scholarly journals Inhibition of Ovarian Follicular Development Associated with a Decrease in Luteinizing Hormone Levels During the Estrous Cycle of the Rat.

1998 ◽  
Vol 45 (4) ◽  
pp. 539-546 ◽  
Author(s):  
KOJI ARAI ◽  
KEN-ICHI OHSHIMA ◽  
GEN WATANABE ◽  
KATSUHIKO ARAI ◽  
KOHKICHI UEHARA ◽  
...  
Keyword(s):  
Luteinizing Hormone ◽  
Estrous Cycle ◽  
Follicular Development ◽  
Hormone Levels ◽  
Ovarian Follicular Development

Ovarian Follicular Development during the Estrous Cycle in Gilts following Electrocautery of Follicles

1975 ◽  
Vol 41 (4) ◽  
pp. 1105-1111 ◽  
Author(s):  
James R. Clark ◽  
Neal L. First ◽  
Arthur B. Chapman ◽  
Lester E. Casida
Keyword(s):  
Estrous Cycle ◽  
Follicular Development ◽  
Ovarian Follicular Development

scholarly journals Beneficial Effects of Decreased Meal Frequency on Nutrient Utilization, Secretion of Luteinizing Hormone and Ovarian Follicular Development in Gilts

2020 ◽  
Author(s):  
Lun Hua ◽  
Lianpeng Zhao ◽  
Zhengyu Mao ◽  
Wentao Li ◽  
Jing Li ◽  
...  
Keyword(s):  
Luteinizing Hormone ◽  
Time Course ◽  
Average Daily Gain ◽  
Amino Nitrogen ◽  
Follicular Development ◽  
Nutrient Utilization ◽  
Metabolic Status ◽  
Meal Frequency ◽  
Meal Test ◽  
Ovarian Follicular Development

Abstract Background: The replacement gilts are typically fed ad libitum, whereas emerging evidence in human and rodent studies revealed that time-restricted access to food had health benefits. The objective of this study was to investigate the effect of meal frequency on metabolic status and ovarian follicular development in gilts.Methods: A total of 36 gilts (Landrace × Yorkshire) at age of 150 (±3) d and bodyweight at 77.6 (±3.8) kg were randomly allocated into one of three meal frequencies (n = 12) to feed one meal (T1); two meals (T2), or six meals per day (T6) for a consecutive 14 weeks. The effect of meal frequency on growth preference, nutrient utilization, gut microbial metabolite short-chain fatty acids production at a 3-h interval, dynamics of metabolic status after a meal test, reproductive hormone secretions, and ovarian follicular development were measured in gilts.Results: Gilts in T1 group had greater average daily gain (+48 g/d, P < 0.05) and bodyweight (+4.9kg, P < 0.05) than T6 gilts. The apparent digestibilities of dry matter, crude protein, ether extract, ash and gross energy were not affected by meal frequency, except for a greater NDF digestibility in T1 gilts than T6 gilts (P < 0.05). Nitrogen balance trail reveal that the T1 gilts had lower urine excretion of nitrogen (-8.17 g/d, P < 0.05) and had a greater nitrogen retention (+9.81 g/d, P < 0.05), resulting in greater nitrogen utilization compared with T6 gilts. The time-course dynamics of glucose, α-amino nitrogen, urea, lactate, and insulin levels in serum revealed a greater utilization of nutrients after a meal test in T1 gilts than T2 or T6 gilts. The T1 gilts showed greater acetate content in feces compared with the other two groups (P < 0.05). The age, bodyweight and backfat thickness at first puberty of gilts were not affected by meal frequency, but gilts in T1 group had greater serum levels of luteinizing hormone and 17β-estradiol, a larger number of growing follicles and corpora lutea, and higher mRNA expression levels of genes related to follicular development on the 18th day of the 3rd estrus cycle.Conclusions: The current findings revealed unexpected benefits of meal frequency at one meal per day on the nutrient utilizations and reproductive function for replacement gilts, thus providing new insights into the nutritional strategy for replacement gilts, as well as the dietary pattern for other mammals, such as human.

Effect of hypothyroidism on ovarian follicular development, granulosa cell proliferation and peripheral hormone levels in the prepubertal rat

1996 ◽  
Vol 134 (5) ◽  
pp. 649-654 ◽  
Author(s):  
Grietje Dijkstra ◽  
Dirk G de Rooij ◽  
Frank H de Jong ◽  
Robert van den Hurk
Keyword(s):  
Cell Proliferation ◽  
Granulosa Cell ◽  
Granulosa Cells ◽  
Ovarian Development ◽  
Follicular Development ◽  
Corpora Lutea ◽  
Hormone Levels ◽  
Antral Follicles ◽  
Ovarian Follicular Development ◽  
Serum Tsh

Dijkstra G, de Rooij DG, de Jong FH, van den Hurk R. Effect of hypothyroidism on ovarian follicular development, granulosa cell proliferation and peripheral hormone levels in the prepubertal rat. Eur J Endocrinol 1996;134:649–54. ISSN 0804–4643 The aim of this study was to examine the effects of prepubertal hypothyroidism on ovarian development in rats. Therefore, from birth up to day 40 postpartum, rats were given 6-propyl-2-thiouracil (PTU) via the drinking water of mothers and pups. At ages ranging from 12 to 40 days, ovarian weights were measured and serum was collected to estimate thyrotrophin (TSH), folliclestimulating hormone (FSH) and inhibin levels. Two hours before sacrifice the animals received an injection of bromodeoxyuridine (BrdU) to estimate the proliferative activity of the follicular granulosa cells. Ovaries were fixed in Carnoy's fluid and follicle counts were performed on sections stained with anti-BrdU and with haematoxylin and eosin. The PTU treatment resulted in increased serum TSH levels, indicative of hypothyroidism, and markedly lower body and ovarian weights, whereas serum FSH and inhibin levels were hardly affected. At day 40, ovaries of PTU-treated animals contained relatively more secondary and less antral follicles, smaller non-atretic antral follicles and more atretic follicles when compared with untreated rats, while corpora lutea were absent. It is concluded that this disturbed folliculogenesis is due to inadequate thyroid hormone supply, which hampers the differentiation and not the proliferation of granulosa cells because diameters of antral follicles were significantly smaller whereas the BrdU-labelling index had not changed. Robert van den Hurk, Department of Functional Morphology, Faculty of Veterinary Medicine, PO Box 80.157, 3508 TD Utrecht, The Netherlands

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