scholarly journals Microcontroller based low-cost device for quartz crystal microbalance

2011 ◽  
Vol 57 (1.2) ◽  
pp. 1-8
Author(s):  
ARI Fikret; NAZIR
Keyword(s):  
Quartz Crystal Microbalance ◽  
Quartz Crystal ◽  
Low Cost

scholarly journals A Real-Time Method for Improving Stability of Monolithic Quartz Crystal Microbalance Operating under Harsh Environmental Conditions

Sensors ◽  
2021 ◽  
Vol 21 (12) ◽  
pp. 4166
Author(s):  
Román Fernández ◽  
María Calero ◽  
Yolanda Jiménez ◽  
Antonio Arnau
Keyword(s):  
Real Time ◽  
Quartz Crystal Microbalance ◽  
Quartz Crystal ◽  
Limit Of Detection ◽  
Quartz Substrate ◽  
Low Cost ◽  
Discrete Wavelet ◽  
Reagent Consumption ◽  
Measurement Cell ◽  
The Stability

Monolithic quartz crystal microbalance (MQCM) has recently emerged as a very promising technology suitable for biosensing applications. These devices consist of an array of miniaturized QCM sensors integrated within the same quartz substrate capable of detecting multiple target analytes simultaneously. Their relevant benefits include high throughput, low cost per sensor unit, low sample/reagent consumption and fast sensing response. Despite the great potential of MQCM, unwanted environmental factors (e.g., temperature, humidity, vibrations, or pressure) and perturbations intrinsic to the sensor setup (e.g., mechanical stress exerted by the measurement cell or electronic noise of the characterization system) can affect sensor stability, masking the signal of interest and degrading the limit of detection (LoD). Here, we present a method based on the discrete wavelet transform (DWT) to improve the stability of the resonance frequency and dissipation signals in real time. The method takes advantage of the similarity among the noise patterns of the resonators integrated in an MQCM device to mitigate disturbing factors that impact on sensor response. Performance of the method is validated by studying the adsorption of proteins (neutravidin and biotinylated albumin) under external controlled factors (temperature and pressure/flow rate) that simulate unwanted disturbances.

scholarly journals Application of Tamm Plasmon Polaritons and Cavity Modes for Biosensing in the Combined Spectroscopic Ellipsometry and Quartz Crystal Microbalance Method

Biosensors ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 501
Author(s):  
Ieva Plikusienė ◽  
Ernesta Bužavaitė-Vertelienė ◽  
Vincentas Mačiulis ◽  
Audrius Valavičius ◽  
Almira Ramanavičienė ◽  
...  
Keyword(s):  
Quartz Crystal Microbalance ◽  
Spectroscopic Ellipsometry ◽  
Quartz Crystal ◽  
Cavity Mode ◽  
Low Cost ◽  
Optical Signal ◽  
Sensor Chip ◽  
Optical Biosensing ◽  
Cavity Modes ◽  
Plasmon Polaritons

Low-cost 1D plasmonic photonic structures supporting Tamm plasmon polaritons and cavity modes were employed for optical signal enhancement, modifying the commercially available quartz crystal microbalance with dissipation (QCM-D) sensor chip in a combinatorial spectroscopic ellipsometry and quartz microbalance method. The Tamm plasmon optical state and cavity mode (CM) for the modified mQCM-D sample obtained sensitivity of ellipsometric parameters to RIU of ΨTPP = 126.78 RIU−1 and ΔTPP = 325 RIU−1, and ΨCM = 264 RIU−1 and ΔCM = 645 RIU‑1, respectively. This study shows that Tamm plasmon and cavity modes exhibit about 23 and 49 times better performance of ellipsometric parameters, respectively, for refractive index sensing than standard spectroscopic ellipsometry on a QCM-D sensor chip. It should be noted that for the optical biosensing signal readout, the sensitivity of Tamm plasmon polaritons and cavity modes are comparable with and higher than the standard QCM-D sensor chip. The different origin of Tamm plasmon polaritons (TPP) and cavity mode (CM) provides further advances and can determine whether the surface (TPP) or bulk process (CM) is dominating. The dispersion relation feature of TPP, namely the direct excitation without an additional coupler, allows the possibility to enhance the optical signal on the sensing surface. To the best of our knowledge, this is the first study and application of the TPP and CM in the combinatorial SE-QCM-D method for the enhanced readout of ellipsometric parameters.

A highly sensitive quartz crystal microbalance sensor assisted with ZnO nanosheets for nerve agent detection

2021 ◽  
pp. 2151020
Author(s):  
Dong In Kim ◽  
Rak Hyun Jeong ◽  
Ji Won Lee ◽  
Seong Park ◽  
Jin-Hyo Boo
Keyword(s):  
Specific Surface ◽  
Surface Area ◽  
Quartz Crystal Microbalance ◽  
Specific Surface Area ◽  
Polyvinylidene Fluoride ◽  
Quartz Crystal ◽  
Low Cost ◽  
Nerve Agent ◽  
Quartz Crystal Microbalance Sensor ◽  
Zno Nanosheets

ZnO is known as a promising material for surface acoustic wave (SAW) sensor devices because of its piezoelectric property. Recently, quartz crystal microbalances (QCMs) have been promising as a sensor platform due to their high sensitivity and ease of measurement. In particular, the alignment of ZnO nanosheets (NSs) into ordered nanoarrays is expected to improve the device sensitivity and stability due to large specific surface area, which allows the captured significant quantities of gas molecules. In this study, we fabricated a quartz crystal microbalance sensor with ZnO NSs structures using polyvinylidene fluoride as a receptor for nerve agent detection. We synthesized two-dimensional NSs by chemical bath deposition (CBD) via the potassium hydroxide etching method. CBD is an excellent method that can easily form uniform structures at low cost. We fabricated ZnO NSs modified with polyvinylidene fluoride and used it for detection of dimethyl methylphosphonate (DMMP) gas. The NSs structure indicated that, when a similar functional group material is coated, the specific surface area increased compared to the nanorods (NRs) structure. As a result, the sensitivity of the quartz crystal microbalance sensor to DMMP gas was improved.

DESIGN OF A SIMPLE LOW-COST QUARTZ CRYSTAL MICROBALANCE SYSTEM

2013 ◽  
Vol 41 (5) ◽  
pp. 473-489 ◽  
Author(s):  
M. M. Kamel ◽  
M. K. El Nimr ◽  
S. T. Assar ◽  
A. S. Atlam
Keyword(s):  
Quartz Crystal Microbalance ◽  
Quartz Crystal ◽  
Low Cost

scholarly journals A Portable, Label-Free, Reproducible Quartz Crystal Microbalance Immunochip for the Detection of Zearalenone in Food Samples

Biosensors ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 53
Author(s):  
Shengmiao Liu ◽  
Xinyu Liu ◽  
Qianwen Pan ◽  
Zhihan Dai ◽  
Mingfei Pan ◽  
...  
Keyword(s):  
Frequency Response ◽  
Quartz Crystal Microbalance ◽  
Quartz Crystal ◽  
Low Cost ◽  
High Specificity ◽  
Food Samples ◽  
Soy Sauce ◽  
Label Free ◽  
Qualitative Detection ◽  
Application Frequency

This research reports a portable immunochip, based on quartz crystal microbalance (QCM) for label-free, low-cost qualitative detection of zearalenone (ZEN) in food samples. The experimental parameters in the functionalization and working process were evaluated in detail, in order to achieve a high accuracy and sensitivity. Under optimal conditions, the ZEN concentration at an inhibition ratio of 50% and 15% of the proposed QCM immunochip achieved 3.41 µg L−1 and 0.37 µg L−1, respectively. This portable QCM immunochip also exhibited high specificity, no obvious cross-reaction to five structural analogs of ZEN, and showed other mycotoxins. It could finish the whole qualitative measurement within 30 min, showed good stability during the processes of preparation (SD < 5%, n = 9), storage (frequency response >90%, in PBS at 4 °C for 15 days), and application (frequency response >90% after being reused 6 times). The developed QCM immunochip obtained accurate and repeatable recovery results in ZEN analysis in the chosen food samples (corn, wheat flour, soy sauce, and milk), which had a high correlation (R2 = 0.9844) with that achieved by the HPLC–MS/MS method. In short, this work developed a portable, stable, and reproducible QCM immunochip that could be used for rapid, low-cost, and sensitively measurement of ZEN content in real food samples.

Low-cost scalable quartz crystal microbalance array for environmental sensing

2016 ◽  
Author(s):  
Eric S. Muckley ◽  
Cristain Anazagasty ◽  
Christopher B. Jacobs ◽  
Tibor Hianik ◽  
Ilia N. Ivanov
Keyword(s):  
Quartz Crystal Microbalance ◽  
Quartz Crystal ◽  
Low Cost ◽  
Environmental Sensing
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