Work systems as the core of the design space for organisational design and engineering

2010 ◽  
Vol 1 (1/2) ◽  
pp. 5 ◽  
Author(s):  
Steven Alter
Keyword(s):  
Design Space ◽  
Work Systems ◽  
The Core ◽  
Organisational Design

Optimal Non-Uniform Parametrization for Fourier Descriptor Based Path Synthesis of Four Bar Mechanisms

2018 ◽  
Author(s):  
Shashank Sharma ◽  
Anurag Purwar ◽  
Q. Jeffrey Ge
Keyword(s):  
Input Data ◽  
Design Space ◽  
Fourier Descriptors ◽  
Fourier Descriptor ◽  
Loop Closure ◽  
The Core ◽  
Closure Equation ◽  
Harmonic Decomposition ◽  
Path Synthesis

Fourier descriptor based path synthesis algorithms rely on harmonic decomposition of four-bar loop closure equation to split the design space into smaller subsets. The core of the methodology depends on calculation and fitting of Fourier descriptors. However, a uniform time parametrization is assumed in existing literature. This paper aims to explore the use of non-uniform time parametrization of input data and calculation of an optimal parametrization. Additionally, design-centric constraints have been proposed to give user enhanced control over coupler speed. As a result, this work improves the existing algorithm tremendously.

Corrugation and Buckling Defects in Wound Rolls

2005 ◽  
Vol 128 (1) ◽  
pp. 56-64 ◽  
Author(s):  
P. M. Lin ◽  
J. A. Wickert
Keyword(s):  
Design Space ◽  
Elastic Stability ◽  
Internal Stresses ◽  
Core System ◽  
The Core ◽  
Acceptable Quality ◽  
Wound Rolls ◽  
Winding Tension ◽  
Elastic Shear ◽  
The Web

Sheet metal, paper, and polymer webs are often stored and processed as large rolls comprising thousands of layers. Depending on the elastic properties of the web material, the roll’s dimensions, the type of core, and the winding tension, the stresses that develop within the roll can be sufficiently high to cause local or gross buckling defects to form. For instance, the cylindrical core onto which the web is wound can collapse, a failure mode that is termed “v-buckling.” In other cases, while the core might remain intact, a group of layers interior to the roll can wrinkle into a near-sinusoidal corrugated pattern around the circumference. This paper examines such “starring” defects analytically and experimentally. Measurements on a laboratory-scale web transport system are used to validate the model, and to identify conditions where no defects occur and the roll has acceptable quality, where starring patterns develop, and where v-buckling occurs. For particular core and web materials, the tension and diameter are the primary variables that influence the roll’s stability, and demarcations between stable and buckled configurations are identified in the tension-diameter design space. A model for the elastic stability of the roll-core system is developed, in which the corrugated layers are treated as multiple rings subjected to the resultant pressure generated by the roll’s internal stresses, and to the elastic support provided by the core and neighboring web layers. At the onset of corrugation, adjacent web layers couple through surface contact which is incorporated in the model as an elastic shear layer.

Optimization of multi-sandwich-panel composite structures for minimum weight with strength and buckling considerations

2018 ◽  
Vol 25 (2) ◽  
pp. 229-241 ◽  
Author(s):  
Hai-Tao Fan ◽  
Hai Wang ◽  
Xiu-Hua Chen
Keyword(s):  
Composite Structures ◽  
Sandwich Panel ◽  
Maximum Stress ◽  
Design Space ◽  
Minimum Weight ◽  
Sandwich Panels ◽  
Stacking Sequence ◽  
Genetic Operators ◽  
Stress Criterion ◽  
The Core

AbstractA genetic algorithm-based method is proposed to globally optimize the stacking sequence of multi-sandwich-panel composite structures for minimum weight with strength and buckling considerations. The prerequisites for the continuity between sandwich panels are first studied. To implement the summarized continuity rules in the evolutionary optimization, three newly constructed chromosomes are developed to encode the global stacking sequence with no additional repair. Genetic operators, including specialized mutation, swapping and crossover operators, are also developed to effectively explore the design space and keep the continuity rules followed. The Hashin criterion and maximum stress criterion are used to evaluate the strength of sandwich panels. A typical multi-sandwich-panel composite structure with identical and different core thicknesses is optimized to verify the validity and efficiency of the proposed method. It is found that much lighter solutions are obtained with an acceptable efficiency in all cases. It is also found that the weight of the multi-sandwich-panel composite structures can be further reduced when the core thicknesses are not identical.

What face familiarity feelings say about the lateralization of specific entities within the core system

2019 ◽  
Vol 42 ◽  
Author(s):  
Guido Gainotti
Keyword(s):  
Temporal Lobe ◽  
Memory System ◽  
Core System ◽  
The Core ◽  
Memory Traces ◽  
Specific Memory ◽  
Target Article ◽  
Temporal Structures ◽  
The Right

Abstract The target article carefully describes the memory system, centered on the temporal lobe that builds specific memory traces. It does not, however, mention the laterality effects that exist within this system. This commentary briefly surveys evidence showing that clear asymmetries exist within the temporal lobe structures subserving the core system and that the right temporal structures mainly underpin face familiarity feelings.

A scanning electron microscopic study on dissolving process of cholesterol gallstones by chenodeoxycholic acid (CDCA)

1978 ◽  
Vol 36 (2) ◽  
pp. 522-523
Author(s):  
T. Kanetaka ◽  
M. Cho ◽  
S. Kawamura ◽  
T. Sado ◽  
K. Hara
Keyword(s):  
Electron Microscope ◽  
Chenodeoxycholic Acid ◽  
Outer Surface ◽  
Electron Microscopic ◽  
Cholesterol Gallstones ◽  
The Core ◽  
Scanning Electron Microscopic Study ◽  
Scanning Electron Microscopic ◽  
Acceleration Voltage ◽  
Scanning Electron

The authors have investigated the dissolution process of human cholesterol gallstones using a scanning electron microscope(SEM). This study was carried out by comparing control gallstones incubated in beagle bile with gallstones obtained from patients who were treated with chenodeoxycholic acid(CDCA).The cholesterol gallstones for this study were obtained from 14 patients. Three control patients were treated without CDCA and eleven patients were treated with CDCA 300-600 mg/day for periods ranging from four to twenty five months. It was confirmed through chemical analysis that these gallstones contained more than 80% cholesterol in both the outer surface and the core.The specimen were obtained from the outer surface and the core of the gallstones. Each specimen was attached to alminum sheet and coated with carbon to 100Å thickness. The SEM observation was made by Hitachi S-550 with 20 kV acceleration voltage and with 60-20, 000X magnification.

The Structure and Development of Microbodies in the Fat Body and other Tissues of an Insect (Calpodes Ethlius)

1970 ◽  
Vol 28 ◽  
pp. 148-149
Author(s):  
M. Locke ◽  
J. T. McMahon
Keyword(s):  
Electron Microscopy ◽  
Liquid Crystals ◽  
Fat Body ◽  
Competitive Inhibitor ◽  
Dense Core ◽  
Urate Oxidase ◽  
Blood Proteins ◽  
Free Base ◽  
The Core ◽  
The Matrix

The fat body of insects has always been compared functionally to the liver of vertebrates. Both synthesize and store glycogen and lipid and are concerned with the formation of blood proteins. The comparison becomes even more apt with the discovery of microbodies and the localization of urate oxidase and catalase in insect fat body.The microbodies are oval to spherical bodies about 1μ across with a depression and dense core on one side. The core is made of coiled tubules together with dense material close to the depressed membrane. The tubules may appear loose or densely packed but always intertwined like liquid crystals, never straight as in solid crystals (Fig. 1). When fat body is reacted with diaminobenzidine free base and H2O2 at pH 9.0 to determine the distribution of catalase, electron microscopy shows the enzyme in the matrix of the microbodies (Fig. 2). The reaction is abolished by 3-amino-1, 2, 4-triazole, a competitive inhibitor of catalase. The fat body is the only tissue which consistantly reacts positively for urate oxidase. The reaction product is sharply localized in granules of about the same size and distribution as the microbodies. The reaction is inhibited by 2, 6, 8-trichloropurine, a competitive inhibitor of urate oxidase.

Exsolution and inversion in pigeonite from the Whin Sill, Northern England

1978 ◽  
Vol 36 (1) ◽  
pp. 474-475
Author(s):  
P.P.K. Smith
Keyword(s):  
High Temperature ◽  
Low Temperature ◽  
Homogeneous Nucleation ◽  
Silicate Mineral ◽  
Antiphase Boundaries ◽  
Two Phase ◽  
Primitive Form ◽  
The Core ◽  
Nucleation Mechanisms ◽  
And Inversion

Grains of pigeonite, a calcium-poor silicate mineral of the pyroxene group, from the Whin Sill dolerite have been ion-thinned and examined by TEM. The pigeonite is strongly zoned chemically from the composition Wo8En64FS28 in the core to Wo13En34FS53 at the rim. Two phase transformations have occurred during the cooling of this pigeonite:- exsolution of augite, a more calcic pyroxene, and inversion of the pigeonite from the high- temperature C face-centred form to the low-temperature primitive form, with the formation of antiphase boundaries (APB's). Different sequences of these exsolution and inversion reactions, together with different nucleation mechanisms of the augite, have created three distinct microstructures depending on the position in the grain.In the core of the grains small platelets of augite about 0.02μm thick have farmed parallel to the (001) plane (Fig. 1). These are thought to have exsolved by homogeneous nucleation. Subsequently the inversion of the pigeonite has led to the creation of APB's.

Intramitochondrial Viruses of Reptilian Cell Origin

1972 ◽  
Vol 30 ◽  
pp. 318-319
Author(s):  
Philip D. Lunger ◽  
H. Fred Clark
Keyword(s):  
Particle Production ◽  
Outer Zone ◽  
Density Variation ◽  
Core Region ◽  
Mitochondrial Membranes ◽  
Virus Particles ◽  
The Core ◽  
Vipera Russelli ◽  
Maturation Stages ◽  
Type Particle

In the course of fine structure studies of spontaneous “C-type” particle production in a viper (Vipera russelli) spleen cell line, designated VSW, virus particles were frequently observed within mitochondria. The latter were usually enlarged or swollen, compared to virus-free mitochondria, and displayed a considerable degree of cristae disorganization.Intramitochondrial viruses measure 90 to 100 mμ in diameter, and consist of a nucleoid or core region of varying density and measuring approximately 45 mμ in diameter. Nucleoid density variation is presumed to reflect varying degrees of condensation, and hence maturation stages. The core region is surrounded by a less-dense outer zone presumably representing viral capsid.Particles are usually situated in peripheral regions of the mitochondrion. In most instances they appear to be lodged between loosely apposed inner and outer mitochondrial membranes.

Bonafide Substructure in the Core of Ferritin

1985 ◽  
Vol 43 ◽  
pp. 322-323
Author(s):  
William H. Massover
Keyword(s):  
Phase Contrast ◽  
Central Cavity ◽  
Amplitude Image ◽  
Ultrastructural Studies ◽  
The Core ◽  
Hydrated Ferric Oxide ◽  
Imaging Artifact ◽  
Contrast Image ◽  
Protein Shell ◽  
Regular Patterns

Each molecule of ferritin (d = 130Å) contains a core of iron surrounded by a 24-subunit protein shell. The amount of iron stored is variable and is present within the central cavity (d = 80Å) as a hydrated ferric oxide equivalent to the mineral, ferrihydrite. Many early ultrastructural studies of ferritin detected regular patterns of a multiparticulate substructure in the iron-rich core [e.g., 3,4], Each small particle was termed a “micelle“; a theory became widely accepted that a core consisted of up to six micelles positioned at the vertices of an octahedron. Other workers recognized that the apparent micelles were smaller or even disappeared if images were recorded closer to exact focus [e.g., 5]. In 1969, Haydon clearly established that the observed substructure was really an imaging artifact; each apparent micelle was only a dot in the underfocused phase contrast image of the supporting film superimposed on the amplitude image of the strongly scattering metal.

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