scholarly journals Pressure-decay testing of pleural air leaks in intact murine lungs: evidence for peripheral airway regulation

2018 ◽  
Vol 6 (10) ◽  
pp. e13712 ◽  
Author(s):  
Andrew B. Servais ◽  
Cristian D. Valenzuela ◽  
Alexandra B. Ysasi ◽  
Willi L. Wagner ◽  
Arne Kienzle ◽  
...  
Keyword(s):  
Air Leaks ◽  
Pressure Decay ◽  
Peripheral Airway ◽  
Decay Testing

scholarly journals Pressure Decay Testing Methodology for Quantifying Leak Rates of Full-Scale Docking System Seals

2009 ◽  
Author(s):  
Patrick Dunlap ◽  
Christopher Daniels ◽  
Janice Wasowski ◽  
Nicholas Garafolo ◽  
Nicholas Penney ◽  
...  
Keyword(s):  
Full Scale ◽  
Testing Methodology ◽  
Pressure Decay ◽  
Decay Testing

Monitoring membrane integrity using high sensitivity laser turbidimetry

2001 ◽  
Vol 1 (5-6) ◽  
pp. 273-276 ◽  
Author(s):  
A. Banerjee ◽  
M. Lambertson ◽  
J. Lozier ◽  
C. Colvin
Keyword(s):  
Drinking Water ◽  
Membrane Filtration ◽  
Membrane Integrity ◽  
High Sensitivity ◽  
Particle Counter ◽  
Pressure Decay ◽  
Particle Counting ◽  
Decay Test ◽  
Microfiltration Membranes ◽  
Decay Testing

Membrane filtration plants for drinking water typically use pressure decay testing in conjunction with particle counting and turbidity to monitor membrane integrity. Pilot plants offer the capability of monitoring permeate quality with both intact and intentionally compromised membranes. We compare data from a particle counter, a pressure decay test and a laser turbidimeter on pilot plants from two different manufacturers of microfiltration membranes.

Monitoring and maintaining the integrity of immersed ultrafiltration membranes used for pathogen protection

2002 ◽  
Vol 2 (5-6) ◽  
pp. 307-311
Author(s):  
P. Côté ◽  
J. Cadera ◽  
N. Adams ◽  
G. Best
Keyword(s):  
Drinking Water ◽  
Membrane Filtration ◽  
Ultrafiltration Membranes ◽  
Vacuum Decay ◽  
Integrity Monitoring ◽  
Pressure Decay ◽  
Decay Test ◽  
Conventional Technology ◽  
Water Borne

Membrane filtration has become the preferred alternative to conventional technology to remove water-borne pathogens in the preparation of drinking water. This paper presents the integrity monitoring and maintenance options for the ZeeWeed® immersed membrane. Results from two versions of air-based tests, a pressure decay test and a vacuum decay test are presented and shown to be conservative when compared to challenge results from independent studies.

scholarly journals Bio-artificial pleura using autologous dermal fibroblast sheets to mitigate air leaks during thoracoscopic lung resection

2021 ◽  
Vol 6 (1) ◽  
Author(s):  
Masato Kanzaki ◽  
Ryo Takagi ◽  
Kaoru Washio ◽  
Mami Kokubo ◽  
Shota Mitsuboshi ◽  
...  
Keyword(s):  
Dermal Fibroblast ◽  
Lung Resection ◽  
Fibroblast Cell ◽  
Patient Specific ◽  
Cell Content ◽  
Cell Monolayers ◽  
Air Leaks ◽  
Skin Biopsies ◽  
Dermal Cells ◽  
Lung Resections

AbstractLung air leaks (LALs) due to visceral pleura injury during surgery are a difficult-to-avoid complication in thoracic surgery (TS). Reliable LAL closure is an important patient management issue after TS. We demonstrated both safeties of transplantation of a cultured human autologous dermal fibroblast sheet (DFS) to LALs. From May 2016 to March 2018, five patients who underwent thoracoscopic lung resection met all the inclusion criteria. Skin biopsies were acquired from each patient to source autologous dermal cells for DFS fabrication. During the primary culture, fibroblasts migrated from the dermal tissue pieces and proliferated to form cell monolayers. These fibroblasts were subcultured to confluence. Transplantable DFSs were fabricated from these subcultured fibroblasts that were trypsinized and seeded onto temperature-responsive culture dishes. After 10 days of fabrication culture, intact patient-specific DFS were harvested. DFSs were analyzed for fibroblast cell content and tissue contaminants prior to application. For closing intraoperative LAL, mean number of transplanted autologous DFS per patient was 6 ± 2 sheets. Mean chest drainage duration was 5.0 ± 4.8 days. The two patients with major LAL had a drainage duration of more than 7 days. All patients currently have no LAL recurrence after discharge. DFSs effectively maintain LAL closure via remodeling of the deposited extracellular matrix. The use of autologous DFSs to permanently close air leaks using a patient-derived source is expected to reduce surgical complications during high-risk lung resections.

A Hyphenated Approach Combining Pressure-Decay and In Situ FT-NIR Spectroscopy to Monitor Penetrant Sorption and Concurrent Swelling in Polymers

2021 ◽  
Vol 60 (15) ◽  
pp. 5494-5503
Author(s):  
Valerio Loianno ◽  
Antonio Baldanza ◽  
Giuseppe Scherillo ◽  
Rezvan Jamaledin ◽  
Pellegrino Musto ◽  
...  
Keyword(s):  
Nir Spectroscopy ◽  
Pressure Decay

Management of Persistent Air Leaks with Intrabronchial Valves

2017 ◽  
Vol 66 (07) ◽  
pp. 603-606
Author(s):  
Andreas Hecker ◽  
Konstantin Mayer ◽  
Biruta Witte ◽  
Matthias Hecker
Keyword(s):  
Thoracic Surgery ◽  
Minimal Invasive ◽  
Therapeutic Approaches ◽  
Air Leak ◽  
Frequent Complication ◽  
Less Invasive ◽  
Air Leaks ◽  
Prolonged Hospitalization ◽  
Highly Effective ◽  
Endoscopic Placement

AbstractPersistent air leaks (PALs) are regarded as a frequent complication after thoracic surgery resulting in prolonged hospitalization and increased morbidity. Several more or less invasive therapeutic approaches are available for treatment of PAL with varying degrees of success. The endoscopic placement of one-way intrabronchial valves in the segment(s) in which the air leak has been located offers a highly effective and well-tolerated minimal invasive option for patients with PAL.

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