scholarly journals Internalisation of core-shell superparamagnetic nanoparticles into human granulocytes

2016 ◽  
Vol 13 (8/9) ◽  
pp. 659 ◽  
Author(s):  
F. De Angelis ◽  
G. Berardi ◽  
F.A. Scaramuzzo ◽  
M. Liberatore ◽  
M. Barteri
Keyword(s):  
Superparamagnetic Nanoparticles ◽  
Core Shell ◽  
Human Granulocytes

Efficient strategy to increase the surface functionalization of core–shell superparamagnetic nanoparticles using dendron grafting

2008 ◽  
Vol 32 (3) ◽  
pp. 383 ◽  
Author(s):  
Karine Heuzé ◽  
Daniel Rosario-Amorin ◽  
Sylvain Nlate ◽  
Manuel Gaboyard ◽  
Anthony Bouter ◽  
...  
Keyword(s):  
Surface Functionalization ◽  
Superparamagnetic Nanoparticles ◽  
Core Shell ◽  
Efficient Strategy

Fabrication of Core-shell Type FeCo-Au (Ag) High Moment Magnetic Nanoparticles

2005 ◽  
Vol 877 ◽  
Author(s):  
Jianmin Bai ◽  
Yunhao Xu ◽  
Jian-Ping Wang
Keyword(s):  
Deposition Process ◽  
Superparamagnetic Nanoparticles ◽  
Core Shell ◽  
Physical Vacuum ◽  
Shell Type ◽  
On Line ◽  
High Magnetic Moment ◽  
20 Nm ◽  
Controllable Particle Size ◽  
Feco Nanoparticles

AbstractWe developed a physical vacuum deposition technique combining an on-line sputtering/evaporation process with an integrated nanocluster deposition process to prepare core-shell type nanoparticles. High magnetic moment (Fe60Co40)coreAushell and (Fe60Co40)coreAgshell superparamagnetic nanoparticles with controllable particle size of 10 – 20 nm and Au/Ag shell thickness of 1 – 3 nm were prepared successfully by using method. Au shell is not only functional for the potential biocompatibility but also the key to prevent oxidation of FeCo nanoparticles. Saturation magnetization of (Fe60Co40)coreAushell nanoparticles was found three times higher than that of iron oxide nanoparticles. This novel technique enables us to control independently the dimensions of core and shell and select individually materials for core and shell for other core-shell type nanoparticles.

The Preparation and Characteristic of Superparamagnetic Core/Shell Nanoparticles

2013 ◽  
Vol 274 ◽  
pp. 432-435
Author(s):  
Hong Xia Shen ◽  
Zheng Zhi Yin ◽  
Qiong Cheng
Keyword(s):  
Biomedical Applications ◽  
Superparamagnetic Nanoparticles ◽  
Bioactive Molecules ◽  
Core Shell ◽  
Shell Nanoparticles ◽  
X Ray ◽  
Transmission Electron ◽  
Vibration Sample Magnetometer ◽  
Diffraction Patterns ◽  
Core Shell Nanoparticles

Superparamagnetic core/shell nanoparticles have been prepared successfully by the reduction of Au3+ onto the surface of superparamagnetic nanoparticles. The core/shell nanoparticles were characterized by Transmission electron microscopy (TEM), X-ray powder diffraction patterns (XRD), UV–vis spectrophotometer, Vibration Sample Magnetometer(VSM) and micro-confocal Raman system. The results revealed that the prepared core/shell nanoparticles were covered by Au shell. These superparamagnetic nanoparticles can be highly sensitively detected and afford new opportunities for biomedical applications through chemical bonding of bioactive molecules with the Au shell of nanoparticles.

scholarly journals Enzyme immobilised novel core–shell superparamagnetic nanocomposites for enantioselective formation of 4-(R)-hydroxycyclopent-2-en-1-(S)-acetate

2014 ◽  
Vol 50 (76) ◽  
pp. 11185-11187 ◽  
Author(s):  
Maneea Eizadi Sharifabad ◽  
Ben Hodgson ◽  
Mourad Jellite ◽  
Tim Mercer ◽  
Tapas Sen
Keyword(s):  
Surface Area ◽  
High Surface ◽  
High Surface Area ◽  
Superparamagnetic Nanoparticles ◽  
Core Shell ◽  
One Step

One step conversion of meso-cyclopent-2-en-1,4-diacetate to pharmaceutically important chiral isomers using enzymes immobilised novel high surface area core–shell superparamagnetic nanoparticles.

scholarly journals Controllable Engineering and Functionalizing Nanoparticles with Specific Targeting Capability

2021 ◽  
Author(s):  
Zhanchen Guo ◽  
Rongrong Xing ◽  
Zhen Liu
Keyword(s):  
Breast Cancer ◽  
Biomedical Applications ◽  
High Specificity ◽  
Superparamagnetic Nanoparticles ◽  
Breast Cancer Cell Lines ◽  
Core Shell ◽  
Shell Nanoparticles ◽  
Specific Targeting ◽  
Dual Functional ◽  
Core Shell Nanoparticles

Abstract Due to unique properties, nanoparticles been widely used in important biomedical applications such as imaging, drug delivery and disease therapy. Targeting toward specific proteins is essential for the effective utilization of nanoparticles. However, current targeting strategies mainly rely on surface modification with bio-ligands, which often not only fail to provide desired properties but also remain challenging. Here we report an unprecedented approach, called reverse microemulsion-confined epitope-oriented surface imprinting and cladding (ROSIC), for facile, versatile and controllable engineering coreless and core/shell nanoparticles with tunable monodispersed size as well as specific targeting capability towards proteins and peptides. Via engineering coreless imprinted and cladded silica nanoparticles, the effectiveness and superiority over conventional imprinting of the proposed approach was first verified. The prepared nanoparticles exhibited both high specificity and high affinity. Using quantum dots (QDs), superparamagnetic nanoparticles, silver nanoparticles and upconverting nanoparticles as a representative set of core substrates, a variety of dual-functional single-core/shell nanoparticles were then successfully prepared. Finally, selective fluorescence imaging of triple negative breast cancer cells over other breast cancer cell lines using QD-cored nanoparticles was achieved, which well demonstrated the potential of the prepared core/shell nanoparticles in biomedical applications. Thus, this approach opened a new avenue to engineering and functionalization of advanced nanoparticles with targeting capability, holding great prospects in biomedical applications.

scholarly journals Preparation of Dual-Layered Core–Shell Fe3O4@SiO2 Nanoparticles and Their Properties of Plasmid DNA Purification

Nanomaterials ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 3422
Author(s):  
Jin Soon Han ◽  
Gye Seok An
Keyword(s):  
Plasmid Dna ◽  
Room Temperature ◽  
Sio2 Nanoparticles ◽  
Superparamagnetic Nanoparticles ◽  
Core Shell ◽  
Dense Layer ◽  
Sio2 Coating ◽  
Sio2 Shell ◽  
Rapid Purification ◽  
Superparamagnetic Properties

The rapid purification of biomaterials such as DNA, RNA, and antibodies has attracted extensive attention, and research interest has increased further with the COVID-19 pandemic. In particular, core–shell-structured superparamagnetic nanoparticles have been continuously studied for their application as biopurification materials. It has been reported that Fe3O4@SiO2 nanoparticles are one of the most promising candidates for separating nucleic acids via a simple and rapid process. This study proposed a fabrication method for dual-layered Fe3O4@SiO2 nanoparticles, in which the density of the SiO2 shell was controlled using an intermediate surfactant during the SiO2 coating. After the fabrication of dual-layered Fe3O4@SiO2 nanoparticles, structural, morphological, and magnetic analyses were conducted. The results showed that the Fe3O4 nanoparticles were surrounded by a dense layer 15.6~27.9 nm thick and a porous layer 24.2~44.4 nm thick, and had superparamagnetic properties with high saturated magnetization at room temperature (86.9 emu/g). Then, the optimal conditions for the biopurification material were suggested based on analysis of the selective separation of plasmid DNA.

A Novel Method for the Synthesis of Core-shell Magnetic Nanoparticle

2016 ◽  
Vol 66 (4) ◽  
pp. 291 ◽  
Author(s):  
D. Mukherji
Keyword(s):  
Magnetic Nanoparticles ◽  
Contrast Agent ◽  
Synthesis Method ◽  
Chemical Separation ◽  
Magnetic Core ◽  
Superparamagnetic Nanoparticles ◽  
Iron Oxide Nanoparticle ◽  
Core Shell ◽  
Shell Type ◽  
Wide Range

<p>Core-shell type magnetic nanoparticles are finding attractive applications in biomedicine, from diagnostic to cancer therapy. Both for targeted drug delivery and hyperthermia, as well as a contrast agent used for external biomedical imaging systems, small (&lt; 20 nm) superparamagnetic nanoparticles are desired. Some iron oxide nanoparticle formulations are already approved for human administration as contrast agent for magnetic resonance imaging. However, search continues for nanoparticles with higher saturation magnetisation. Metallic, bi-metallic and intermetallic magnetic nanoparticles are finding attention. Biocompatibility and optimal clearance are important criteria for the medical applications and therefore core-shell type particles are favored, where a biocompatible shell (e.g. polymer, Silica) can prevent inadvertent host reaction with the magnetic core. A recently developed novel synthesis method (electrochemical selective phase dissolution - ESPD), which can produce core-shell magnetic nanoparticles, is reviewed in this paper. ESPD, as the name suggests, uses electro-chemical separation of a phase from metallic alloys to synthesize nanoparticles. It is a versatile method and can be adopted to produce a wide range of nanostructures in addition to the core-shell magnetic nanoparticles.</p>

Superparamagnetic core–shell radical polymer brush as efficient catalyst for oxidation of alcohols to aldehydes and ketones

RSC Advances ◽  
2016 ◽  
Vol 6 (68) ◽  
pp. 63472-63476 ◽  
Author(s):  
Jian-Jhe Yang ◽  
Chia-Chen Li ◽  
Yi-Fei Yang ◽  
Chan-Yang Wang ◽  
Chun-Hao Lin ◽  
...  
Keyword(s):  
Catalytic Oxidation ◽  
Polymer Brush ◽  
Superparamagnetic Nanoparticles ◽  
Core Shell ◽  
Efficient Catalyst ◽  
Oxidation Of Alcohols ◽  
Aldehydes And Ketones

The conversion of catalytic oxidation of alcohols to aldehydes and ketones is more than 99% using a nitroxide polymer brush grafted on superparamagnetic nanoparticles as a catalyst. The catalyst can be easily recovered and reused.

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