Japanese encephalitis vaccines – needs, flaws and achievements

2008 ◽  
Vol 389 (5) ◽  
Author(s):  
Erich Tauber ◽  
Shailesh Dewasthaly

Abstract Japanese encephalitis causes serious health problems in countries in Southeast Asia, where the causative virus is endemic. Whereas most adults living in this region have acquired immunity, children are at high risk of infection. Childhood mass immunization programs with first-generation mouse brain-derived vaccines efficiently reduced Japanese encephalitis incidence in affected countries, but immunization recommendations have mostly been abolished in Japan owing to the occurrence of severe side effects. Thus, there is a pressing need for safer vaccines to keep the disease under control. The safety profile of the current vaccines, together with the relatively low incidence, makes the risk/benefit ratio unfavorable for immunization of travelers to Southeast Asia, despite the high mortality once the clinical disease has developed. As Asian countries become increasingly popular travel destinations, the availability of well-tolerated vaccines would likely shift the ratio towards immunization. Currently, there is one second-generation inactivated cell-culture-grown vaccine in late-stage clinical development that is approaching licensing in developed countries.

2020 ◽  
Vol 11 (3) ◽  
pp. 17-25
Author(s):  
Otabek Alimardonov ◽  

Today, Malaysia is one of the most developed countries in Southeast Asia and a close partner of Uzbekistan in the region. Taking into account the peculiarities of the development and achievements of the countries of Southeast Asia, the Government of Uzbekistan from the first years of independence has paid special attention to the establishment and development of cooperation with Malaysia


Author(s):  
Justin Paul ◽  
Archana Shrivastava

Purpose – The purpose of this paper is to compare entrepreneurial attributes of MBA students, the next generation business people, from two important Asian countries, India from South Asia and Japan from East Asia (India, being an emerging country and Japan, a developed country). Design/methodology/approach – Survey responses from MBA students in India and Japan were measured on an entrepreneurial personality index. Bateman and Crant’s scale consisting of 17 traits is used to identify if entrepreneurial traits are a learned cultural behaviour or intrinsic personality factors. Findings – Although the findings indicate that India has benefitted from entrepreneurship in the information technology and information technology-enabled service ventures during the past two decades, the country still has a long way to go when compared to developed countries like Japan, where entrepreneurship is widespread. Research limitations/implications – The results are based on a single survey, using cross-sectional data. Originality/value – The level of entrepreneurship differs considerably across countries and periods. The authors put forward a theoretical framework to denote the linkage between entrepreneurial attitude, pro-active personality and culture, besides highlighting the three pillars of entrepreneurship.


2021 ◽  
pp. 951-965
Author(s):  
Yana Vadimovna Mishchenko

The article discusses the main results of two major international summits held in October-November 2021, the key topics of which were the issues of the global fight against climate change and environmental protection. The decisions taken at these conferences, with the broad participation of world leaders, reflect the fundamental trends of the global environmental agenda. Within the framework of this agenda, Japan and the countries of Southeast Asia are building their modern energy and environmental cooperation. In this context, the article examines the main urgent tasks of energy-environmental interaction and sustainable development of Japan and the states of Southeast Asia. These countries are located in the Asia-Pacific region, which remains until now the main emitter of greenhouse gases in the world. However, the indicators of environmental pollution by Japan and the Southeast Asian countries are relatively not so high, compared to some other states in the region and the world. The article discusses the most relevant and significant examples of bilateral and multilateral cooperation between these countries in areas related to curbing global warming and climate protection. It has been revealed that with all the efforts made, since the 1990s, the indicators of reducing harmful emissions into the atmosphere in Japan remain modest and even lag behind some of the Western countries. The Southeast Asian countries show a serious attitude to the development of renewable energy, but their intention to abandon coal still raises some doubts about the methods of implementing this ambitious plan. In particular, it is currently not entirely clear whether these countries are preparing to make a full-fledged "energy transition" in the coming decades, or whether they just intend to replace their coal-fired thermal power plants with gas ones.


2009 ◽  
Vol 11 (1) ◽  
pp. 15-33
Author(s):  
Lynn Thiesmeyer

The Millennium Development Goals are framed within the post-war discourses of development that also gave us Basic Human Needs and Human Security. The Goals set out a consideration of the failures of earlier strategies along with an agenda for the accelerated reduction of poverty and its accompanying human insecurities. Though the more critical aspects of the MDG discourse were sorely needed, they also left space for the repetition of earlier top–down development strategies, and, more generally, for a (re)vision and wider implementation of globalised intervention by developed countries into the less-developed. In this discourse developed countries identify needs on the part of the less-developed and then supply these needs. The ‘need’ discourse focussed on here represents inferior public health that requires services, goods and equipment to be provided by developed countries; what it ignores are negative health consequences that can arise from development schemes themselves.


2020 ◽  
Vol 13 (1) ◽  
pp. 102-118
Author(s):  
N. G. Rogozhina

One of the most important trends in the modern stage of the socio-economic development of the countries of Southeast Asia is the acceleration of the process of urbanization which will determine the future of the region. By 2050, the share of the urban population in the total population of the region is due to increase to 65% compared to 42% at present. The author stresses that the process of urbanization in SEA has a number of distinctive characteristics. Firstly, it should be noted the uneven distribution of the urban population among the countries of the region. Secondly, there is an accelerated growth of medium-sized cities. Thirdly, in the socio-economic and political systems of Southeast Asian countries, large cities and primarily capitals still dominate Being the foundation of economic growth and social progress, urbanization at the same time has many challenges, one of which is the threat of environmental degradation for almost half of the region’s population. With all the diversity of socio-economic development and the political structure of the countries of the region, the environmental situation in their cities, and especially the capitals, is strikingly similar, which indicates the presence of common causes of environmental crisis. The article notes that environmental tension in cities, primarily subjected to problems associated with urbanization, are at the same time a consequence of the national environmental crisis, the cause of which is the realization of a model of extensive economic development, the implementation of which is accompanied by the over-exploitation of natural resources and increased pollution. The deterioration of the environmental situation in cities, which reveals itself in a high level of air and water pollution, restricting public access to drinking water sources and sanitary facilities, increasing the production of solid waste with imperfect disposal technologies, devalues the results of the economic and social progress of Southeast Asian countries.The author discusses in detail the main environmental problems of cities, analyzes the causes of their occurrence and assesses the possibilities for their prevention. The latter involves an integrated approach to overcoming the environmental crisis along with implementing measures at different levels and in different areas. The author comes to the conclusion that despite the fact that in recent years there have been some positive changes in the approach of the authorities to solving the most acute environmental problems, nevertheless, it is doubtful that the environmental situation will noticeably improve in the near future without changing the philosophy of development itself


2020 ◽  
pp. 45-72
Author(s):  
A.P. Muranova ◽  

The article shows the level of ICT development in the Southeast Asian countries, the measures of the governments of these countries for introducing of ICT into tax administration and implementation of ICT for tax payments. According to the author, the panorama of the use of electronic means for tax payments is ambiguous and is determined by a number of economic and social factors. Three groups of countries were accurately designated. The first group consists of technologically developed countries of the region where modern means of tax payments very actively used. The second group consists of less technologically developed countries, where scope of ICT is incomparably narrow. The third group of countries consists of the least developed countries where the tax administration just begins to use ICT.


2020 ◽  
Vol 1 (1) ◽  
pp. 33-42
Author(s):  
William B. Grant

Over the past two decades, the understanding of the roles of vitamin D has expanded to include many nonskeletal effects such as reduced risk of acute respiratory tract infections, autoimmune diseases, cancer, cardiovascular disease, diabetes mellitus, neurological diseases, and adverse pregnancy and birth outcomes. The role of vitamin D for optimal health is well known in Western developed countries but less so in Central Asian countries. This narrative review compares the status of vitamin D between Central Asian countries and Northern European countries. The analysis also summarizes the evidence for the beneficial effects of vitamin D and recommendations for Central Asian countries.


2021 ◽  
Vol 2 (2) ◽  
pp. 133-149
Author(s):  
Aning Kesuma Putri ◽  
Ratu Eva Febriani

The mismatch between jobs and skills indicates the match model in the job market is not going well, which is referred to as (e.g.) labor match, which leads to overeducation and undereducation in the job market. This research was conducted to find the influence of growth, overeducation and undereducation on wages in Southeast Asia. The data used is secondary data sourced from https://ilostat.ilo.org/data/ data in 2010-2019, especially in 8 Southeast Asian countries consisting of Brunai Darusalam, Philippines, Laos, Indonesia, Cambodia, Thailand, Timor Leste and Vietnam. The results found that the workers with the highest undereducated levels were in Timor Laste, then Laos and Cambodia. Worker conditions in developing countries such as Southeast Asia have more undereducation conditions than overeducation. Economic growth, overeducation and undereducatio affect workers' wages. Keywords: overeducation, undereducation, mismatch, labor 


2021 ◽  
Vol 65 (10) ◽  
pp. 91-102
Author(s):  
N. Rogozhina

The choice of the countries of Southeast Asia as an example for analyzing the nature of interaction between developing countries and China within the framework of the Belt and Road Initiative is not accidental. The very logic of China’s stated goals of gaining dominant positions in the world economy and politics makes it inevitable that the countries of Southeast Asia located in geographic proximity to it are included in its long-term economic and political plans. The question, however, is to what extent do they meet the interests of the Southeast Asian countries themselves? The solution to this question is the main subject of research in the article. There are objective prerequisites for mutually beneficial cooperation. The Belt and Road projects are viewed by China as a tool for economic expansion into the region with the prospect of taking a leading position there, using the interest of Southeast Asian countries in the inflow of foreign investment to create modern infrastructure, the lack of which narrows their opportunities for further economic growth, maintaining competitiveness and developing integration ties within ASEAN Community. Expert assessments made by international organizations confirm the positive impact of OBOR projects on the economic development of Southeast Asian countries and although today it is too early to draw any conclusions, since the initiative is only at the initial stage of its implementation in the region, nevertheless the case studies presented in the article indicate a mismatch in the positions of the parties on a number of issues related to the financing of projects, their lack of transparency. non-compliance with environmental and social requirements. The support of the initiative on the part of the Southeast Asian countries does not automatically mean their acceptance of the terms of the agreements proposed by China, which are far from always consistent with their national interests and give rise to fears in society about its expansionist intentions. Therefore, in many Southeast Asian countries, participation in OBOR projects is turning into a subject of political discourse, which reflects the presence of disagreements in society and confrontation of interests regarding the advisability of rapprochement with China, given the associated economic and political risks. The countries of Southeast Asia can be conditionally divided into two groups according to their relation to the Belt and Road initiative. The first group includes Indonesia, Malaysia, Singapore, the Philippines, Thailand, Vietnam and Myanmar, whose position can be described as national pragmatism. While supporting the Chinese initiative in general, they nevertheless assess the possible risks of their participation in projects and seek to reduce them. The second group is represented by Laos and Cambodia, whose leadership unconditionally supports the Chinese initiative, guided by the interests of their own survival, which largely depends on Chinese assistance. Therefore, the prospect of falling into a debt trap and increasing economic dependence on the PRC and even the threat of losing sovereignty does not deter them from participating in highly controversial projects from a commercial point of view. Based on the analysis made, the author comes to the conclusion that, given the existing alignment of political forces in Southeast Asia, China can count on promoting its initiative in the region, which, however, does not automatically lead to an increase in its political influence and to the creation of a China-centric model of regional order. Acknowledgements. The article was prepared within the project “Post-crisis world order: challenges and technologies, competition and cooperation” supported by the grant from Ministry of Science and Higher Education of the Russian Federation program for research projects in priority areas of scientific and technological development (agreement № 075-15-2020-783).


2020 ◽  
Vol 65 (11) ◽  
pp. 45-53
Author(s):  
Thuy Le Thi Bich

The power of each nation is determined by many factors, including the role of its culture. Culture is seen as an effective tool of soft power to affirm the image of our country in the international community. As one of the originating centers of Asian civilization and one of the largest, oldest civilizations in the world, India's soft power exists naturally in its own long historical culture. The Indian epic is considered to be the source of soft power, the link between the world and Indian culture, helping Indian culture expand its influence on other countries and the world. In this article, we focus on presenting the unique features of thinking, soul, thought, and “Indian spirit” reflected in the epic - the source of Indian culture and the epic continuation in countries in Southeast Asia. Thereby, this article helps its readers have a comprehensive view of the Indian epic - the source of “soft power” of Indian culture in Southeast Asian countries to strengthen and develop the relationship between India and other countries in Southeast Asia more and more sustainably and lasting.


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