magnetic resonance angiography and tumor diagnosis

2017 ◽  
Vol 5 (12) ◽  
pp. 2403-2415 ◽  
Author(s):  
Kun Liu ◽  
Xu Yan ◽  
Yun-Jun Xu ◽  
Liang Dong ◽  
Li-Na Hao ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Magnetic Resonance Angiography ◽  
Contrast Agents ◽  
High Performance ◽  
Mri Contrast Agents ◽  
Resonance Imaging ◽  
Mri Contrast ◽  
Significant Challenge ◽  
Magnetic Resonance Imaging Mri

It is a significant challenge to develop nanoscale magnetic resonance imaging (MRI) contrast agents with high performance of relaxation.

The Gadonanotubes as High-Performance MRI Contrast Agents: The Unappreciated Role of the Carbon Nanotube Component at Low Magnetic Fields

2017 ◽  
Vol 6 (6) ◽  
pp. M3173-M3180 ◽  
Author(s):  
Sakineh E. Moghaddam ◽  
Richa Sethi ◽  
Farzaneh Shayeganfar ◽  
Robert G. Bryant ◽  
Lon J. Wilson
Keyword(s):  
Carbon Nanotube ◽  
Magnetic Fields ◽  
Contrast Agents ◽  
High Performance ◽  
Mri Contrast Agents ◽  
Mri Contrast

scholarly journals Digital Simulation Assessments of the Sensitivity of Quantitative MRI for Detection of an Iron Oxide Nanoparticle Brain MRI Contrast Agent

2021 ◽  
Author(s):  
Joong Kim ◽  
Wen-Tung Wang ◽  
Andrew Knutsen ◽  
David Brody
Keyword(s):  
Iron Oxide ◽  
Contrast Agent ◽  
Contrast Agents ◽  
Digital Simulation ◽  
Brain Mri ◽  
Mri Contrast Agents ◽  
Mri Contrast Agent ◽  
Simulation Approach ◽  
Mri Contrast ◽  
Mr Relaxation

Abstract There have been substantial efforts to develop targeted exogenous MRI contrast agents to assess specific brain pathologies. In parallel with other efforts, it is important to assess the sensitivity of candidate MRI methods for detection of contrast agents. Here, we propose a digital simulation approach, which includes MR relaxation (R1 and R2) mapping and image co-registration. We simulated the effects of 3 nm iron oxide nanoparticles (IONPs) as a model contrast agent. Two independent relaxation maps acquired from the brain of the same subject were co-registered. The baseline subtraction between the two relaxation maps showed good agreement, demonstrating the high reproducibility of the method. Next, the second relaxation map was digitally altered (“seeded”) to simulate additional MR relaxation values corresponding to several concentrations of 3 nm IONPs in various locations. The maps of absolute differences between the first relaxation map and the digitally altered second relaxation maps were assessed for conspicuity. Results based on living mouse and human brains scanned at 9.4 T and 3.0 T respectively both indicated reliable conspicuity for signal equivalent to 0.06 mM IONP or higher. Overall, the digital simulation approach is a useful method to improve the development of MRI contrast agents and accompanying MRI methodologies.

scholarly journals CARS microscopy for the visualization of micrometer-sized iron oxide MRI contrast agents in living cells

2011 ◽  
Vol 2 (9) ◽  
pp. 2470 ◽  
Author(s):  
Gianluca Rago ◽  
Carolin M. Langer ◽  
Christian Brackman ◽  
James P.R. Day ◽  
Katrin F. Domke ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Contrast Agents ◽  
Living Cells ◽  
Mri Contrast Agents ◽  
Mri Contrast ◽  
Cars Microscopy
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