Primary Aldosteronism due to Unilateral Adrenal Hyperplasia. Report of Two Cases and Review of the Literature.

2000 ◽  
Vol 47 (4) ◽  
pp. 443-449 ◽  
Author(s):  
MASAAKI MORIOKA ◽  
TATSUYA KOBAYASHI ◽  
ATSUSHI SONE ◽  
YOJI FURUKAWA ◽  
HIROYOSHI TANAKA
Keyword(s):  
Primary Aldosteronism ◽  
Review Of The Literature ◽  
Adrenal Hyperplasia ◽  
Unilateral Adrenal Hyperplasia

scholarly journals A Case of Primary Aldosteronism Due to Unilateral Adrenal Hyperplasia

2005 ◽  
Vol 28 (4) ◽  
pp. 379-384 ◽  
Author(s):  
Yasuyuki KATAYAMA ◽  
Nobuki TAKATA ◽  
Taiji TAMURA ◽  
Akemi YAMAMOTO ◽  
Fumihiko HIRATA ◽  
...  
Keyword(s):  
Primary Aldosteronism ◽  
Adrenal Hyperplasia ◽  
Unilateral Adrenal Hyperplasia

Unilateral Adrenal Hyperplasia as a Cause of Primary Aldosteronism

1989 ◽  
Vol 82 (1) ◽  
pp. 82-86 ◽  
Author(s):  
NANCY V. DYE ◽  
NANCY J. LITTON ◽  
MADAN VARMA ◽  
WILLIAM L. ISLEY
Keyword(s):  
Primary Aldosteronism ◽  
Adrenal Hyperplasia ◽  
Unilateral Adrenal Hyperplasia

scholarly journals Unilateral adrenal hyperplasia causing primary aldosteronism: limitations of I-131 norcholesterol scanning

2002 ◽  
Vol 15 (5) ◽  
pp. 459-464 ◽  
Author(s):  
G. A. Mansoor ◽  
C. D. Malchoff ◽  
M. H. Arici ◽  
M. K. Karimeddini ◽  
G. F. Whalen
Keyword(s):  
Primary Aldosteronism ◽  
Adrenal Hyperplasia ◽  
Unilateral Adrenal Hyperplasia

scholarly journals Analysis of Unilateral Adrenal Hyperplasia with Primary Aldosteronism from the Aspect of Messenger Ribonucleic Acid Expression for Steroidogenic Enzymes: A Comparative Study with Adrenal Cortices Adhering to Aldosterone-Producing Adenoma

Endocrinology ◽  
2006 ◽  
Vol 147 (2) ◽  
pp. 999-1006 ◽  
Author(s):  
Kazuto Shigematsu ◽  
Kioko Kawai ◽  
Junji Irie ◽  
Hideki Sakai ◽  
Osamu Nakashima ◽  
...  
Keyword(s):  
Primary Aldosteronism ◽  
Zona Glomerulosa ◽  
Adrenal Hyperplasia ◽  
Steroidogenic Enzymes ◽  
Unilateral Adrenalectomy ◽  
Messenger Ribonucleic Acid ◽  
Unilateral Adrenal Hyperplasia ◽  
Aldosterone Production ◽  
Long Term Follow Up ◽  
Aldosterone Producing Adenoma

Unilateral adrenal hyperplasia with primary aldosteronism is very rare and shows similar endocrine features to aldosterone-producing adenoma and bilateral adrenal hyperplasia. In this study, the mRNA expression of steroidogenic enzymes in unilateral adrenal hyperplasia was examined by in situ hybridization. We found subcapsular micronodules composed of spironolactone body-containing cells, which showed intense expression for 3β-hydroxysteroid dehydrogenase, 11β-hydroxylase, 18-hydroxylase, and 21-hydroxylase but not 17α-hydroxylase, indicating aldosterone production. This expression pattern was the same as that in unilateral multiple adrenocortical micronodules, reported recently. Additionally, it was noted that a nodule with active aldosterone production was closely adjacent to one showing intense 17α-hydroxylase expression. In the adrenal cortices adhering to aldosterone-producing adenoma, the majority of hyperplastic zona glomerulosa and hyperplastic nodules demonstrated a decreased steroidogenic activity. However, minute nodules indicative of active aldosterone production were found at high frequency. These results suggest that the subcapsular micronodules observed might be the root of aldosterone-producing adenoma. Furthermore, we emphasize the need for long-term follow-up after unilateral adrenalectomy or enucleation of the adenoma because of the possibility that buds with autonomous aldosterone production may still be present in the contralateral or remaining adrenal tissue.

scholarly journals Primary Aldosteronism Caused by Unilateral Adrenal Hyperplasia: Rethinking the Accuracy of Imaging Studies

2006 ◽  
Vol 69 (3) ◽  
pp. 125-129 ◽  
Author(s):  
Su-Yu Chen ◽  
Sjen-Jung Shen ◽  
Chien-Wen Chou ◽  
Chwen-Yi Yang ◽  
Hon-Mei Cheng
Keyword(s):  
Primary Aldosteronism ◽  
Adrenal Hyperplasia ◽  
Imaging Studies ◽  
Unilateral Adrenal Hyperplasia

scholarly journals SAT-070 Clinical and Imaging Characteristics of Primary Unilateral Adrenal Hyperplasia in Primary Aldosteronism

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Marcela Rassi-Cruz ◽  
Leticia Vilela ◽  
Luiz Bortolotto ◽  
Luciano Drager ◽  
Maria Adelaide Pereira ◽  
...  
Keyword(s):  
Primary Aldosteronism ◽  
Adrenal Hyperplasia ◽  
Imaging Characteristics ◽  
Unilateral Adrenal Hyperplasia

Hormonal characteristics of primary aldosteronism due to unilateral adrenal hyperplasia

1998 ◽  
Vol 21 (8) ◽  
pp. 531-536 ◽  
Author(s):  
Fumio Otsuka ◽  
F. Otsuka-Misunaga ◽  
S. Koyama ◽  
H. Yamanari ◽  
T. Ogura ◽  
...  
Keyword(s):  
Primary Aldosteronism ◽  
Adrenal Hyperplasia ◽  
Unilateral Adrenal Hyperplasia
Sign in / Sign up

Export Citation Format

Share Document